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TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138357(US10278929, Compound 6 | US11337935, Compound 6 | ...)
Affinity DataIC50:  277nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138357(US10278929, Compound 6 | US11337935, Compound 6 | ...)
Affinity DataIC50:  277nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138357(US10278929, Compound 6 | US11337935, Compound 6 | ...)
Affinity DataIC50:  277nMAssay Description:Table 3: The FP assay was then adapted for HTS and used to screen 120,000 small molecule library for compounds that displaced probe 5 from the T4 bin...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM85507(CAS_4394-00-7 | NSC_4488 | Niflumic acid | Niflumi...)
Affinity DataIC50:  289nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM85507(CAS_4394-00-7 | NSC_4488 | Niflumic acid | Niflumi...)
Affinity DataIC50:  289nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM85507(CAS_4394-00-7 | NSC_4488 | Niflumic acid | Niflumi...)
Affinity DataIC50:  289nMAssay Description:Table 3: The FP assay was then adapted for HTS and used to screen 120,000 small molecule library for compounds that displaced probe 5 from the T4 bin...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138358(US10278929, Compound 7 | US11337935, Compound 7 | ...)
Affinity DataIC50:  296nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138358(US10278929, Compound 7 | US11337935, Compound 7 | ...)
Affinity DataIC50:  296nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138358(US10278929, Compound 7 | US11337935, Compound 7 | ...)
Affinity DataIC50:  296nMAssay Description:Table 3: The FP assay was then adapted for HTS and used to screen 120,000 small molecule library for compounds that displaced probe 5 from the T4 bin...More data for this Ligand-Target Pair
TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50308343((Z)-5-(3,5-dibromo-4-methoxybenzylidene)thiazolidi...)
Affinity DataIC50:  301nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50308343((Z)-5-(3,5-dibromo-4-methoxybenzylidene)thiazolidi...)
Affinity DataIC50:  301nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50308343((Z)-5-(3,5-dibromo-4-methoxybenzylidene)thiazolidi...)
Affinity DataIC50:  301nMAssay Description:Table 3: The FP assay was then adapted for HTS and used to screen 120,000 small molecule library for compounds that displaced probe 5 from the T4 bin...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138359(US10278929, Compound 9 | US11337935, Compound 9 | ...)
Affinity DataIC50:  329nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138359(US10278929, Compound 9 | US11337935, Compound 9 | ...)
Affinity DataIC50:  329nMAssay Description:Table 3: The FP assay was then adapted for HTS and used to screen 120,000 small molecule library for compounds that displaced probe 5 from the T4 bin...More data for this Ligand-Target Pair
TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138359(US10278929, Compound 9 | US11337935, Compound 9 | ...)
Affinity DataIC50:  329nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138360(US10278929, Compound 10 | US11337935, Compound 10 ...)
Affinity DataIC50:  433nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138360(US10278929, Compound 10 | US11337935, Compound 10 ...)
Affinity DataIC50:  433nMAssay Description:Table 3: The FP assay was then adapted for HTS and used to screen 120,000 small molecule library for compounds that displaced probe 5 from the T4 bin...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138360(US10278929, Compound 10 | US11337935, Compound 10 ...)
Affinity DataIC50:  433nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138361(US8877795, Meclofenamic Acid)
Affinity DataIC50:  504nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM383181(US10278929, Meclofenamic acid)
Affinity DataIC50:  504nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM22971(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)
Affinity DataIC50:  504nMAssay Description:Table 3: The FP assay was then adapted for HTS and used to screen 120,000 small molecule library for compounds that displaced probe 5 from the T4 bin...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM58032(2-(1,3-Dioxo-indan-2-yl)-2-(2-methyl-1H-indol-3-yl...)
Affinity DataIC50:  586nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM554486(US11337935, Compound 11)
Affinity DataIC50:  586nMAssay Description:Table 3: The FP assay was then adapted for HTS and used to screen 120,000 small molecule library for compounds that displaced probe 5 from the T4 bin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138362(US8877795, 11)
Affinity DataIC50:  586nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  653nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  653nMAssay Description:Table 3: The FP assay was then adapted for HTS and used to screen 120,000 small molecule library for compounds that displaced probe 5 from the T4 bin...More data for this Ligand-Target Pair
TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  653nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50017846(3,5-DINITROCATECHOL | 3,5-Dinitro-benzene-1,2-diol...)
