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TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209658([({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydrop...)
Affinity DataEC50:  1.88E+3nMAssay Description:Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209659(uridine 5'-[3-alpha-D-glucopyranosyl dihydrogen di...)
Affinity DataEC50:  350nMAssay Description:Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209661([({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydrop...)
Affinity DataEC50:  880nMAssay Description:Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209663(MRS-2670 | diphosphoric acid 1-alpha-D-glucopyrano...)
Affinity DataEC50:  350nMAssay Description:Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209665(uridine 5'-[3-(alpha-D-glucopyranuronosyl) dihydro...)
Affinity DataEC50:  370nMAssay Description:Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209664(diphosphoric acid 1-alpha-D-glucopyranosyl ester 2...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209666(URIDINE-5'-DIPHOSPHATE-MANNOSE | CHEMBL227711)
Affinity DataEC50:  910nMAssay Description:Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209667(diphosphoric acid 1-alpha-D-glucopyranosuronic aci...)
Affinity DataEC50:  420nMAssay Description:Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209669(MRS-2670 | diphosphoric acid 1-alpha-D-glucopyrano...)
Affinity DataEC50:  49nMAssay Description:Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209668(Galactose-Uridine-5'-Diphosphate | CHEMBL439009)
Affinity DataEC50:  670nMAssay Description:Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50197974(udp-N-acetyl-glucosamine)
Affinity DataEC50:  810nMAssay Description:Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50197974(udp-N-acetyl-glucosamine)
Affinity DataEC50:  810nMAssay Description:Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50264215((1'R,2'R,3'S,4'R,5'S)-4'-[2-Chloro-6-(3-Bromobenzy...)
Affinity DataEC50:  4.20nMAssay Description:Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production tre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50264213((1'R,2'R,3'S,4'R,5'S)-4'-[2-Chloro-6-(3-iodobenzyl...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production tre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 2(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209659(uridine 5'-[3-alpha-D-glucopyranosyl dihydrogen di...)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50197974(udp-N-acetyl-glucosamine)
Affinity DataEC50:  4.38E+3nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209659(uridine 5'-[3-alpha-D-glucopyranosyl dihydrogen di...)
Affinity DataEC50:  261nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209669(MRS-2670 | diphosphoric acid 1-alpha-D-glucopyrano...)
Affinity DataEC50:  49nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209663(MRS-2670 | diphosphoric acid 1-alpha-D-glucopyrano...)
Affinity DataEC50:  290nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304030(Diphosphoric Acid 1''-beta-D-[1'']Glucopyranosyl E...)
Affinity DataEC50:  588nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209666(URIDINE-5'-DIPHOSPHATE-MANNOSE | CHEMBL227711)
Affinity DataEC50:  910nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209668(Galactose-Uridine-5'-Diphosphate | CHEMBL439009)
Affinity DataEC50:  670nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304031(Diphosphoric Acid 1''-alpha-D-[1'']Fucopyranosyl E...)
Affinity DataEC50:  562nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304032(URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUORO-ALPHA-D-GL...)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304033(Diphosphoric Acid 1''-alpha-D-[1''](3''-Fluoro-3''...)
Affinity DataEC50:  361nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304034(URIDINE-5'-DIPHOSPHATE-4-DEOXY-4-FLUORO-ALPHA-D-GA...)
Affinity DataEC50:  567nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304035(Diphosphoric Acid 1''-alpha-D-[1''](6''-Fluoro-6''...)
Affinity DataEC50:  905nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209665(uridine 5'-[3-(alpha-D-glucopyranuronosyl) dihydro...)
Affinity DataEC50:  370nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304036(Diphosphoric acid 1''-alpha-D-[1''](glucuronic aci...)
Affinity DataEC50:  2.59E+3nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304037({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyr...)
Affinity DataEC50:  496nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304038(Diphosphoric Acid 1''-alpha-D-[6'']Glucopyranosyl ...)
Affinity DataEC50:  373nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304039(Diphosphoric Acid 1''-alpha-D-[6'']Mannopyranosyl ...)
Affinity DataEC50:  658nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304040(Diphosphoric Acid 1''-alpha-D-[5'']Ribofuranosyl E...)
Affinity DataEC50:  238nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304041(Diphosphoric Acid 1''-alpha-D-[5'']Arabinofuranosy...)
Affinity DataEC50:  460nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209661([({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydrop...)
Affinity DataEC50:  880nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304042(Diphosphoric Acid 1''-alpha-D-[1'']Fructofuranosyl...)
Affinity DataEC50:  323nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304043({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyr...)
Affinity DataEC50:  1.88E+3nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304044([({[(2R,3R,4S,5S,6S)-6-[(2-{[(tert-butoxy)carbonyl...)
Affinity DataEC50:  951nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50197974(udp-N-acetyl-glucosamine)
Affinity DataEC50:  4.38E+3nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 2(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50366480(ATP | ADENOSINE TRIPHOSPHATE)
Affinity DataEC50:  85nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 2(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50199176(2-thio-1-beta-D-ribofuranosyl(3H)pyrimidine-2,4-di...)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 4(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50205408(2'-trifluoroacetylamino-2'-deoxy-2-thiouridine 5'-...)
Affinity DataEC50:  8.30E+3nMAssay Description:Agonist activity at human recombinant P2Y4 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 2(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50205409(({[({[(2R,3S,4R,5R)-5-(5-amino-2,4-dioxo-1,2,3,4-t...)
Affinity DataEC50:  5.60E+3nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 4(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50205405(({[({[(2R,3S,4R,5R)-4-amino-5-(2,4-dioxo-1,2,3,4-t...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human recombinant P2Y4 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50205406(2'-amino-2'-deoxy-2-thiouridine 5'-triphosphate | ...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50205407(({[({[(2R,3S,4R,5R)-5-(5-azido-2,4-dioxo-1,2,3,4-t...)
Affinity DataEC50:  467nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 2(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50270553(INS37217 | INS-37217 | CHEMBL507282)
Affinity DataEC50:  270nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50205405(({[({[(2R,3S,4R,5R)-4-amino-5-(2,4-dioxo-1,2,3,4-t...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 2(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50205412(2'-methoxy-UTP | CHEMBL220337)
Affinity DataEC50:  1.43E+4nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 2(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50205411(2'-acetylamino-2'-deoxy-2-thiouridine 5'-triphosph...)
Affinity DataEC50:  6.50E+3nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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