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TargetNeurotensin receptor type 1(MOUSE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50240845((S)-2-{(2S,3R)-2-[(S)-2-({(S)-1-[(S)-2-((S)-2-Amin...)
Affinity DataKi:  0.0180nMAssay Description:Binding affinity to NTR1 in mouse brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50341508((S)-N-(4-(4-Phenylbenzoylamino)butyl)-N-propyl-5-a...)
Affinity DataKi:  0.0270nMAssay Description:Displacement of [3H]7-OH-DPAT from human dopamine D3 receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50341508((S)-N-(4-(4-Phenylbenzoylamino)butyl)-N-propyl-5-a...)
Affinity DataKi:  0.0760nMAssay Description:Displacement of [3H]spiperone from wild type human dopamine D3 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50342706(3,4-Dihydro-2-[4-(4-(2-methoxyphenyl)piperazin-1-y...)
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50342704(3,4-Dihydro-2-[4-(4-(2-methoxyphenyl)piperazin-1-y...)
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50436542(CHEMBL2397389)
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50331552(CHEMBL1288585 | [11C]-(+)-(4aR,10bR)-4-propyl-3,4,...)
Affinity DataKi:  0.160nMAssay Description:Binding affinity to human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50436541(CHEMBL2396663)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50341508((S)-N-(4-(4-Phenylbenzoylamino)butyl)-N-propyl-5-a...)
Affinity DataKi:  0.190nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50188475((R)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]...)
Affinity DataKi:  0.190nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50240560(Biphenyl-4-carboxylic acid {4-[(5-hydroxy-1,2,3,4-...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50342715(3,4-Dihydro-6-(2-furyl)-2-[4-(4-(2-methoxyphenyl)p...)
Affinity DataKi:  0.210nMAssay Description:Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50274355(CHEMBL484358 | N-[N'-(4-Ethynylcyclohex-3-en-1-yl)...)
Affinity DataKi:  0.210nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50132080(Biphenyl-4-carboxylic acid {4-[4-(2-methoxy-phenyl...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50359745(CHEMBL1928128)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50342238((S)-2-((2S,3S)-2-((S)-2-((S)-1-((S)-2-((S)-3-amino...)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50119386(Benzo[b]thiophene-2-carboxylic acid {4-[4-(2-metho...)
Affinity DataKi:  0.230nMAssay Description:Binding affinity for human Dopamine receptor D3 by [3H]- spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50342239((S)-2-((2S,3S)-2-((S)-2-((S)-1-((S)-2-((S)-2-amino...)
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50436544(CHEMBL2397479)
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189854(6-bromo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl...)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50342713(3,4-Dihydro-2-[4-(4-(2-methoxyphenyl)piperazin-1-y...)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50342719(2,4-dimethyl-5-(4-methyl-5-(3-(5-(4-(trifluorometh...)
Affinity DataKi:  0.25nMAssay Description:Binding affinity to dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50342710(2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2,3...)
Affinity DataKi:  0.270nMAssay Description:Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50119386(Benzo[b]thiophene-2-carboxylic acid {4-[4-(2-metho...)
Affinity DataKi:  0.270nMAssay Description:Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50342711(7-methoxy-2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)...)
Affinity DataKi:  0.270nMAssay Description:Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50240845((S)-2-{(2S,3R)-2-[(S)-2-({(S)-1-[(S)-2-((S)-2-Amin...)
Affinity DataKi:  0.270nMAssay Description:In vitro inhibition of [3H]NT binding to porcine striatal Neurotensin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50184795(1-(2-methoxyphenyl)-4-((1-phenyl-1H-pyrazol-4-yl)m...)
Affinity DataKi:  0.280nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50203821(CHEMBL374749 | biphenyl-4-carboxylic acid {4-[4-(2...)
Affinity DataKi:  0.280nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50240845((S)-2-{(2S,3R)-2-[(S)-2-({(S)-1-[(S)-2-((S)-2-Amin...)
Affinity DataKi:  0.290nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50342705(2-[4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl]-2,3...)
Affinity DataKi:  0.290nMAssay Description:Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50359749(CHEMBL1928132)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50221673(CHEMBL394292 | N-{4-[4-(2,3-dichlorophenyl)piperaz...)
Affinity DataKi:  0.310nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50342717(4'-Acetyl-biphenyl-4-carboxylic acid {4-[4-(2-meth...)
Affinity DataKi:  0.320nMAssay Description:Binding affinity to dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50132057(CHEMBL1180430 | CHEMBL126128 | N-{4-[4-(2-Methoxy-...)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50189841(6-iodo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]...)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50132069(3-(4-Fluoro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-pip...)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50359755(CHEMBL1928137)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50294115(CHEMBL550222 | N-(4-(4-(2-(methylthio)phenyl)piper...)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50167934(CHEMBL191962 | N-{4-[4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  0.370nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D4.4 expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50203819(4-(6-fluoropyridin-2-yl)-N-{4-[4-(2-methoxyphenyl)...)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50007517((S)-3-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2-h...)
Affinity DataKi:  0.420nMAssay Description:Displacement of [3H]spiperone from dopamine D3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50436543(CHEMBL2397480)
Affinity DataKi:  0.430nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50184793(1-(2-methoxyphenyl)-4-((1-(pyridin-2-yl)-1H-pyrazo...)
Affinity DataKi:  0.440nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50132047(3-(4-Chloro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-pip...)
Affinity DataKi:  0.440nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50359747(CHEMBL1928130)
Affinity DataKi:  0.440nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50203820(4-(6-fluoropyridin-3-yl)-N-{4-[4-(2-methoxyphenyl)...)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50188476(CHEMBL209876 | N-4-[4-(3-chloro-2-methoxyphenyl)pi...)
Affinity DataKi:  0.460nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50220542(CHEMBL241169 | N-(((S)-1-allylpyrrolidin-2-yl)meth...)
Affinity DataKi:  0.460nMAssay Description:Displacement of [3H]spiperone from dopamine D3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50188475((R)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]...)
Affinity DataKi:  0.490nMAssay Description:Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50119390(Benzo[b]thiophene-2-carboxylic acid {4-[4-(2,3-dic...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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