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TargetCannabinoid receptor 1(Mus musculus (Mouse))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256379(CHEMBL482356 | methyl 3-(4-chloronaphthalen-1-ylim...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to mouse CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256378(CHEMBL482355 | methyl 3-(4-fluoronaphthalen-1-ylim...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256315(CHEMBL469895 | methyl 3-(2-methoxyphenylimino)-2-o...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256218(CHEMBL516406 | methyl 3-(naphthalen-1-ylimino)-2-o...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256318(CHEMBL481508 | methyl 3-(3-tert-butylisoxazol-5-yl...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256379(CHEMBL482356 | methyl 3-(4-chloronaphthalen-1-ylim...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256317(CHEMBL511790 | methyl 3-(4-tert-butylthiazol-2-yli...)
Affinity DataKi:  1nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256317(CHEMBL511790 | methyl 3-(4-tert-butylthiazol-2-yli...)
Affinity DataKi:  1nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256319(CHEMBL519288 | methyl 3-(3-(3-ethylpentan-3-yl)iso...)
Affinity DataKi:  1nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256319(CHEMBL519288 | methyl 3-(3-(3-ethylpentan-3-yl)iso...)
Affinity DataKi:  1nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256318(CHEMBL481508 | methyl 3-(3-tert-butylisoxazol-5-yl...)
Affinity DataKi:  1nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256431(CHEMBL480578 | methyl 3-(5,6,7,8-tetrahydronaphtha...)
Affinity DataKi:  1nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256219(CHEMBL475772 | S-methyl 3-(naphthalen-1-ylimino)-2...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256380(CHEMBL482357 | methyl 3-(4-cyanonaphthalen-1-ylimi...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256433(CHEMBL481888 | methyl 3-(4-cyano-5,6,7,8-tetrahydr...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256381(CHEMBL519635 | methyl 3-(4-nitronaphthalen-1-ylimi...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256379(CHEMBL482356 | methyl 3-(4-chloronaphthalen-1-ylim...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256377(CHEMBL449624 | methyl 3-(5-tert-butylisoxazol-3-yl...)
Affinity DataKi:  4.70nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256430(CHEMBL481716 | methyl 3-(4-(dimethylamino)naphthal...)
Affinity DataKi:  4.90nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256378(CHEMBL482355 | methyl 3-(4-fluoronaphthalen-1-ylim...)
Affinity DataKi:  4.90nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256220(CHEMBL475610 | S-methyl 3-(naphthalen-1-ylimino)-2...)
Affinity DataKi:  5.80nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256432(CHEMBL480579 | methyl 3-(4-chloro-5,6,7,8-tetrahyd...)
Affinity DataKi:  5.80nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213886(3-[(Z)-naphthalen-1-ylimino]-2-thia-4-aza-spiro[5....)
Affinity DataKi:  6nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256430(CHEMBL481716 | methyl 3-(4-(dimethylamino)naphthal...)
Affinity DataKi:  6.60nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256316(CHEMBL469896 | methyl 3-(benzo[c][1,2,5]oxadiazol-...)
Affinity DataKi:  6.80nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213886(3-[(Z)-naphthalen-1-ylimino]-2-thia-4-aza-spiro[5....)
Affinity DataKi:  6.80nMAssay Description:Binding affinity to mouse CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50032379((1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclop...)
Affinity DataKi:  8.5nMAssay Description:Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256380(CHEMBL482357 | methyl 3-(4-cyanonaphthalen-1-ylimi...)
Affinity DataKi:  9.20nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256218(CHEMBL516406 | methyl 3-(naphthalen-1-ylimino)-2-o...)
Affinity DataKi:  9.30nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256222(CHEMBL475611 | methyl 3-(phenylimino)-2-oxa-4-azas...)
Affinity DataKi:  11nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256381(CHEMBL519635 | methyl 3-(4-nitronaphthalen-1-ylimi...)
Affinity DataKi:  14nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50054804((1S,2R)-2-(1-Amino-ethyl)-1-phenyl-cyclopropanecar...)
Affinity DataKi:  14nMAssay Description:Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256431(CHEMBL480578 | methyl 3-(5,6,7,8-tetrahydronaphtha...)
Affinity DataKi:  14nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50054804((1S,2R)-2-(1-Amino-ethyl)-1-phenyl-cyclopropanecar...)
Affinity DataKi:  14nMAssay Description:Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256377(CHEMBL449624 | methyl 3-(5-tert-butylisoxazol-3-yl...)
Affinity DataKi:  17nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50157339(4-(2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-...)
Affinity DataKi:  19nMAssay Description:Inhibitory concentration against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50054802((1S,2R)-2-(1-Amino-allyl)-1-phenyl-cyclopropanecar...)
Affinity DataKi:  23nMAssay Description:Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256220(CHEMBL475610 | S-methyl 3-(naphthalen-1-ylimino)-2...)
Affinity DataKi:  31nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50068488((S)-3-(7-Carbamimidoyl-naphthalen-2-yl)-2-{4-[(S)-...)
Affinity DataKi:  41nMAssay Description:Inhibitory concentration against human Coagulation factor XMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256219(CHEMBL475772 | S-methyl 3-(naphthalen-1-ylimino)-2...)
Affinity DataKi:  49nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256315(CHEMBL469895 | methyl 3-(2-methoxyphenylimino)-2-o...)
Affinity DataKi:  59nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256432(CHEMBL480579 | methyl 3-(4-chloro-5,6,7,8-tetrahyd...)
Affinity DataKi:  76nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256433(CHEMBL481888 | methyl 3-(4-cyano-5,6,7,8-tetrahydr...)
Affinity DataKi:  101nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256316(CHEMBL469896 | methyl 3-(benzo[c][1,2,5]oxadiazol-...)
Affinity DataKi:  152nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256221(CHEMBL515604 | S-methyl 3-(naphthalen-1-ylimino)-2...)
Affinity DataKi:  155nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50054800((1R,2S)-2-(1-Amino-ethyl)-1-phenyl-cyclopropanecar...)
Affinity DataKi:  170nMAssay Description:Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50054800((1R,2S)-2-(1-Amino-ethyl)-1-phenyl-cyclopropanecar...)
Affinity DataKi:  170nMAssay Description:Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256222(CHEMBL475611 | methyl 3-(phenylimino)-2-oxa-4-azas...)
Affinity DataKi:  515nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1/Trypsin-2(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50068488((S)-3-(7-Carbamimidoyl-naphthalen-2-yl)-2-{4-[(S)-...)
Affinity DataKi:  620nMAssay Description:Inhibitory concentration against human TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256221(CHEMBL515604 | S-methyl 3-(naphthalen-1-ylimino)-2...)
Affinity DataKi:  624nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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