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LigandPNGBDBM50171901((R)-2-(Naphthalen-2-yloxy)-pentanoic acid | CHEMBL...)
Affinity DataEC50:  3.90E+3nMAssay Description:Effective concentration against human PPARalpha expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171897((S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid | (...)
Affinity DataEC50:  2.70E+3nMAssay Description:Effective concentration against human PPARgamma expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171904((S)-2-(4-Methoxy-phenoxy)-3-phenyl-propionic acid ...)
Affinity DataEC50:  2.01E+4nMAssay Description:Effective concentration against human PPARgamma expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171905((S)-2-(4-Acetyl-phenoxy)-3-phenyl-propionic acid |...)
Affinity DataEC50:  1.24E+4nMAssay Description:Effective concentration against human PPARgamma expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171898((S)-3-Phenyl-2-(4-trifluoromethyl-phenoxy)-propion...)
Affinity DataEC50:  500nMAssay Description:Effective concentration against human PPARalpha expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171902((S)-2-(Naphthalen-2-yloxy)-pentanoic acid | CHEMBL...)
Affinity DataEC50:  8.40E+3nMAssay Description:Effective concentration against human PPARalpha expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM28759(CHEMBL191275 | (2S)-3-phenyl-2-(4-phenylphenoxy)pr...)
Affinity DataEC50:  500nMAssay Description:Effective concentration against human PPARgamma expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171906((R)-2-(4'-Chloro-biphenyl-4-ylmethoxy)-pentanoic a...)
Affinity DataEC50:  5.40E+3nMAssay Description:Effective concentration against human PPARgamma expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171904((S)-2-(4-Methoxy-phenoxy)-3-phenyl-propionic acid ...)
Affinity DataEC50:  2.50E+3nMAssay Description:Effective concentration against human PPARalpha expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171900((S)-3-Phenyl-2-(4-thiophen-2-yl-phenoxy)-propionic...)
Affinity DataEC50:  900nMAssay Description:Effective concentration against human PPARalpha expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171897((S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid | (...)
Affinity DataEC50:  1.30nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171905((S)-2-(4-Acetyl-phenoxy)-3-phenyl-propionic acid |...)
Affinity DataEC50:  1.35E+4nMAssay Description:Effective concentration against human PPARalpha expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171898((S)-3-Phenyl-2-(4-trifluoromethyl-phenoxy)-propion...)
Affinity DataEC50:  0.270nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM24566(JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...)
Affinity DataEC50:  1.60E+3nMAssay Description:Effective concentration against human PPARalpha expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM28699(2-(4-chlorophenoxy)-2-methylpropanoic acid | CHEMB...)
Affinity DataEC50:  3.96E+4nMAssay Description:Effective concentration against human PPARalpha expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50171900((S)-3-Phenyl-2-(4-thiophen-2-yl-phenoxy)-propionic...)
Affinity DataEC50:  0.150nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171895((2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid | (...)
Affinity DataEC50:  0.350nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM24566(JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...)
Affinity DataEC50:  40nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM28681(cid_5281055 | [3H]rosiglitazone | CHEMBL121 | ROSI...)
Affinity DataEC50:  39nMAssay Description:Effective concentration against human PPARgamma expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171896((S)-2-(4-Hydroxymethyl-phenoxy)-3-phenyl-propionic...)
Affinity DataEC50:  2.87E+4nMAssay Description:Effective concentration against human PPARalpha expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171895((2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid | (...)
Affinity DataEC50:  3.60E+3nMAssay Description:Effective concentration against human PPARgamma expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171907((R)-2-(4-Chloro-phenoxy)-3-phenyl-propionic acid |...)
Affinity DataEC50:  1.05E+4nMAssay Description:Effective concentration against human PPARgamma expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171903((S)-2-(Naphthalen-2-yloxy)-3-phenyl-propionic acid...)
Affinity DataEC50:  1.50E+3nMAssay Description:Effective concentration against human PPARgamma expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171906((R)-2-(4'-Chloro-biphenyl-4-ylmethoxy)-pentanoic a...)
Affinity DataEC50:  4.00E+3nMAssay Description:Effective concentration against human PPARalpha expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171899((S)-2-(4'-Chloro-biphenyl-4-ylmethoxy)-pentanoic a...)
Affinity DataEC50:  8.90E+3nMAssay Description:Effective concentration against human PPARgamma expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM28699(2-(4-chlorophenoxy)-2-methylpropanoic acid | CHEMB...)
Affinity DataEC50:  42nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50171907((R)-2-(4-Chloro-phenoxy)-3-phenyl-propionic acid |...)
Affinity DataEC50:  1.09E+4nMAssay Description:Effective concentration against human PPARalpha expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM28763((2S)-2-(4-{2-[1,3-benzoxazol-2-yl(heptyl)amino]eth...)
