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TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM35997(1,4-dioxo-1,2,3,4-tetrahydro-1,2,3-benzothiadiazin...)
Affinity DataKd:  3.89E+4nM Kon:  4.99E+4M-1s-1 Koff:  1.94s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM10888(Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...)
Affinity DataKd:  4.26E+3nM Kon:  1.43E+5M-1s-1 Koff:  0.611s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM35999(2-methylbenzene-1-sulfonamide | SPR_3)
Affinity DataKd:  2.18E+3nM Kon:  1.10E+5M-1s-1 Koff:  0.240s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM36000(3,5-dichlorobenzene-1-sulfonamide | SPR_4)
Affinity DataKd:  287nM Kon:  9.02E+5M-1s-1 Koff:  0.259s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM36001(6-aminopyridine-3-sulfonamide | SPR_5)
Affinity DataKd:  1.08E+4nM Kon:  1.88E+4M-1s-1 Koff:  0.203s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM36002(2,3-dihydro-1,4-benzodioxine-6-sulfonamide | SPR_6)
Affinity DataKd:  817nM Kon:  1.34E+5M-1s-1 Koff:  0.109s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM36003(1-methyl-1H-imidazole-4-sulfonamide | SPR_7)
Affinity DataKd:  3.53E+4nM Kon:  4.65E+3M-1s-1 Koff:  0.164s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM36004(2,4-difluorobenzene-1-sulfonamide | SPR_8)
Affinity DataKd:  394nM Kon:  2.72E+5M-1s-1 Koff:  0.107s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM36005(2,3-dihydro-1H-indole-5-sulfonamide | SPR_9)
Affinity DataKd:  3.11E+3nM Kon:  1.88E+4M-1s-1 Koff:  0.0585s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM36006(2-oxo-1-propyl-2,3-dihydro-1H-1,3-benzodiazole-5-s...)
Affinity DataKd:  197nM Kon:  4.75E+5M-1s-1 Koff:  0.0935s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM36007(3-chloro-5-fluoro-2-methylbenzene-1-sulfonamide | ...)
Affinity DataKd:  96.8nM Kon:  7.88E+5M-1s-1 Koff:  0.0763s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetCarbonic anhydrase 2(Bovine)
University of Dundee

LigandPNGBDBM36008(2-amino-1,3-benzothiazole-6-sulfonamide | SPR_12)
Affinity DataKd:  383nM Kon:  5.10E+4M-1s-1 Koff:  0.0196s-1pH: 7.4 T: 2°CAssay Description:SPR biosensor assay Biacore T100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2000
Entry Details

TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50611539(CHEMBL5275211 | US20240246937, Example 1)
Affinity DataEC50:  10nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686556(US20240246937, Example 2)
Affinity DataEC50:  9nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686557(US20240246937, Example 3)
Affinity DataEC50:  12nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686558(US20240246937, Example 4)
Affinity DataEC50:  19nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686559(US20240246937, Example 5)
Affinity DataEC50:  50nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686560(US20240246937, Example 6)
Affinity DataEC50:  43nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686561(US20240246937, Example 7)
Affinity DataEC50:  9nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686562(US20240246937, Example 8)
Affinity DataEC50:  7nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686563(US20240246937, Example 9)
Affinity DataEC50:  15nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686564(US20240246937, Example 10)
Affinity DataEC50:  21nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686565(US20240246937, Example 11)
Affinity DataEC50:  16nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686566(US20240246937, Example 80 | US20240246937, Example...)
Affinity DataEC50:  8nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686567(US20240246937, Example 13)
Affinity DataEC50:  8nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50611540(CHEMBL5277779 | US20240246937, Example 14)
Affinity DataEC50:  6nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686569(US20240246937, Example 15)
Affinity DataEC50:  44nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686570(US20240246937, Example 16)
Affinity DataEC50:  16nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686571(US20240246937, Example 17)
Affinity DataEC50:  7nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686572(US20240246937, Example 18)
Affinity DataEC50:  41nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686573(US20240246937, Example 19)
Affinity DataEC50:  7nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686574(US20240246937, Example 20)
Affinity DataEC50:  5nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686575(US20240246937, Example 21)
Affinity DataEC50:  14nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686576(US20240246937, Example 22)
Affinity DataEC50:  22nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686577(US20240246937, Example 23)
Affinity DataEC50:  21nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686578(US20240246937, Example 24)
Affinity DataEC50:  30nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686579(US20240246937, Example 25)
Affinity DataEC50:  21nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686580(US20240246937, Example 26)
Affinity DataEC50:  6nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50611541(CHEMBL5269844 | US20240246937, Example 27)
Affinity DataEC50:  5nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686582(US20240246937, Example 28)
Affinity DataEC50:  8nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686583(US20240246937, Example 29)
Affinity DataEC50:  9nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686584(US20240246937, Example 30)
Affinity DataEC50:  8nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686585(US20240246937, Example 31)
Affinity DataEC50:  6nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686586(US20240246937, Example 32)
Affinity DataEC50:  5nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686587(US20240246937, Example 33)
Affinity DataEC50:  8nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686588(US20240246937, Example 34)
Affinity DataEC50:  34nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686589(US20240246937, Example 35)
Affinity DataEC50:  3nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686590(US20240246937, Example 36)
Affinity DataEC50:  6nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM686591(US20240246937, Example 37)
Affinity DataEC50:  18nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50611542(CHEMBL5267809 | US20240246937, Example 38)
Affinity DataEC50:  23nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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