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TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415825(CHEMBL1091034)
Affinity DataIC50:  4nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415821(CHEMBL1093554)
Affinity DataIC50:  5nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415820(CHEMBL1093840)
Affinity DataIC50:  6.30nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19992(2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methy...)
Affinity DataIC50:  7.90nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415815(CHEMBL1092952)
Affinity DataIC50:  10nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415819(CHEMBL1091976)
Affinity DataIC50:  13nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415818(CHEMBL1093523)
Affinity DataIC50:  16nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)
Affinity DataIC50:  20nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415816(CHEMBL1093266 | GSK-2033)
Affinity DataIC50:  32nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19992(2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methy...)
Affinity DataIC50:  40nMAssay Description:Antagonist activity at LXRbeta ligand binding domain assessed as inhibition of T1317-induced transcriptional activity in african green monkey CV1 cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415817(CHEMBL1093828)
Affinity DataIC50:  79nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19992(2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methy...)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at LXRalpha ligand binding domain assessed as inhibition of T1317-induced transcriptional activity in african green monkey CV1 ce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415826(CHEMBL1090238)
Affinity DataIC50:  398nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415824(CHEMBL1090569)
Affinity DataIC50:  3.16E+3nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415822(CHEMBL1091958)
Affinity DataIC50: <1.00E+4nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415823(CHEMBL1090570)
Affinity DataIC50: <1.00E+4nMAssay Description:Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20164((1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-4-[(2S)-3,3-di...)
Affinity DataEC50:  95nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)
Affinity DataEC50:  60nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20165(3-(3-{[(3,4-dimethoxyphenyl)methyl](2,2-diphenylet...)
Affinity DataEC50:  260nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20166(2-(3-{3-[(2,2-diphenylethyl)[(4-methoxyphenyl)meth...)
Affinity DataEC50:  260nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20167(2-(3-{3-[(2,2-diphenylethyl)[(4-methoxyphenyl)meth...)
Affinity DataEC50:  860nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20168(2-[3-(3-{[(2,4-dimethoxyphenyl)methyl](2,2-dipheny...)
Affinity DataEC50:  660nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20169(2-(3-{3-[(2,2-diphenylethyl)[(3-fluoro-4-methoxyph...)
Affinity DataEC50:  250nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20170(2-(3-{3-[(2,2-diphenylethyl)[(2-fluoro-4-methoxyph...)
Affinity DataEC50:  190nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20171(2-(3-{3-[(2,2-diphenylethyl)({[3-(trifluoromethyl)...)
Affinity DataEC50:  85nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20172(2-(3-{3-[(2,2-diphenylethyl)({[4-fluoro-3-(trifluo...)
Affinity DataEC50:  85nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20173(2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...)
Affinity DataEC50:  45nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19992(2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methy...)
Affinity DataEC50:  125nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20164((1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-4-[(2S)-3,3-di...)
Affinity DataEC50:  460nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20174((1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-4-[(2R)-3,3-di...)
Affinity DataEC50:  670nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20175((1S,2R,5S,10S,11S,14S,15S)-14-[(2S)-2-hydroxy-6-me...)
Affinity DataEC50:  470nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20176((1S,2R,5S,10S,11S,14R,15S)-14-[(2S,3S)-3-hydroxy-6...)
Affinity DatapH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20177((1S,2R,5S,10S,11S,14R,15S)-14-[(2S,3R)-3-hydroxy-6...)
Affinity DataEC50:  325nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20178((1S,2R,5S,10S,11S,14R,15R)-14-[(2R,4S)-4-hydroxy-6...)
Affinity DataEC50:  5.90E+3nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20179((1S,2R,5S,10S,11S,14R,15R)-14-[(2R,4R)-4-hydroxy-6...)
Affinity DatapH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20180((1S,2R,5S,10S,11S,14R,15R)-14-[(2R,5S)-5-hydroxy-6...)
Affinity DataEC50:  130nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20181((1S,2R,5S,10S,11S,14R,15R)-14-[(2R,5R)-5-hydroxy-6...)
Affinity DataEC50:  220nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20182((1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-6-hydroxy-6-me...)
Affinity DataEC50:  1.16E+3nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20183((1S,2R,5S,10S,11S,14R,15R)-14-[(2R,6R)-7-hydroxy-6...)
Affinity DataEC50:  250nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20184((2R)-2-[(2R)-2-[(1S,2R,5S,10S,11S,14R,15R)-5-hydro...)
Affinity DatapH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20185((6R)-6-[(1S,2R,5S,10S,11S,14R,15R)-5-hydroxy-2,15-...)
Affinity DataEC50:  180nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20186((4R)-4-[(1S,2R,5S,10S,11S,14R,15R)-5-hydroxy-2,15-...)
Affinity DataEC50:  170nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20187((4R)-4-[(1S,2R,5S,10S,11S,14R,15R)-5-hydroxy-2,15-...)
Affinity DataEC50:  720nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20188(22-[N-(2 -methylpropionyl)amino]-23,24-bisnorchol-...)
Affinity DatapH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20189(1-[(2S)-2-[(1S,2R,5S,10S,11S,14R,15S)-5-hydroxy-2,...)
Affinity DatapH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20190((4R)-4-[(1S,2R,5S,10S,11S,14R,15R)-5-hydroxy-2,15-...)
Affinity DataEC50:  3.00E+3nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20191(cholenic acid methyl ester | methyl (4R)-4-[(1S,2R...)
Affinity DataEC50:  105nMpH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM20192((1S,2R,5S,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-...)
Affinity DatapH: 7.5 T: 22°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19992(2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methy...)
Affinity DataEC50:  501nMAssay Description:Agonist activity at LXRbeta ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415815(CHEMBL1092952)
Affinity DataEC50:  79nMAssay Description:Agonist activity at LXRbeta ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

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