Report error Found 1362 with Last Name = 'hickman' and Initial = 'd'
Affinity DataEC50: 40nMAssay Description:Inhibition of BACE2 in mouse B16-F1 cells assessed as increase in intracellular PMEL17 Mbeta accumulation measured after 4 days by Western blot analy...More data for this Ligand-Target Pair
Affinity DataKd: 1.30nMAssay Description:Binding affinity to human PIM1 (15 to 313 residues) expressed in bacterial system by KINOMEScan assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.20nMAssay Description:Binding affinity to human PIM3 (16 to 317 residues) expressed in bacterial system by KINOMEScan assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.70nMAssay Description:Binding affinity to human PIM2 (1 to 291 residues) expressed in bacterial system by KINOMEScan assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.08E+4nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 7.20E+3nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.26E+4nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.06E+4nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.09E+5nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.88E+4nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.40E+5nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.66E+5nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.66E+5nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 9.00E+5nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKd: 2.96E+5nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 6.10E+3nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.00E+6nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.42E+4nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.84E+4nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.20E+3nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 320nMAssay Description:Competitive binding affinity to human BLK in presence of immobilized ligandMore data for this Ligand-Target Pair
Affinity DataKd: 290nMAssay Description:Competitive binding affinity to human BTK in presence of immobilized ligandMore data for this Ligand-Target Pair
Affinity DataKd: 220nMAssay Description:Competitive binding affinity to human wild type EGFR in presence of immobilized ligandMore data for this Ligand-Target Pair
Affinity DataKd: 0.960nMAssay Description:Competitive binding affinity to human EGFR T790M mutant in presence of immobilized ligandMore data for this Ligand-Target Pair
Affinity DataKd: 220nMAssay Description:Competitive binding affinity to human ERBB2 in presence of immobilized ligandMore data for this Ligand-Target Pair
Affinity DataKd: 130nMAssay Description:Competitive binding affinity to human ERBB4 in presence of immobilized ligandMore data for this Ligand-Target Pair
Affinity DataKd: 430nMAssay Description:Competitive binding affinity to human GAK in presence of immobilized ligandMore data for this Ligand-Target Pair
Affinity DataKd: 140nMAssay Description:Competitive binding affinity to human ITK in presence of immobilized ligandMore data for this Ligand-Target Pair
Affinity DataKd: 2.80E+3nMAssay Description:Competitive binding affinity to human JAK1 JH2 domain pseudokinase in presence of immobilized ligandMore data for this Ligand-Target Pair
Affinity DataKd: 30nMAssay Description:Competitive binding affinity to human JAK3 in presence of immobilized ligandMore data for this Ligand-Target Pair
Affinity DataKd: 81nMAssay Description:Competitive binding affinity to human TTK in presence of immobilized ligandMore data for this Ligand-Target Pair
Affinity DataKd: 410nMAssay Description:Competitive binding affinity to human TXK in presence of immobilized ligandMore data for this Ligand-Target Pair
Affinity DataKd: 310nMAssay Description:Binding affinity to wild type EGFR (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 2.60nMAssay Description:Binding affinity to EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of human full-length Pim2 expressed in Escherichia coli assessed as phosphorylation of biotinylated BAD peptide at Ser 112 preincubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of human full-length Pim2 expressed in Escherichia coli assessed as phosphorylation of biotinylated BAD peptide at Ser 112 preincubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of human full-length Pim1 expressed in Escherichia coli assessed as phosphorylation of biotinylated BAD peptide at Ser-112 preincubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of human full-length Pim1 expressed in Escherichia coli assessed as phosphorylation of biotinylated BAD peptide at Ser-112 preincubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of human full-length Pim2 expressed in Escherichia coli assessed as phosphorylation of biotinylated BAD peptide at Ser 112 preincubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of human full-length Pim2 expressed in Escherichia coli assessed as phosphorylation of biotinylated BAD peptide at Ser 112 preincubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...More data for this Ligand-Target Pair
