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Found 1875 with Last Name = 'greshock' and Initial = 'tj'
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281656(US10022461, Compound 126)
Affinity DataKi:  0.180nM ΔG°:  -55.6kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281558(US10022461, Compound 9)
Affinity DataKi:  0.220nM ΔG°:  -55.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281645(US10022461, Compound 115)
Affinity DataKi:  0.224nM ΔG°:  -55.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281561(US10022461, Compound 13)
Affinity DataKi:  0.290nM ΔG°:  -54.4kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281560(US10022461, Compound 12)
Affinity DataKi:  0.290nM ΔG°:  -54.4kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281633(US10022461, Compound 103)
Affinity DataKi:  0.320nM ΔG°:  -54.2kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281609(US10022461, Compound 59)
Affinity DataKi:  0.330nM ΔG°:  -54.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281563(US10022461, Compound 14-1)
Affinity DataKi:  0.330nM ΔG°:  -54.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281635(US10022461, Compound 105)
Affinity DataKi:  0.383nM ΔG°:  -53.7kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281559(US10022461, Compound 11-5)
Affinity DataKi:  0.400nM ΔG°:  -53.6kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281565(US10022461, Compound 16)
Affinity DataKi:  0.410nM ΔG°:  -53.6kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281639(US10022461, Compound 109)
Affinity DataKi:  0.423nM ΔG°:  -53.5kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281567(US10022461, Compound 18)
Affinity DataKi:  0.430nM ΔG°:  -53.5kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281566(US10022461, Compound 17)
Affinity DataKi:  0.430nM ΔG°:  -53.5kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281649(US10022461, Compound 119)
Affinity DataKi:  0.438nM ΔG°:  -53.4kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281623(US10022461, Compound 75)
Affinity DataKi:  0.480nM ΔG°:  -53.2kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281557(US10022461, Compound 8)
Affinity DataKi:  0.480nM ΔG°:  -53.2kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281644(US10022461, Compound 114)
Affinity DataKi:  0.494nM ΔG°:  -53.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281651(US10022461, Compound 121)
Affinity DataKi:  0.512nM ΔG°:  -53.0kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281626(US10022461, Compound 93)
Affinity DataKi:  0.530nM ΔG°:  -52.9kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281564(US10022461, Compound 15)
Affinity DataKi:  0.530nM ΔG°:  -52.9kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281555(US10022461, Compound 6)
Affinity DataKi:  0.540nM ΔG°:  -52.9kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281630(US10022461, Compound 99)
Affinity DataKi:  0.550nM ΔG°:  -52.9kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281568(US10022461, Compound 19)
Affinity DataKi:  0.620nM ΔG°:  -52.6kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281599(US10022461, Compound 49)
Affinity DataKi:  0.670nM ΔG°:  -52.4kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281642(US10022461, Compound 112)
Affinity DataKi:  0.672nM ΔG°:  -52.4kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281638(US10022461, Compound 108)
Affinity DataKi:  0.677nM ΔG°:  -52.3kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281624(US10022461, Compound 88)
Affinity DataKi:  0.690nM ΔG°:  -52.3kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281569(US10022461, Compound 20)
Affinity DataKi:  0.75nM ΔG°:  -52.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281600(US10022461, Compound 50)
Affinity DataKi:  0.75nM ΔG°:  -52.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281622(US10022461, Compound 72)
Affinity DataKi:  0.760nM ΔG°:  -52.0kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281643(US10022461, Compound 113)
Affinity DataKi:  0.784nM ΔG°:  -52.0kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281601(US10022461, Compound 51)
Affinity DataKi:  0.870nM ΔG°:  -51.7kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281628(US10022461, Compound 95)
Affinity DataKi:  0.960nM ΔG°:  -51.5kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281602(US10022461, Compound 52)
Affinity DataKi:  0.980nM ΔG°:  -51.4kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281603(US10022461, Compound 53)
Affinity DataKi:  1.02nM ΔG°:  -51.3kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281604(US10022461, Compound 54)
Affinity DataKi:  1.05nM ΔG°:  -51.2kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281631(US10022461, Compound 100)
Affinity DataKi:  1.06nM ΔG°:  -51.2kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281654(US10022461, Compound 124)
Affinity DataKi:  1.07nM ΔG°:  -51.2kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281641(US10022461, Compound 111)
Affinity DataKi:  1.09nM ΔG°:  -51.2kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281629(US10022461, Compound 98)
Affinity DataKi:  1.13nM ΔG°:  -51.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281597(US10022461, Compound 44)
Affinity DataKi:  1.13nM ΔG°:  -51.1kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281632(US10022461, Compound 101)
Affinity DataKi:  1.14nM ΔG°:  -51.0kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281605(US10022461, Compound 55)
Affinity DataKi:  1.14nM ΔG°:  -51.0kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281606(US10022461, Compound 56)
Affinity DataKi:  1.16nM ΔG°:  -51.0kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281657(US10022461, Compound 127)
Affinity DataKi:  1.17nM ΔG°:  -51.0kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281607(US10022461, Compound 57)
Affinity DataKi:  1.23nM ΔG°:  -50.9kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281646(US10022461, Compound 116)
Affinity DataKi:  1.28nM ΔG°:  -50.8kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281608(US10022461, Compound 58)
Affinity DataKi:  1.32nM ΔG°:  -50.7kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM281627(US10022461, Compound 94)
Affinity DataKi:  1.40nM ΔG°:  -50.5kJ/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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