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TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515226(CHEMBL4476535)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50632633(CHEMBL5406591)
Affinity DataEC50:  2.91E+4nMAssay Description:Antagonist activity at PPARdelta LBD (unknown origin) assessed as increase in fluorescein labeled SMRT-ID2 corepressor peptide requirement by TR-FRET...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetAdenosine receptor A2a(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50595579(CHEMBL5203469)
Affinity DataEC50:  109nMAssay Description:Antagonist activity at human A2AAR H278A mutant A2AAR expressed in CHO cells assessed as inhibition of CGS21680-induced cAMP accumulation preincubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50383373(GSK0660 | CHEMBL592652)
Affinity DataEC50:  3.40E+3nMAssay Description:Antagonist activity at PPARdelta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAdenosine receptor A2a(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50339076((2R,3R,4S)-2-(6-amino-2-(hex-1-ynyl)-9H-purin-9-yl...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human adenosine A2A receptor expressed in CHO cells by cyclic AMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515227(CHEMBL4465968)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50383373(GSK0660 | CHEMBL592652)
Affinity DataEC50:  4.00E+3nMAssay Description:Antagonist at PPARdelta LBD (unknown origin) assessed as increase in recruitment of coactivator peptide C33 cotreated with PPARdelta agonist GW501516...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM21221(2-Cl-IB-MECA | CHEMBL431733 | C-IBzA-MU | 2-chloro...)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at human A3 adenosine receptor expressed in CHO cells assessed as inhibition of forskolin stimulated cAMP formation incubated for 45...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50085048((S)-2-(2-benzoylphenylamino)-3-(4-(2-(methyl(pyrid...)
Affinity DataEC50:  130nMAssay Description:Competitive binding affinity to GST-tagged human PPARgamma LBD incubated for 1 to 6 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50237779(CHEMBL4079448)
Affinity DataEC50:  14nMAssay Description:Competitive binding affinity to GST-tagged human PPARdelta LBD incubated for 1 to 6 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50185932(N6-(3-iodobenzyl)-9-(3-deoxy-3-ureido-B-D-ribofura...)
Affinity DataEC50:  180nMAssay Description:Activity against human adenosine A3 receptor H272E mutant expressed in COS7 cells as measured by accumulation of inositol phosphate by PLC assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50085045(5-((4-((6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-...)
Affinity DataEC50:  1.38E+3nMAssay Description:Agonist activity at PPARgamma LBD (unknown origin) assessed as increase in recruitment of coactivator peptide fluorescein-TRAP220/DRIP by TR-FRET ass...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515220(CHEMBL4544781)
Affinity DataEC50:  260nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50237779(CHEMBL4079448)
Affinity DataEC50:  7.30E+3nMAssay Description:Antagonist activity at PPARdelta LBD (unknown origin) assessed as increase in recruitment of SMRT ID2 corepressor peptide by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50595579(CHEMBL5203469)
Affinity DataKd:  1.80nMAssay Description:Displacement of [3H] ZM241385 from human A2AAR S227A mutant expressed in CHO cells assessed as dissociation constant incubated for 60 mins by radioli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetAdenosine receptor A3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50237784(CHEMBL4088081)
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at human adenosine A3 receptor expressed in CHO cells assessed as decrease in forskolin induced cAMP formation preincubated for 10 m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50555362(CHEMBL4748172)
Affinity DataEC50:  2.64E+4nMAssay Description:Antagonist activity at PPARdelta LBD (unknown origin) assessed as increase in fluorescein labeled SMRT-ID2 corepressor peptide requirement by TR-FRET...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetAdenosine receptor A2a(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50363168(CHEMBL1945563)
Affinity DataEC50:  80.3nMAssay Description:Agonist activity at human recombinant adenosine A2A receptor expressed in CHO cells assessed as induction of cAMP production after 30 mins by immunoa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50632630(CHEMBL5427431)
Affinity DataEC50:  1.63E+4nMAssay Description:Antagonist activity at PPARdelta LBD (unknown origin) assessed as increase in fluorescein labeled SMRT-ID2 corepressor peptide requirement by TR-FRET...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetAdenosine receptor A3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50496310(CHEMBL3125713)
Affinity DataEC50:  16nMAssay Description:Partial agonist activity at recombinant human adenosine A3 receptor expressed in CHO cells assessed as stimulation of forskolin-induced intracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515218(CHEMBL4538994)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515222(CHEMBL4589829)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515221(CHEMBL4538845)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50595579(CHEMBL5203469)
Affinity DataKd:  2.70nMAssay Description:Displacement of [3H] ZM241385 from human A2AAR S277A/H278A double mutant expressed in CHO cells assessed as dissociation constant incubated for 60 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50237779(CHEMBL4079448)
Affinity DataEC50:  5.20E+3nMAssay Description:Antagonist at PPARdelta LBD (unknown origin) assessed as increase in recruitment of coactivator peptide C33 cotreated with PPARdelta agonist GW501516...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50595579(CHEMBL5203469)
Affinity DataKd:  2.90nMAssay Description:Displacement of [3H] ZM241385 from human A2AAR H278A mutant expressed in CHO cells assessed as dissociation constant incubated for 60 mins by radioli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM21221(2-Cl-IB-MECA | CHEMBL431733 | C-IBzA-MU | 2-chloro...)
