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TargetDelta-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123658(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  0.180nMAssay Description:Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123658(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  0.180nMAssay Description:Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123658(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  0.460nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123658(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  0.460nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  1nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetDelta-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123655(3-[(S)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  1.06nMAssay Description:Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123647(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  1.06nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123654(CHEMBL157660 | {3-[(R)-((2S,5R)-4-Allyl-2,5-dimeth...)
Affinity DataKi:  1.18nMAssay Description:Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123664(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  1.26nMAssay Description:Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123647(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  1.37nMAssay Description:Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123649(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123649(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  1.49nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50008984(4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetMu-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123655(3-[(S)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  1.55nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123665(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  1.58nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123665(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  1.69nMAssay Description:Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123662(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  1.75nMAssay Description:Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50039026(4-((R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123664(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  1.82nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123657(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  1.88nMAssay Description:Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123660(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  1.92nMAssay Description:Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123656(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  2.01nMAssay Description:Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123652(3-[(S)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123657(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  2.16nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123650(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  2.17nMAssay Description:Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123662(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  2.19nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123648(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  2.31nMAssay Description:Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123656(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  2.35nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123660(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  2.37nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123653(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  2.41nMAssay Description:Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123654(CHEMBL157660 | {3-[(R)-((2S,5R)-4-Allyl-2,5-dimeth...)
Affinity DataKi:  2.55nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123646(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  2.73nMAssay Description:Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123648(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  2.74nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123651(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  2.75nMAssay Description:Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123653(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  2.78nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123652(3-[(S)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123650(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  3.39nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123646(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  3.46nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123659(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  6.95nMAssay Description:Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123651(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  7.06nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123659(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  7.08nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123661(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  8.88nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50123661(3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataKi:  9.20nMAssay Description:Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50039026(4-((R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl...)
Affinity DataKi:  15nMAssay Description:Binding affinity of compound evaluated for Opioid receptor mu 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  90nMAssay Description:Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50008984(4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...)
Affinity DataKi:  400nMAssay Description:Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199266(6-(4-chlorophenyl)-3-[6-(1-piperidinylmethyl)-2-na...)
Affinity DataIC50:  0.390nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50241083(6-(4-chlorophenyl)-3-(3-methoxy-4-(2-(pyrrolidin-1...)
Affinity DataIC50:  0.5nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199251(6-(4-chlorophenyl)-3-[6-(1-piperidinylmethyl)-7,8-...)
Affinity DataIC50:  0.75nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199249(6-(4-chlorophenyl)-3-[6-(1-pyrrolidinylmethyl)-7,8...)
Affinity DataIC50:  0.870nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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