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Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50449568(CHEMBL2448558)
Affinity DataKd:  3.20nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor was determined by using [3H]-ICS 205-930 as radioligand in mouse N1E 115 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50000483(CHEMBL519643 | 1-Methyl-1H-indazole-3-carboxylic a...)
Affinity DataKd:  1.40nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor was determined by using [3H]-ICS 205-930 as radioligand in mouse N1E 115 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM48320(SMR000058471 | METOCLOPRAMIDE | METOCLOPRAMIDE HYD...)
Affinity DataKd:  224nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor was determined by using [3H]-ICS 205-930 as radioligand in mouse N1E 115 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50108392((3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-I...)
Affinity DataKd:  0.813nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor was determined by using [3H]-ICS 205-930 as radioligand in mouse N1E 115 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM82561(TROPANYL 3,5-DICHLOROBENZOATE | CAS_40796-97-2 | T...)
Affinity DataKd:  6.20nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor was determined by using [3H]-ICS 205-930 as radioligand in mouse N1E 115 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50014407(2-Piperazin-1-yl-quinoline (Quipazine) | CHEMBL187...)
Affinity DataKd:  2nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor was determined by using [3H]-ICS 205-930 as radioligand in mouse N1E 115 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50227348(CHEMBL41096 | SDZ-206-830)
Affinity DataKd:  0.158nMAssay Description:Potency at neuronal 5-hydroxytryptamine 3 receptor in the rabbit heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50227350(NORTROPISETRON | SDZ-206-792)
Affinity DataKd:  0.724nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor was determined by using [3H]-ICS 205-930 as radioligand in mouse N1E 115 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM85330(NSC_68647 | CAS_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataKd:  13nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor was determined by using [3H]-ICS 205-930 as radioligand in mouse N1E 115 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421836(CHEMBL12129)
Affinity DataIC50: 0.631nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex using [3H]8-OH-DPAT as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421835(CHEMBL12124)
Affinity DataIC50: 0.794nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex using [3H]8-OH-DPAT as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
Affinity DataIC50: 2.10nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor in rat frontal cortex using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM21393(cid_1220 | CHEMBL56 | 7-(dipropylamino)-5,6,7,8-te...)
Affinity DataIC50: 3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421834(CHEMBL12311)
Affinity DataIC50: 5nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex using [3H]8-OH-DPAT as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421837(CHEMBL273490)
Affinity DataIC50: 5.60nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor in rat frontal cortex using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50154716(1-Methyl-4-((S)-8-methylsulfanyl-10,11-dihydro-dib...)
Affinity DataIC50: 6.30nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor in rat frontal cortex using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421836(CHEMBL12129)
Affinity DataIC50: 10nMAssay Description:Binding affinity against alpha-1 adrenergic receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421835(CHEMBL12124)
Affinity DataIC50: 16nMAssay Description:Binding affinity against alpha-1 adrenergic receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421835(CHEMBL12124)
Affinity DataIC50: 20nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50001859(BUSPAR | CHEMBL49 | 8-[4-(4-Pyrimidin-2-yl-piperaz...)
Affinity DataIC50: 22nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421835(CHEMBL12124)
Affinity DataIC50: 63nMAssay Description:Binding affinity against alpha-1 adrenergic receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421836(CHEMBL12129)
Affinity DataIC50: 79nMAssay Description:Binding affinity against Dopamine receptor D2 in rat brain membrane using [3H]-8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50154716(1-Methyl-4-((S)-8-methylsulfanyl-10,11-dihydro-dib...)
Affinity DataIC50: 95nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex using [3H]8-OH-DPAT as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
Affinity DataIC50: 123nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421834(CHEMBL12311)
Affinity DataIC50: 158nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421834(CHEMBL12311)
Affinity DataIC50: 158nMAssay Description:Binding affinity against Dopamine receptor D2 in rat brain membrane using [3H]-8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421835(CHEMBL12124)
Affinity DataIC50: 158nMAssay Description:Binding affinity against Dopamine receptor D2 in rat brain membrane using [3H]-8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM36108((R)-propranolol)
Affinity DataIC50: 170nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex using [3H]8-OH-DPAT as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50154716(1-Methyl-4-((S)-8-methylsulfanyl-10,11-dihydro-dib...)
Affinity DataIC50: 182nMAssay Description:Binding affinity towards 5-HT1B receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421836(CHEMBL12129)
Affinity DataIC50: 200nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421838(CHEMBL11787)
Affinity DataIC50: 316nMAssay Description:Binding affinity against Dopamine receptor D2 in rat brain membrane using [3H]-8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421839(CHEMBL11824)
Affinity DataIC50: 316nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421834(CHEMBL12311)
Affinity DataIC50: 398nMAssay Description:Binding affinity against 5-HT1B receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50421835(CHEMBL12124)
Affinity DataIC50: 398nMAssay Description:Binding affinity against alpha-2 adrenergic receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM36108((R)-propranolol)
Affinity DataIC50: 490nMAssay Description:Binding affinity against 5-HT1B receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50421836(CHEMBL12129)
Affinity DataIC50: 501nMAssay Description:Binding affinity against alpha-2 adrenergic receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50421835(CHEMBL12124)
Affinity DataIC50: 631nMAssay Description:Binding affinity against alpha-2 adrenergic receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421835(CHEMBL12124)
Affinity DataIC50: 631nMAssay Description:Binding affinity against 5-HT1B receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421835(CHEMBL12124)
Affinity DataIC50: 631nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421836(CHEMBL12129)
Affinity DataIC50: 794nMAssay Description:Binding affinity against 5-HT1B receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421838(CHEMBL11787)
Affinity DataIC50: 794nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex using [3H]8-OH-DPAT as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421834(CHEMBL12311)
Affinity DataIC50: 794nMAssay Description:Binding affinity against alpha-1 adrenergic receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421835(CHEMBL12124)
Affinity DataIC50: 794nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421837(CHEMBL273490)
Affinity DataIC50: 851nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against 5-HT1B receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421838(CHEMBL11787)
Affinity DataIC50: 1.26E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421835(CHEMBL12124)
Affinity DataIC50: 2.51E+3nMAssay Description:Binding affinity against Dopamine receptor D2 in rat brain membrane using [3H]-8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421838(CHEMBL11787)
Affinity DataIC50: 3.16E+3nMAssay Description:Binding affinity against 5-HT1B receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50421837(CHEMBL273490)
Affinity DataIC50: 3.24E+3nMAssay Description:Binding affinity against 5-HT1B receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50001859(BUSPAR | CHEMBL49 | 8-[4-(4-Pyrimidin-2-yl-piperaz...)
Affinity DataIC50: 3.39E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor in rat frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
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