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Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM93624(5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329746(CHEMBL1271731 | endo-2-((3S,5S)-3,5-dimethylmorpho...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329748(CHEMBL1271791 | endo-2-((3S,5S)-3-ethyl-5-methylmo...)
Affinity DataKi:  1nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329745(CHEMBL1271730 | endo-2-((S)-3-tert-butylmorpholino...)
Affinity DataKi:  2nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329724(CHEMBL1271960 | endo-2-((2S,6S)-2,6-dimethylpipera...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM85330(CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329744(CHEMBL1271678 | endo-2-((S)-3-isobutylmorpholino)-...)
Affinity DataKi:  3.5nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329742(CHEMBL1271629 | endo-N-((1R,5R)-9-methyl-9-azabicy...)
Affinity DataKi:  3.90nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24198(3-aminopropylphosphinic derivative, (R)-8 | [(2R)-...)
Affinity DataKi:  4.30nM ΔG°:  -47.3kJ/mole EC50:  14nMpH: 7.4 T: 22°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329741(CHEMBL1271628 | endo-2-((S)-3-ethylmorpholino)-N-(...)
Affinity DataKi:  4.60nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329730((S)-2-amino-6-chloro-N-(quinuclidin-3-yl)benzo[d]o...)
Affinity DataKi:  4.70nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329743(CHEMBL1271677 | endo-2-((S)-3-isopropylmorpholino)...)
Affinity DataKi:  5nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24195(3-aminopropylphosphinic derivative, (R)-7 | AZD335...)
Affinity DataKi:  5.10nM ΔG°:  -46.9kJ/mole EC50:  8.64nMpH: 7.4 T: 22°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329747(2-((3S,5S)-3,5-dimethylmorpholino)-N-((S)-quinucli...)
Affinity DataKi:  6.80nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329728(CHEMBL1272073 | endo-2-cyclopropyl-N-((1R,5R)-9-me...)
Affinity DataKi:  8.30nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24193((3-amino-2-fluoropropyl)phosphinic acid | 3-aminop...)
Affinity DataKi:  10nM ΔG°:  -45.2kJ/mole EC50:  15nMpH: 7.4 T: 22°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329754((S)-2-(diethylamino)-N-(quinuclidin-3-yl)benzo[d]o...)
Affinity DataKi:  12.4nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329739(CHEMBL1271570 | endo-N-(8-methyl-8-azabicyclo[3.2....)
Affinity DataKi:  12.9nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329729((S)-2-amino-N-(quinuclidin-3-yl)benzo[d]oxazole-4-...)
Affinity DataKi:  13.8nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24196((3-amino-2-fluoropropyl)(methyl)phosphinic acid | ...)
Affinity DataKi:  14nM ΔG°:  -44.4kJ/mole EC50:  23nMpH: 7.4 T: 22°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329726(CHEMBL1272017 | endo-2-(2-methoxyphenyl)-N-((1R,5R...)
Affinity DataKi:  14.9nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24184((3-aminopropyl)phosphinic acid | 3-aminopropylphos...)
Affinity DataKi:  15nM ΔG°:  -44.2kJ/mole EC50:  19nMpH: 7.4 T: 22°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329731(CHEMBL1272174 | endo-N-((1R,5R)-9-methyl-9-azabicy...)
Affinity DataKi:  15.1nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329732(CHEMBL1272175 | endo-2-(4-fluorophenyl)-N-((1R,5R)...)
Affinity DataKi:  16.3nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329751(CHEMBL1271904 | endo-N-((1R,5R)-9-methyl-9-azabicy...)
Affinity DataKi:  16.5nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329733(CHEMBL1272230 | endo-2-(4-chlorophenyl)-N-((1R,5R)...)
Affinity DataKi:  18nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329756((S)-2-(dimethylamino)-N-(quinuclidin-3-yl)benzo[d]...)
Affinity DataKi:  18.2nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329734(CHEMBL1272231 | endo-2-(4-methoxyphenyl)-N-((1R,5R...)
Affinity DataKi:  18.8nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329727((S)-2-cyclopropyl-N-(quinuclidin-3-yl)benzo[d]oxaz...)
Affinity DataKi:  32.7nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24185((3-aminopropyl)(methyl)phosphinic acid | 3-Apmpa |...)
Affinity DataKi:  33nM ΔG°:  -42.3kJ/mole EC50:  41nMpH: 7.4 T: 22°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329749(CHEMBL1271848 | endo-2-((2R,6S)-2,6-dimethylmorpho...)
Affinity DataKi:  35.3nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329758((S)-2-(methylamino)-N-(quinuclidin-3-yl)benzo[d]ox...)
Affinity DataKi:  36.4nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329757((S)-2-(ethylamino)-N-(quinuclidin-3-yl)benzo[d]oxa...)
Affinity DataKi:  36.4nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329752(CHEMBL1271905 | endo-2-((2S,6R)-2,6-dimethylpipera...)
Affinity DataKi:  37.3nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329722(CHEMBL1271519 | endo-N-((1R,5R)-9-methyl-9-azabicy...)
Affinity DataKi:  40nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329735(CHEMBL1272283 | endo-N-((1R,5R)-9-methyl-9-azabicy...)
Affinity DataKi:  40.4nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329725((S)-2-(2-methoxyphenyl)-N-(quinuclidin-8-yl)benzo[...)
Affinity DataKi:  47.3nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24191((3-amino-2-oxopropyl)phosphinic acid | (3-amino-2-...)
Affinity DataKi:  48nM ΔG°:  -41.4kJ/mole EC50:  81nMpH: 7.4 T: 22°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM24186((3-amino-2-hydroxypropyl)phosphinic acid | 3-amino...)
Affinity DataKi:  50nM ΔG°:  -41.3kJ/mole EC50:  130nMpH: 7.4 T: 22°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329738(CHEMBL1271466 | endo-2-(4-methoxyphenyl)-N-((1R,5R...)
Affinity DataKi:  58.5nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329753(CHEMBL1271959 | endo-2-((2R,6R)-2,6-dimethylpipera...)
Affinity DataKi:  59.4nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329755(2-(1-(methylamino)ethyl)-N-((S)-quinuclidin-3-yl)b...)
Affinity DataKi:  66.5nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24194(3-aminopropylphosphinic derivative, (S)-7 | [(2S)-...)
Affinity DataKi:  70nM ΔG°:  -40.4kJ/mole EC50:  250nMpH: 7.4 T: 22°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329750(CHEMBL1271849 | endo-N-((1R,5R)-9-methyl-9-azabicy...)
Affinity DataKi:  72.2nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329737(CHEMBL1271465 | endo-2-(4-chlorophenyl)-N-((1R,5R)...)
Affinity DataKi:  73.8nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329740(CHEMBL1271571 | N-((1R,5R)-9-methyl-9-azabicyclo[3...)
Affinity DataKi:  92.6nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24186((3-amino-2-hydroxypropyl)phosphinic acid | 3-amino...)
Affinity DataKi:  94nM ΔG°:  -39.7kJ/mole EC50:  220nMpH: 7.4 T: 22°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329736(CHEMBL1272284 | endo-2-(4-fluorophenyl)-N-((1R,5R)...)
Affinity DataKi:  94.9nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50329723((S)-2-morpholino-N-(quinuclidin-3-yl)benzo[d]oxazo...)
Affinity DataKi:  165nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24189(3-aminopropylphosphinic derivative, (R)-4 | 3-amin...)
Affinity DataKi:  180nM ΔG°:  -38.1kJ/mole EC50:  150nMpH: 7.4 T: 22°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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