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Target5-hydroxytryptamine receptor 1B(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50033383((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Affinity DataKd:  1.5nMAssay Description:Binding affinity against 5-hydroxytryptamine 1D receptor beta using rabbit saphenous vein assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50033383((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Affinity DataKd:  0.300nMAssay Description:Binding affinity against dopamine receptor D1 in rat striatum using [3H]SCH-23390 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50033383((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Affinity DataKd:  1.80nMAssay Description:Binding affinity against 5-hydroxytryptamine 1 receptor using rabbit jugular vein assay in the absence of endotheliumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50033383((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Affinity DataKd:  1.5nMAssay Description:Binding affinity against 5-hydroxytryptamine 1D receptor beta using rabbit saphenous vein assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50033383((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Affinity DataKd:  0.0400nMAssay Description:Binding affinity against Dopamine receptor D2 in rat striatum using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50127511(4-hydroxy-2-(methoxymethyl)-5-(6-oxo-1-prop-2-ynyl...)
Affinity DataIC50: 22.3nMAssay Description:Inhibitory activity of compound against reverse transcriptase (RT) in cell free RT.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50127517(O-[5-(1-allyl-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-m...)
Affinity DataIC50: 39nMAssay Description:Inhibitory activity of compound against reverse transcriptase (RT) in cell free RT.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50127514(4-methoxy-2-(methoxymethyl)-5-(6-oxo-1-prop-2-ynyl...)
Affinity DataIC50: 150nMAssay Description:Inhibitory activity of compound against reverse transcriptase (RT) in cell free RT.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50127512((2R,3S,5R)-4-methoxy-2-(methoxymethyl)-5-(1-propyl...)
Affinity DataIC50: 820nMAssay Description:Inhibitory activity of compound against reverse transcriptase (RT) in cell free RT.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035267([2-(4-Decyloxy-3,5-dimethoxy-benzoyloxy)-ethyl]-tr...)
Affinity DataIC50: 2.00E+3nMAssay Description:Activity against adenosine diphosphate (ADP) induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035258([4-(4-Decyloxy-3,5-dimethoxy-benzoyloxy)-butyl]-tr...)
Affinity DataIC50: 2.10E+3nMAssay Description:Activity against adenosine diphosphate (ADP) induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035259([4-(4-Hexadecyloxy-3,5-dimethoxy-benzoyloxy)-butyl...)
Affinity DataIC50: 2.90E+3nMAssay Description:Activity against adenosine diphosphate (ADP) induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50127513((2R,3S,5R)-4-methoxy-2-(methoxymethyl)-5-(6-oxo-1-...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibitory activity of compound against reverse transcriptase (RT) in cell free RT.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035262([4-(3-Chloro-4-hexyloxy-5-methoxy-benzoyloxy)-buty...)
Affinity DataIC50: 9.60E+3nMAssay Description:Activity against adenosine diphosphate (ADP) induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50127515(5-(1-allyl-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-hydr...)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibitory activity of compound against reverse transcriptase (RT) in cell free RT.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035264({2-[4-(4-Hexyloxy-3,5-dimethoxy-benzoyloxy)-phenyl...)
Affinity DataIC50: 1.18E+4nMAssay Description:Activity against adenosine diphosphate (ADP) induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035260([4-(4-Hexyloxy-3,5-dimethyl-benzoyloxy)-butyl]-tri...)
Affinity DataIC50: 1.20E+4nMAssay Description:Activity against adenosine diphosphate (ADP) induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035266(5-[4-(4-Hexyloxy-3,5-dimethoxy-phenyl)-butyl]-4-me...)
Affinity DataIC50: 1.35E+4nMAssay Description:Activity against adenosine diphosphate (ADP) induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035263([4-(3,5-Dimethoxy-4-octyloxy-benzoyloxy)-butyl]-tr...)
Affinity DataIC50: 1.38E+4nMAssay Description:Activity against adenosine diphosphate (ADP) induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035265([2-(4-Hexyloxy-3,5-dimethoxy-benzoyloxymethyl)-ben...)
Affinity DataIC50: 1.60E+4nMAssay Description:Activity against adenosine diphosphate (ADP) induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035257([4-(4-Hexyloxy-benzoyloxy)-butyl]-trimethyl-ammoni...)
Affinity DataIC50: 2.25E+4nMAssay Description:Activity against adenosine diphosphate (ADP) induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50127516(5-(1-allyl-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-meth...)
Affinity DataIC50: 5.05E+4nMAssay Description:Inhibitory activity of compound against reverse transcriptase (RT) in cell free RT.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed