BindingDB PrimarySearch_ki

Found 73 with Last Name = 'huertas-valentin' and Initial = 'l'

Dihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
University of Washington

Curated by ChEMBL

PNG

BDBM50018011(Aubagio | CHEBI:68540 | HMR-1726 | TERIFLUNOMIDE)

IC50: 17nMAssay Description:Inhibition of C-terminal His6-tagged rat DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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3D Structure (crystal)

Dihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
University of Washington

Curated by ChEMBL

PNG

BDBM50018011(Aubagio | CHEBI:68540 | HMR-1726 | TERIFLUNOMIDE)

IC50: 110nMAssay Description:Inhibition of C-terminal His6-tagged mouse DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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3D Structure (crystal)

Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50018011(Aubagio | CHEBI:68540 | HMR-1726 | TERIFLUNOMIDE)

IC50: 300nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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3D Structure (crystal)

Dihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
University of Washington

Curated by ChEMBL

PNG

BDBM50365230(CHEMBL1956285 | US9238653, Table 5, Compound 10)

IC50: 2.10E+3nMAssay Description:Inhibition of C-terminal His6-tagged mouse DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
University of Washington

Curated by ChEMBL

PNG

BDBM50365230(CHEMBL1956285 | US9238653, Table 5, Compound 10)

IC50: 4.40E+3nMAssay Description:Inhibition of C-terminal His6-tagged rat DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Cytochrome P450 3A4/3A5(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538344(CHEMBL4633246)

IC50: 5.50E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair

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Cytochrome P450 3A4/3A5(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538344(CHEMBL4633246)

IC50: 5.50E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes using testosterone as substrate preincubated for 30 mins followed by substrate addition and measured...More data for this Ligand-Target Pair

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Cytochrome P450 3A4/3A5(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538344(CHEMBL4633246)

IC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes using testosterone as substrate measured for 10 to 30 mins in presence of NADPH regenerating system ...More data for this Ligand-Target Pair

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Cytochrome P450 3A4/3A5(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538344(CHEMBL4633246)

IC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes using testosterone as substrate preincubated for 30 mins followed by substrate addition and measured...More data for this Ligand-Target Pair

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Cytochrome P450 1A2(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538344(CHEMBL4633246)

IC50: >2.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate measured for 10 to 30 mins in presence of NADPH regenerating system by U...More data for this Ligand-Target Pair

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Cytochrome P450 3A4/3A5(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538344(CHEMBL4633246)

IC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair

PDB Reactome pathway
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Cytochrome P450 2D6(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538344(CHEMBL4633246)

IC50: >2.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate measured for 10 to 30 mins in presence of NADPH regenerating syste...More data for this Ligand-Target Pair

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Cytochrome P450 2C19(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538344(CHEMBL4633246)

IC50: >2.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using (S)-mephenytoin as substrate measured for 10 to 30 mins in presence of NADPH regenerating syste...More data for this Ligand-Target Pair

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Cytochrome P450 2C9(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538344(CHEMBL4633246)

IC50: >2.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate measured for 10 to 30 mins in presence of NADPH regenerating system by ...More data for this Ligand-Target Pair

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Cytochrome P450 3A4/3A5(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538344(CHEMBL4633246)

IC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate measured for 10 to 30 mins in presence of NADPH regenerating system by ...More data for this Ligand-Target Pair

PDB Reactome pathway
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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50379157(CHEMBL1234899 | US8703811, 57)

IC50: >3.00E+4nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH (30 to 396 residues) expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate after 20...More data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50365230(CHEMBL1956285 | US9238653, Table 5, Compound 10)

IC50: >5.00E+4nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM92606(DHOD Inhibitor, 5 | US8703811, 6)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538326(CHEMBL4642145)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538327(CHEMBL4646919)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538328(CHEMBL4649039)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538329(CHEMBL4639576)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538330(CHEMBL4646226)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538331(CHEMBL4636879)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538332(CHEMBL4633356)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538333(CHEMBL4638564)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538334(CHEMBL4646287)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538335(CHEMBL4641398)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538336(CHEMBL4639489)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538337(CHEMBL4644974)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538338(CHEMBL4643370)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538339(CHEMBL4645764)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538340(CHEMBL4634278)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538341(CHEMBL4633597)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538342(CHEMBL4633302)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538343(CHEMBL4648611)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538344(CHEMBL4633246)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538345(CHEMBL4634831)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538346(CHEMBL4643327)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538347(CHEMBL4634454)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538348(CHEMBL4641948)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538349(CHEMBL4635012)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538350(CHEMBL4639806)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538351(CHEMBL4636553)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538352(CHEMBL4636157)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538353(CHEMBL4639663)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Details Article PubMed

Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538354(CHEMBL4646801)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538355(CHEMBL4636244)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

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Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538356(CHEMBL4645475)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Details Article PubMed

Dihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL

PNG

BDBM50538357(CHEMBL4643360)

IC50: >1.00E+5nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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B.MOAD DrugBank antibodypedia GoogleScholar

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