Affinity DataKd:  1.98E+3nM EC50:  593nMpH: 7.5 T: 2°CAssay Description:Kd values were obtained by incubating His-PPARgamma-LBD with biotinylated peptide, europium-labeled anti-histidine antibody, and allophycocyanin-labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2009
Entry Details Article
PubMed
LigandPNGBDBM28760((2R)-3-phenyl-2-(4-phenylphenoxy)propanoic acid | ...)
Affinity DataEC50:  5.93E+3nMAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2009
Entry Details Article
PubMed
LigandPNGBDBM28681(cid_5281055 | [3H]rosiglitazone | CHEMBL121 | ROSI...)
Affinity DataEC50:  40nMAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2009
Entry Details Article
PubMed
LigandPNGBDBM28759(CHEMBL191275 | (2S)-3-phenyl-2-(4-phenylphenoxy)pr...)
Affinity DataEC50:  220nMAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2009
Entry Details Article
PubMed
LigandPNGBDBM24566(JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...)
Affinity DataEC50:  1.62E+3nMAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM28759(CHEMBL191275 | (2S)-3-phenyl-2-(4-phenylphenoxy)pr...)
Affinity DataEC50:  260nMAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2009
Entry Details Article
PubMed
LigandPNGBDBM24566(JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...)
Affinity DataEC50:  40nMAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM28760((2R)-3-phenyl-2-(4-phenylphenoxy)propanoic acid | ...)
Affinity DataAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2009
Entry Details Article
PubMed
LigandPNGBDBM28760((2R)-3-phenyl-2-(4-phenylphenoxy)propanoic acid | ...)
Affinity DataAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2009
Entry Details Article
PubMed
LigandPNGBDBM28681(cid_5281055 | [3H]rosiglitazone | CHEMBL121 | ROSI...)
Affinity DataKd:  14.8nM EC50:  3.80nMpH: 7.5 T: 2°CAssay Description:Kd values were obtained by incubating His-PPARgamma-LBD with biotinylated peptide, europium-labeled anti-histidine antibody, and allophycocyanin-labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2009
Entry Details Article
PubMed
LigandPNGBDBM28762((2R)-2-(4-{2-[1,3-benzoxazol-2-yl(heptyl)amino]eth...)
Affinity DataKd:  685nM EC50:  73.3nMpH: 7.5 T: 2°CAssay Description:Kd values were obtained by incubating His-PPARgamma-LBD with biotinylated peptide, europium-labeled anti-histidine antibody, and allophycocyanin-labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM28759(CHEMBL191275 | (2S)-3-phenyl-2-(4-phenylphenoxy)pr...)
Affinity DataEC50:  480nMAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2009
Entry Details Article
PubMed
LigandPNGBDBM50171895((2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid | (...)
Affinity DataEC50:  700nMAssay Description:Effective concentration against human PPARalpha expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM28759(CHEMBL191275 | (2S)-3-phenyl-2-(4-phenylphenoxy)pr...)
Affinity DataEC50:  0.200nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171896((S)-2-(4-Hydroxymethyl-phenoxy)-3-phenyl-propionic...)
Affinity DataEC50:  2.57E+4nMAssay Description:Effective concentration against human PPARgamma expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM28759(CHEMBL191275 | (2S)-3-phenyl-2-(4-phenylphenoxy)pr...)
Affinity DataEC50:  500nMAssay Description:Effective concentration against human PPARalpha expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171897((S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid | (...)
Affinity DataEC50:  3.90E+3nMAssay Description:Effective concentration against human PPARalpha expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171899((S)-2-(4'-Chloro-biphenyl-4-ylmethoxy)-pentanoic a...)
Affinity DataEC50:  3.90E+3nMAssay Description:Effective concentration against human PPARalpha expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171898((S)-3-Phenyl-2-(4-trifluoromethyl-phenoxy)-propion...)
Affinity DataEC50:  900nMAssay Description:Effective concentration against human PPARgamma expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171900((S)-3-Phenyl-2-(4-thiophen-2-yl-phenoxy)-propionic...)
Affinity DataEC50:  1.60E+3nMAssay Description:Effective concentration against human PPARgamma expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM28699(2-(4-chlorophenoxy)-2-methylpropanoic acid | CHEMB...)
Affinity DataEC50:  3.09E+5nMAssay Description:Effective concentration against human PPARgamma expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171901((R)-2-(Naphthalen-2-yloxy)-pentanoic acid | CHEMBL...)
Affinity DataEC50:  1.25E+4nMAssay Description:Effective concentration against human PPARgamma expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171902((S)-2-(Naphthalen-2-yloxy)-pentanoic acid | CHEMBL...)
Affinity DataEC50:  7.20E+3nMAssay Description:Effective concentration against human PPARgamma expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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