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Report error Found 5 with Last Name = 'gates' and Initial = 'ks'
LigandPNGBDBM50166435(5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-...)
Affinity DataKi:  2.40E+3nM IC50:  4.80E+3nMpH: 7.0Assay Description:Assays for the reversible inhibition of PTP1B (72 nM) contained the test compound(2a, 2b, 5a, or 5b) in Bis-Tris (50 mM), NaCl (100 mM), EDTA (2 mM),...More data for this Ligand-Target Pair
LigandPNGBDBM223197(2-Bromo-N-[3'-(1,1-dioxido-4-oxo-1,2,5-thiadia...)
Affinity DataKi:  2.70E+4nM IC50:  5.40E+4nMpH: 7.0Assay Description:Assays for the reversible inhibition of PTP1B (72 nM) contained the test compound(2a, 2b, 5a, or 5b) in Bis-Tris (50 mM), NaCl (100 mM), EDTA (2 mM),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM223198(N-[3'-(1,1-Dioxido-4-oxo-1,2,5-thiadiazolidin-...)
Affinity DataKi:  3.20E+4nM IC50:  6.40E+4nMpH: 7.0Assay Description:Assays for the reversible inhibition of PTP1B (72 nM) contained the test compound(2a, 2b, 5a, or 5b) in Bis-Tris (50 mM), NaCl (100 mM), EDTA (2 mM),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM223199(5-(4-Methyl[1,1'-biphenyl]-3-yl)-1,2,5-thiadia...)
Affinity DataKi:  3.85E+4nM IC50:  7.70E+4nMpH: 7.0Assay Description:Assays for the reversible inhibition of PTP1B (72 nM) contained the test compound(2a, 2b, 5a, or 5b) in Bis-Tris (50 mM), NaCl (100 mM), EDTA (2 mM),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Missouri-Columbia

Curated by ChEMBL
LigandPNGBDBM50266095(CHEMBL444965 | ETHANEPEROXOIC ACID | peracetic aci...)
Affinity DataKi:  1.70E+7nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed