TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 7.60nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 8.5nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 9.5nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Displacement of ovine [125I-Tyr0]-CRF from human CRF1 receptor expressed in CHO cell membrane measured after 1.5 hrs by TopCount methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Displacement of ovine [125I-Tyr0]-CRF from human CRF1 receptor expressed in CHO cell membrane measured after 1.5 hrs by TopCount methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Displacement of ovine [125I-Tyr0]-CRF from human CRF1 receptor expressed in CHO cell membrane measured after 1.5 hrs by TopCount methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Displacement of ovine [125I-Tyr0]-CRF from human CRF1 receptor expressed in CHO cell membrane measured after 1.5 hrs by TopCount methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Displacement of ovine [125I-Tyr0]-CRF from human CRF1 receptor expressed in CHO cell membrane measured after 1.5 hrs by TopCount methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Displacement of ovine [125I-Tyr0]-CRF from human CRF1 receptor expressed in CHO cell membrane measured after 1.5 hrs by TopCount methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Displacement of ovine [125I-Tyr0]-CRF from human CRF1 receptor expressed in CHO cell membrane measured after 1.5 hrs by TopCount methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Antagonist activity at human CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-stimulated adenylate cyclase activity measured after ...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Displacement of ovine [125I-Tyr0]-CRF from human CRF1 receptor expressed in CHO cell membrane measured after 1.5 hrs by TopCount methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Displacement of ovine [125I-Tyr0]-CRF from human CRF1 receptor expressed in CHO cell membrane measured after 1.5 hrs by TopCount methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Displacement of ovine [125I-Tyr0]-CRF from human CRF1 receptor expressed in CHO cell membrane measured after 1.5 hrs by TopCount methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Displacement of ovine [125I-Tyr0]-CRF from human CRF1 receptor expressed in CHO cell membrane measured after 1.5 hrs by TopCount methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:Antagonist activity at human CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-stimulated cAMP accumulation after 4 hrs by steady-gl...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Displacement of ovine [125I-Tyr0]-CRF from human CRF1 receptor expressed in CHO cell membrane measured after 1.5 hrs by TopCount methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Displacement of ovine [125I-Tyr0]-CRF from human CRF1 receptor expressed in CHO cell membrane measured after 1.5 hrs by TopCount methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Displacement of ovine [125I-Tyr0]-CRF from human CRF1 receptor expressed in CHO cell membrane measured after 1.5 hrs by TopCount methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Displacement of ovine [125I-Tyr0]-CRF from human CRF1 receptor expressed in CHO cell membrane measured after 1.5 hrs by TopCount methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Displacement of ovine [125I-Tyr0]-CRF from human CRF1 receptor expressed in CHO cell membrane measured after 1.5 hrs by TopCount methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Displacement of ovine [125I-Tyr0]-CRF from human CRF1 receptor expressed in CHO cell membrane measured after 1.5 hrs by TopCount methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 990nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
The Asan Foundation
US Patent
The Asan Foundation
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
The Asan Foundation
US Patent
The Asan Foundation
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
The Asan Foundation
US Patent
The Asan Foundation
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
The Asan Foundation
US Patent
The Asan Foundation
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
The Asan Foundation
US Patent
The Asan Foundation
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
The Asan Foundation
US Patent
The Asan Foundation
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
The Asan Foundation
US Patent
The Asan Foundation
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of ovine [125I-Tyr0]-CRF from human CRF1 receptor expressed in CHO cell membrane measured after 1.5 hrs by TopCount methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Displacement of ovine [125I-Tyr0]-CRF from human CRF1 receptor expressed in CHO cell membrane measured after 1.5 hrs by TopCount methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
