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TargetCollagenase 3(Human)
Alantos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386430(CHEMBL2047536)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of human recombinant MMP13 using MCA-Pro-Cha-Gly-Nva-His-Ala-Dpa-NH2 as substrate preincubated for 10 mins measured by fluorescence analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Human)
Alantos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386429(CHEMBL2047537)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human recombinant MMP13 using MCA-Pro-Cha-Gly-Nva-His-Ala-Dpa-NH2 as substrate preincubated for 10 mins measured by fluorescence analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Human)
Alantos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386430(CHEMBL2047536)
Affinity DataIC50:  655nMAssay Description:Inhibition of human recombinant MMP12 using MCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 10 mins measured by fluorescence a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Human)
Alantos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386430(CHEMBL2047536)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human recombinant aggrecanase 1 using aggrecan-IGD as substrate measured after 15 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Human)
Alantos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386430(CHEMBL2047536)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of human recombinant MMP8 using MCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 10 mins measured by fluorescence an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Human)
Alantos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386429(CHEMBL2047537)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human recombinant aggrecanase 1 using aggrecan-IGD as substrate measured after 15 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Human)
Alantos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386430(CHEMBL2047536)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of human recombinant MMP3 using MCAArg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(DNP)-NH2 as substrate preincubated for 10 mins measured by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Human)
Alantos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386429(CHEMBL2047537)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human recombinant MMP3 using MCAArg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(DNP)-NH2 as substrate preincubated for 10 mins measured by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Human)
Alantos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386430(CHEMBL2047536)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant MMP1 using MCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 10 mins measured by fluorescence an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Human)
Alantos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386429(CHEMBL2047537)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant MMP2 using MCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 10 mins measured by fluorescence an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Human)
Alantos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386429(CHEMBL2047537)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant MMP8 using MCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 10 mins measured by fluorescence an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Alantos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386430(CHEMBL2047536)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant MMP9 using MCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 10 mins measured by fluorescence an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Human)
Alantos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386430(CHEMBL2047536)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant MMP7 using MCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 10 mins measured by fluorescence an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Human)
Alantos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386429(CHEMBL2047537)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant MMP7 using MCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 10 mins measured by fluorescence an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Human)
Alantos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386429(CHEMBL2047537)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant MMP12 using MCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 10 mins measured by fluorescence a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Human)
Alantos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386429(CHEMBL2047537)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant MMP14 using MCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 10 mins measured by fluorescence a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Human)
Alantos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386429(CHEMBL2047537)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant MMP1 using MCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 10 mins measured by fluorescence an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Human)
Alantos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386430(CHEMBL2047536)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant MMP2 using MCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 10 mins measured by fluorescence an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Alantos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386429(CHEMBL2047537)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant MMP9 using MCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 10 mins measured by fluorescence an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Human)
Alantos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386430(CHEMBL2047536)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant MMP14 using MCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 10 mins measured by fluorescence a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Alantos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386430(CHEMBL2047536)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant TACE using MCA-Pro-Leu-Ala-Gln-Ala-Val-Dpa-Arg-Ser-Ser-Ser-Arg-NH2 as substrate preincubated for 10 mins measured by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Alantos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386429(CHEMBL2047537)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant TACE using MCA-Pro-Leu-Ala-Gln-Ala-Val-Dpa-Arg-Ser-Ser-Ser-Arg-NH2 as substrate preincubated for 10 mins measured by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 8(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50440284(CHEMBL2424780 | US10457681, Compound Vesatolimod |...)
Affinity DataEC50:  9.00E+3nMAssay Description:Agonist activity at human TLR8 expressed in HEK293 cells by reporter based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed