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TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161093(CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...)
Affinity DataIC50: 43nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166511(3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 95nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166504(5-Ethyl-3-[2-(2-fluoro-phenyl)-ethyl]-2-(2-hydroxy...)
Affinity DataIC50: 97nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166510(5-Ethyl-2-(2-hydroxy-phenyl)-6-methyl-3-phenethyl-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166517(5-Cyclopropyl-3-[2-(3-fluoro-phenyl)-ethyl]-2-(2-h...)
Affinity DataIC50: 120nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166503(3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 140nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166507(2-(2-Hydroxy-phenyl)-3-phenethyl-4a,5,6,7,8,8a-hex...)
Affinity DataIC50: 140nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166505(3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 160nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166512(3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 170nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166514(2-(2-Hydroxy-phenyl)-5,6-dimethyl-3-phenethyl-3H-p...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166509(3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166508(2-(2-Hydroxy-phenyl)-3-phenethyl-3,4a,5,6,7,7a-hex...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166516(2-(2-Hydroxy-phenyl)-5-methyl-3-phenethyl-6-triflu...)
Affinity DataIC50: 800nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166506(3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166515(3-[2-(2-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166513(2-(2-Hydroxy-phenyl)-6-methyl-3-phenethyl-3H-pyrim...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162542(2-Furan-2-yl-3-phenethyl-3H-quinazolin-4-one | CHE...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed