Compile Data Set for Download or QSAR
Report error Found 87 with Last Name = 'grøtli' and Initial = 'm'
TargetPyruvate kinase PKLR(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50620644(CHEMBL5427010)
Affinity DataEC50:  1.39E+3nMAssay Description:Activation of purified human PLK (unknown origin) assessed as ATP production by Kinase-Glo Max luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50604441(CHEMBL5178384)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50363397(CHEMBL1946170 | REGORAFENIB | US10183928, Regorafe...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50382959(CEP-32496 | CHEMBL2029988 | US9730937, Example 261)
Affinity DataIC50: 2nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50604450(CHEMBL5180040)
Affinity DataIC50: 3nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50322535(3-[2-(Imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-meth...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50604446(CHEMBL5200675)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50604444(CHEMBL5189744)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50604443(CHEMBL5184072)
Affinity DataIC50: 11nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50604433(CHEMBL5179230)
Affinity DataIC50: 12nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50322535(3-[2-(Imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-meth...)
Affinity DataIC50: 13nMAssay Description:Inhibition of full-length RET kinase expressed in human HEK293 cells and measured by NanoBRET assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50604445(CHEMBL5200720)
Affinity DataIC50: 15nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50604449(CHEMBL5185302)
Affinity DataIC50: 17nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50604442(CHEMBL5191715)
Affinity DataIC50: 24nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50604437(CHEMBL5182347)
Affinity DataIC50: 66nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498024(CHEMBL3326332)
Affinity DataIC50: 73nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498018(CHEMBL3326331)
Affinity DataIC50: 97nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50604435(CHEMBL5200195)
Affinity DataIC50: 98nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPyruvate kinase PKLR(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50620645(CHEMBL5429790)
Affinity DataIC50: 120nMAssay Description:Inhibition of purified human PLK (unknown origin) assessed as ATP production by Kinase-Glo Max luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPyruvate kinase PKLR(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50596765(CHEMBL5204170)
Affinity DataIC50: 150nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPyruvate kinase PKLR(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50596761(CHEMBL5209097)
Affinity DataIC50: 160nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPyruvate kinase PKLR(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50596768(CHEMBL5208105)
Affinity DataIC50: 200nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPyruvate kinase PKLR(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50596751(CHEMBL5176753)
Affinity DataIC50: 200nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPyruvate kinase PKLR(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50143419(Sodium; 3,4-dihydroxy-9,10-dioxo-9,10-dihydro-anth...)
Affinity DataIC50: 200nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50604431(CHEMBL5182833)
Affinity DataIC50: 257nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPyruvate kinase PKLR(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50596767(CHEMBL5176181)
Affinity DataIC50: 290nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPyruvate kinase PKLR(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50596760(CHEMBL5181251)
Affinity DataIC50: 300nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50604448(CHEMBL5193068)
Affinity DataIC50: 363nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPyruvate kinase PKLR(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50596766(CHEMBL5204537)
Affinity DataIC50: 550nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPyruvate kinase PKLR(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50596759(CHEMBL5188496)
Affinity DataIC50: 700nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPyruvate kinase PKLR(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50596755(CHEMBL5183208)
Affinity DataIC50: 900nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50604447(CHEMBL5203860)
Affinity DataIC50: 900nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50604442(CHEMBL5191715)
Affinity DataIC50: 920nMAssay Description:Inhibition of full-length RET kinase expressed in human HEK293 cells and measured by NanoBRET assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498026(CHEMBL3326319)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPyruvate kinase PKLR(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50596756(CHEMBL5186564)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPyruvate kinase PKLR(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50596764(CHEMBL5206382)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPyruvate kinase PKLR(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50596773(CHEMBL5195754)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPyruvate kinase PKLR(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50596771(CHEMBL5181273)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPyruvate kinase PKLR(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50596757(CHEMBL5186706)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498028(CHEMBL3326325)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50604429(CHEMBL5183486)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPyruvate kinase PKLR(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50596772(CHEMBL5200212)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50604434(CHEMBL5198379)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPyruvate kinase PKLR(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50596763(CHEMBL5198643)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50604436(CHEMBL5197023)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPyruvate kinase PKLR(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50596774(CHEMBL5177546)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498030(CHEMBL3326326)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPyruvate kinase PKLR(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50596770(CHEMBL5170574)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
Displayed 1 to 50 (of 87 total ) | Next | Last >>
Jump to: