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TargetEstrogen receptor beta(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataIC50: 2.90nMAssay Description:Displacement of fluorescent estrogen ES2 from human recombinant ERbeta by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataIC50: 3.20nMAssay Description:Displacement of fluorescent estrogen ES2 from human recombinant ERalpha by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50250229(2-(2,4-dihydroxyphenyl)-3-formyl-4-hydroxy-6-metho...)
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]estradiol from estrogen receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50250228(2-(2,4-dihydroxyphenyl)-5-hydroxy-6-methoxy-benzof...)
Affinity DataIC50: 46nMAssay Description:Displacement of [3H]estradiol from estrogen receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli MV1190 using arachidonic acid as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267227(CHEMBL4087914)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human A549 cell microsomal membrane-derived mPGES-1 assessed as reduction in conversion of PGH2 to PGE2 preincubated for 15 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50357364(CHEMBL1242095)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli MV1190 using arachidonic acid as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant 5-lipoxygenase using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267233(CHEMBL4075212)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human A549 cell microsomal membrane-derived mPGES-1 assessed as reduction in conversion of PGH2 to PGE2 preincubated for 15 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267248(CHEMBL488313 | CHEBI:2440)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human A549 cell microsomal membrane-derived mPGES-1 assessed as reduction in conversion of PGH2 to PGE2 preincubated for 15 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267243(CHEMBL1984096)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human A549 cell microsomal membrane-derived mPGES-1 assessed as reduction in conversion of PGH2 to PGE2 preincubated for 15 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267246(CHEMBL4069303)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human A549 cell microsomal membrane-derived mPGES-1 assessed as reduction in conversion of PGH2 to PGE2 preincubated for 15 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267234(Acrofolione A)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human A549 cell microsomal membrane-derived mPGES-1 assessed as reduction in conversion of PGH2 to PGE2 preincubated for 15 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50357364(CHEMBL1242095)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267227(CHEMBL4087914)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli MV1190 using arachidonic acid as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267244(CHEMBL4077368)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human A549 cell microsomal membrane-derived mPGES-1 assessed as reduction in conversion of PGH2 to PGE2 preincubated for 15 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267244(CHEMBL4077368)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli MV1190 using arachidonic acid as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50448447(CHEMBL3125444)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant 5-lipoxygenase using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267248(CHEMBL488313 | CHEBI:2440)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267246(CHEMBL4069303)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli MV1190 using arachidonic acid as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267233(CHEMBL4075212)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli MV1190 using arachidonic acid as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50006805(CHEMBL29097 | 3-(3-(tert-butylthio)-1-(4-chloroben...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human A549 cell microsomal membrane-derived mPGES-1 assessed as reduction in conversion of PGH2 to PGE2 preincubated for 15 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267245(CHEMBL4078358)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human A549 cell microsomal membrane-derived mPGES-1 assessed as reduction in conversion of PGH2 to PGE2 preincubated for 15 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267248(CHEMBL488313 | CHEBI:2440)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli MV1190 using arachidonic acid as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50357364(CHEMBL1242095)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human A549 cell microsomal membrane-derived mPGES-1 assessed as reduction in conversion of PGH2 to PGE2 preincubated for 15 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267241(CHEMBL4080027)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli MV1190 using arachidonic acid as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267247(CHEMBL4101532)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human A549 cell microsomal membrane-derived mPGES-1 assessed as reduction in conversion of PGH2 to PGE2 preincubated for 15 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267243(CHEMBL1984096)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267242(CHEMBL4096534)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267244(CHEMBL4077368)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267234(Acrofolione A)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli MV1190 using arachidonic acid as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267245(CHEMBL4078358)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267241(CHEMBL4080027)
Affinity DataIC50: 5.34E+3nMAssay Description:Inhibition of human A549 cell microsomal membrane-derived mPGES-1 assessed as reduction in conversion of PGH2 to PGE2 preincubated for 15 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267247(CHEMBL4101532)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli MV1190 using arachidonic acid as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267227(CHEMBL4087914)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267233(CHEMBL4075212)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267234(Acrofolione A)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267245(CHEMBL4078358)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli MV1190 using arachidonic acid as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267240(CHEMBL4104264)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human A549 cell microsomal membrane-derived mPGES-1 assessed as reduction in conversion of PGH2 to PGE2 preincubated for 15 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267232(CHEMBL1241050)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human A549 cell microsomal membrane-derived mPGES-1 assessed as reduction in conversion of PGH2 to PGE2 preincubated for 15 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267240(CHEMBL4104264)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli MV1190 using arachidonic acid as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267241(CHEMBL4080027)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267242(CHEMBL4096534)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli MV1190 using arachidonic acid as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267240(CHEMBL4104264)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267243(CHEMBL1984096)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli MV1190 using arachidonic acid as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267246(CHEMBL4069303)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267242(CHEMBL4096534)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human A549 cell microsomal membrane-derived mPGES-1 assessed as reduction in conversion of PGH2 to PGE2 preincubated for 15 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267247(CHEMBL4101532)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50448446(Hydroxytyrosol)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human recombinant 5-lipoxygenase using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed