Compile Data Set for Download or QSAR
Found 379 with Last Name = 'itadani' and Initial = 's'
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Setsunan University

Curated by ChEMBL
LigandPNGBDBM50104905(CHEMBL3597618)
Affinity DataIC50:  0.220nMAssay Description:Antagonist activity at human CysLT1 expressed in CHOK1 cells assessed as inhibition of LTD4-induced calcium mobilization preincubated for 30 mins pri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 2(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50066948(CHEMBL3403187)
Affinity DataIC50:  0.310nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Setsunan University

Curated by ChEMBL
LigandPNGBDBM50104904(CHEMBL3597617)
Affinity DataIC50:  0.320nMAssay Description:Antagonist activity at human CysLT1 expressed in CHOK1 cells assessed as inhibition of LTD4-induced calcium mobilization preincubated for 30 mins pri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249335(US10300060, Example 15-96 | US10765676, Example 15...)
Affinity DataIC50:  0.400nMT: 2°CAssay Description:On the day before the assay, CellSenser TrkA-NFAT-bla CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249335(US10300060, Example 15-96 | US10765676, Example 15...)
Affinity DataIC50:  0.400nMAssay Description:TrkA kinase-inhibiting activity in cell systems was measured using CHO-K1 cells expressing human TrkA and NFAT-bla (CellSenser TrkA-NFAT-bla CHO-K1 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249335(US10300060, Example 15-96 | US10765676, Example 15...)
Affinity DataIC50:  0.400nMAssay Description:On the day before the assay, CellSenser™ TrkA-NFAT-b1a CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249335(US10300060, Example 15-96 | US10765676, Example 15...)
Affinity DataIC50:  0.400nMAssay Description:On the day before the assay, CellSenser TrkA-NFAT-bla CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249335(US10300060, Example 15-96 | US10765676, Example 15...)
Affinity DataIC50:  0.400nMAssay Description:On the day before the assay, CellSenser TrkA-NFAT-bla CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Setsunan University

Curated by ChEMBL
LigandPNGBDBM50104883(CHEMBL3597616)
Affinity DataIC50:  0.470nMAssay Description:Antagonist activity at human CysLT1 expressed in CHOK1 cells assessed as inhibition of LTD4-induced calcium mobilization preincubated for 30 mins pri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 2(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50066911(CHEMBL3401689)
Affinity DataIC50:  0.490nMAssay Description:Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249337(US10300060, Example 15-104 | US10765676, Example 1...)
Affinity DataIC50:  0.5nMAssay Description:On the day before the assay, CellSenser TrkA-NFAT-bla CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249337(US10300060, Example 15-104 | US10765676, Example 1...)
Affinity DataIC50:  0.5nMAssay Description:On the day before the assay, CellSenser TrkA-NFAT-bla CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249337(US10300060, Example 15-104 | US10765676, Example 1...)
Affinity DataIC50:  0.5nMT: 2°CAssay Description:On the day before the assay, CellSenser TrkA-NFAT-bla CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249337(US10300060, Example 15-104 | US10765676, Example 1...)
Affinity DataIC50:  0.5nMAssay Description:On the day before the assay, CellSenser™ TrkA-NFAT-b1a CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249337(US10300060, Example 15-104 | US10765676, Example 1...)
Affinity DataIC50:  0.5nMAssay Description:TrkA kinase-inhibiting activity in cell systems was measured using CHO-K1 cells expressing human TrkA and NFAT-bla (CellSenser TrkA-NFAT-bla CHO-K1 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Setsunan University

Curated by ChEMBL
LigandPNGBDBM50104872(CHEMBL3597535)
Affinity DataIC50:  0.560nMAssay Description:Antagonist activity at human CysLT1 expressed in CHOK1 cells assessed as inhibition of LTD4-induced calcium mobilization preincubated for 30 mins pri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Setsunan University

Curated by ChEMBL
LigandPNGBDBM50066947(CHEMBL3403186)
Affinity DataIC50:  0.590nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Setsunan University

Curated by ChEMBL
LigandPNGBDBM50104864(CHEMBL3597527)
Affinity DataIC50:  0.620nMAssay Description:Antagonist activity at human CysLT1 expressed in CHOK1 cells assessed as inhibition of LTD4-induced calcium mobilization preincubated for 30 mins pri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 2(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50033089(CHEMBL3342959)
Affinity DataIC50:  0.620nMAssay Description:Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249345(US10300060, Example 21-65 | US10765676, Example 21...)
Affinity DataIC50:  0.700nMAssay Description:TrkA kinase-inhibiting activity in cell systems was measured using CHO-K1 cells expressing human TrkA and NFAT-bla (CellSenser TrkA-NFAT-bla CHO-K1 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249345(US10300060, Example 21-65 | US10765676, Example 21...)
Affinity DataIC50:  0.700nMAssay Description:On the day before the assay, CellSenser TrkA-NFAT-bla CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249345(US10300060, Example 21-65 | US10765676, Example 21...)
Affinity DataIC50:  0.700nMT: 2°CAssay Description:On the day before the assay, CellSenser TrkA-NFAT-bla CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249345(US10300060, Example 21-65 | US10765676, Example 21...)
Affinity DataIC50:  0.700nMAssay Description:On the day before the assay, CellSenser TrkA-NFAT-bla CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249345(US10300060, Example 21-65 | US10765676, Example 21...)
Affinity DataIC50:  0.700nMAssay Description:On the day before the assay, CellSenser™ TrkA-NFAT-b1a CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Setsunan University

Curated by ChEMBL
LigandPNGBDBM50104910(CHEMBL3597623)
Affinity DataIC50:  0.790nMAssay Description:Antagonist activity at human CysLT1 expressed in CHOK1 cells assessed as inhibition of LTD4-induced calcium mobilization preincubated for 30 mins pri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Setsunan University

Curated by ChEMBL
LigandPNGBDBM50066911(CHEMBL3401689)
Affinity DataIC50:  0.790nMAssay Description:Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249336(US10300060, Example 15-98 | US10765676, Example 15...)
Affinity DataIC50:  0.800nMAssay Description:TrkA kinase-inhibiting activity in cell systems was measured using CHO-K1 cells expressing human TrkA and NFAT-bla (CellSenser TrkA-NFAT-bla CHO-K1 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249336(US10300060, Example 15-98 | US10765676, Example 15...)
Affinity DataIC50:  0.800nMAssay Description:On the day before the assay, CellSenser™ TrkA-NFAT-b1a CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249336(US10300060, Example 15-98 | US10765676, Example 15...)
Affinity DataIC50:  0.800nMAssay Description:On the day before the assay, CellSenser TrkA-NFAT-bla CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Setsunan University

Curated by ChEMBL
LigandPNGBDBM50104869(CHEMBL3597532)
Affinity DataIC50:  0.800nMAssay Description:Antagonist activity at human CysLT1 expressed in CHOK1 cells assessed as inhibition of LTD4-induced calcium mobilization preincubated for 30 mins pri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249336(US10300060, Example 15-98 | US10765676, Example 15...)
Affinity DataIC50:  0.800nMT: 2°CAssay Description:On the day before the assay, CellSenser TrkA-NFAT-bla CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249336(US10300060, Example 15-98 | US10765676, Example 15...)
Affinity DataIC50:  0.800nMAssay Description:On the day before the assay, CellSenser TrkA-NFAT-bla CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCysteinyl leukotriene receptor 2(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50033094(CHEMBL3342964)
Affinity DataIC50:  0.870nMAssay Description:Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 2(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50104905(CHEMBL3597618)
Affinity DataIC50:  0.880nMAssay Description:Antagonist activity at human CysLT2 expressed in HEK293 cells assessed as inhibition of LTD4-induced calcium mobilization preincubated for 30 mins pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 2(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50104883(CHEMBL3597616)
Affinity DataIC50:  0.890nMAssay Description:Antagonist activity at human CysLT2 expressed in HEK293 cells assessed as inhibition of LTD4-induced calcium mobilization preincubated for 30 mins pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249334(US10300060, Example 15-87 | US10765676, Example 15...)
Affinity DataIC50:  1nMAssay Description:On the day before the assay, CellSenser™ TrkA-NFAT-b1a CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249339(US10300060, Example 21-1 | US10765676, Example 21-...)
Affinity DataIC50:  1nMAssay Description:On the day before the assay, CellSenser™ TrkA-NFAT-b1a CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249340(US10300060, Example 21-2 | US10765676, Example 21-...)
Affinity DataIC50:  1nMAssay Description:On the day before the assay, CellSenser™ TrkA-NFAT-b1a CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249341(US10300060, Example 21-9 | US10765676, Example 21-...)
Affinity DataIC50:  1nMAssay Description:On the day before the assay, CellSenser™ TrkA-NFAT-b1a CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249342(US10300060, Example 21-13 | US10765676, Example 21...)
Affinity DataIC50:  1nMAssay Description:On the day before the assay, CellSenser™ TrkA-NFAT-b1a CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249343(US10300060, Example 21-37 | US10765676, Example 21...)
Affinity DataIC50:  1nMAssay Description:On the day before the assay, CellSenser™ TrkA-NFAT-b1a CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249344(US10300060, Example 21-51 | US10765676, Example 21...)
Affinity DataIC50:  1nMAssay Description:On the day before the assay, CellSenser™ TrkA-NFAT-b1a CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249350(US10300060, Example 22-8 | US10765676, Example 22-...)
Affinity DataIC50:  1nMAssay Description:On the day before the assay, CellSenser™ TrkA-NFAT-b1a CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249356(US10300060, Example 22-9 | US10765676, Example 22-...)
Affinity DataIC50:  1nMAssay Description:On the day before the assay, CellSenser™ TrkA-NFAT-b1a CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249351(US10300060, Example 22-34 | US10765676, Example 22...)
Affinity DataIC50:  1nMAssay Description:On the day before the assay, CellSenser™ TrkA-NFAT-b1a CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249357(US10300060, Example 23-3 | US10765676, Example 23-...)
Affinity DataIC50:  1nMAssay Description:On the day before the assay, CellSenser™ TrkA-NFAT-b1a CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249353(US10300060, Example 23-10 | US10765676, Example 23...)
Affinity DataIC50:  1nMAssay Description:On the day before the assay, CellSenser™ TrkA-NFAT-b1a CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249354(US10300060, Example 23-11 | US10765676, Example 23...)
Affinity DataIC50:  1nMAssay Description:On the day before the assay, CellSenser™ TrkA-NFAT-b1a CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249355(US10300060, Example 23-12 | US10765676, Example 23...)
Affinity DataIC50:  1nMAssay Description:On the day before the assay, CellSenser™ TrkA-NFAT-b1a CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

US Patent
LigandPNGBDBM249315(US10300060, Example 7 | US10765676, Example 7 | US...)
Affinity DataIC50:  1nMAssay Description:TrkA kinase-inhibiting activity in cell systems was measured using CHO-K1 cells expressing human TrkA and NFAT-bla (CellSenser TrkA-NFAT-bla CHO-K1 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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