Affinity DataIC50:  741nMAssay Description:Table 3: The FP assay was then adapted for HTS and used to screen 120,000 small molecule library for compounds that displaced probe 5 from the T4 bin...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM554488(US11337935, Compound 3)
Affinity DataIC50:  741nMAssay Description:Table 3: The FP assay was then adapted for HTS and used to screen 120,000 small molecule library for compounds that displaced probe 5 from the T4 bin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50017846(3,5-DINITROCATECHOL | 3,5-Dinitro-benzene-1,2-diol...)
Affinity DataIC50:  741nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50017846(3,5-DINITROCATECHOL | 3,5-Dinitro-benzene-1,2-diol...)
Affinity DataIC50:  741nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138363(US10278929, Compound Ro-41-0960 | US11337935, Comp...)
Affinity DataIC50:  755nMAssay Description:Table 3: The FP assay was then adapted for HTS and used to screen 120,000 small molecule library for compounds that displaced probe 5 from the T4 bin...More data for this Ligand-Target Pair
TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138363(US10278929, Compound Ro-41-0960 | US11337935, Comp...)
Affinity DataIC50:  755nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138363(US10278929, Compound Ro-41-0960 | US11337935, Comp...)
Affinity DataIC50:  755nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138364(US10278929, Compound 12 | US11337935, Compound 12 ...)
Affinity DataIC50:  815nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138364(US10278929, Compound 12 | US11337935, Compound 12 ...)
Affinity DataIC50:  815nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138364(US10278929, Compound 12 | US11337935, Compound 12 ...)
Affinity DataIC50:  815nMAssay Description:Table 3: The FP assay was then adapted for HTS and used to screen 120,000 small molecule library for compounds that displaced probe 5 from the T4 bin...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50334179(5-(naphthalen-1-ylmethylene)thiazolidine-2,4-dione...)
Affinity DataIC50:  842nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50334179(5-(naphthalen-1-ylmethylene)thiazolidine-2,4-dione...)
Affinity DataIC50:  842nMAssay Description:Table 3: The FP assay was then adapted for HTS and used to screen 120,000 small molecule library for compounds that displaced probe 5 from the T4 bin...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50334179(5-(naphthalen-1-ylmethylene)thiazolidine-2,4-dione...)
Affinity DataIC50:  842nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138365(US10278929, Compound 14 | US11337935, Compound 14 ...)
Affinity DataIC50:  1.15E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138365(US10278929, Compound 14 | US11337935, Compound 14 ...)
Affinity DataIC50:  1.15E+3nMAssay Description:Table 3: The FP assay was then adapted for HTS and used to screen 120,000 small molecule library for compounds that displaced probe 5 from the T4 bin...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138365(US10278929, Compound 14 | US11337935, Compound 14 ...)
Affinity DataIC50:  1.15E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138366(US10278929, Compound 15 | US11337935, Compound 15 ...)
Affinity DataIC50:  1.31E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138366(US10278929, Compound 15 | US11337935, Compound 15 ...)
Affinity DataIC50:  1.31E+3nMAssay Description:Table 3: The FP assay was then adapted for HTS and used to screen 120,000 small molecule library for compounds that displaced probe 5 from the T4 bin...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138366(US10278929, Compound 15 | US11337935, Compound 15 ...)
Affinity DataIC50:  1.31E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138367(US10278929, Compound 16 | US11337935, Compound 16 ...)
Affinity DataIC50:  2.59E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138367(US10278929, Compound 16 | US11337935, Compound 16 ...)
Affinity DataIC50:  2.59E+3nMAssay Description:Table 3: The FP assay was then adapted for HTS and used to screen 120,000 small molecule library for compounds that displaced probe 5 from the T4 bin...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138367(US10278929, Compound 16 | US11337935, Compound 16 ...)
Affinity DataIC50:  2.59E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen a ˜120,000 member small molecule library for compounds that displaced the FP probe from the ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTransthyretin(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM138368(US10278929, Compound 17 | US11337935, Compound 17 ...)
Affinity DataIC50:  2.66E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In DepthDetails US Patent

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