Affinity DataEC50:  191nMAssay Description:Competitive binding affinity to GST-tagged human PPARdelta LBD incubated for 1 to 6 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50595579(CHEMBL5203469)
Affinity DataEC50:  94nMAssay Description:Antagonist activity at human A2AAR S227A mutant expressed in CHO cells assessed as inhibition of CGS21680-induced cAMP accumulation preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50085048((S)-2-(2-benzoylphenylamino)-3-(4-(2-(methyl(pyrid...)
Affinity DataEC50:  17nMAssay Description:Agonist activity at PPARgamma LBD (unknown origin) assessed as increase in recruitment of coactivator peptide fluorescein-TRAP220/DRIP by TR-FRET ass...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50383373(GSK0660 | CHEMBL592652)
Affinity DataEC50:  4.34E+3nMAssay Description:Antagonist activity at PPARdelta LBD (unknown origin) assessed as increase in recruitment of SMRT ID2 corepressor peptide by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50177308((2S,3S,4R,5R)-5-[2-dimethylamino-6-(3-iodo-benzyla...)
Affinity DataEC50: >1.00E+4nMAssay Description:Potency against human Adenosine A2B receptor transfected in CHO cells by the stimulation of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515225(CHEMBL4464364)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50088426(3-(6-Amino-purin-9-yl)-5-hydroxymethyl-cyclopentan...)
Affinity DataEC50:  640nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50085045(5-((4-((6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-...)
Affinity DataEC50:  2.00E+3nMAssay Description:Partial agonist activity at PPARgamma LBD (unknown origin) assessed as increase in recruitment of coactivator peptide C33 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50595579(CHEMBL5203469)
Affinity DataEC50:  8.39E+3nMAssay Description:Antagonist activity at human A2AAR S277A/H278A double mutant expressed in CHO cells assessed as inhibition of CGS21680-induced cAMP accumulation prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM21221(2-Cl-IB-MECA | CHEMBL431733 | C-IBzA-MU | 2-chloro...)
Affinity DataEC50:  2.94E+3nMAssay Description:Competitive binding affinity to GST-tagged human PPARgamma LBD incubated for 1 to 6 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50580163(CHEMBL5075606)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human A3 adenosine receptor expressed in CHO cells assessed as inhibition of forskolin stimulated cAMP formation incubated for 45...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50383373(GSK0660 | CHEMBL592652)
Affinity DataEC50:  3.62E+3nMAssay Description:Antagonist activity at PPARdelta LBD (unknown origin) assessed as increase in fluorescein labeled SMRT-ID2 corepressor peptide requirement by TR-FRET...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50594422(CHEMBL5208616)
Affinity DataEC50:  1.88E+4nMAssay Description:Antagonist activity at PPARdelta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50632641(CHEMBL5431290)
Affinity DataEC50:  6.52E+3nMAssay Description:Antagonist activity at PPARdelta LBD (unknown origin) assessed as increase in fluorescein labeled SMRT-ID2 corepressor peptide requirement by TR-FRET...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetAdenosine receptor A3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50496304(CHEMBL3125712)
Affinity DataEC50:  46nMAssay Description:Partial agonist activity at recombinant human adenosine A3 receptor expressed in CHO cells assessed as stimulation of forskolin-induced intracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50085048((S)-2-(2-benzoylphenylamino)-3-(4-(2-(methyl(pyrid...)
Affinity DataEC50:  110nMAssay Description:Partial agonist activity at PPARgamma LBD (unknown origin) assessed as increase in recruitment of coactivator peptide C33 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50180197((2S,3S,4R,5R)-5-(2-chloro-6-(3-iodobenzylamino)-9H...)
Affinity DataEC50:  1.07E+4nMAssay Description:Antagonist at PPARdelta LBD (unknown origin) assessed as increase in recruitment of coactivator peptide C33 cotreated with PPARdelta agonist GW501516...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50405727(CHEMBL2115031)
Affinity DataEC50:  2.54E+3nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50180197((2S,3S,4R,5R)-5-(2-chloro-6-(3-iodobenzylamino)-9H...)
Affinity DataEC50:  41nMAssay Description:Competitive binding affinity to GST-tagged human PPARdelta LBD incubated for 1 to 6 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM28661(GW501516 | CHEMBL38943 | 2-{2-methyl-4-[({4-methyl...)
Affinity DataEC50:  1.40nMAssay Description:Competitive binding affinity to GST-tagged human PPARdelta LBD incubated for 1 to 6 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50496308(CHEMBL3125714)
Affinity DataEC50:  20nMAssay Description:Partial agonist activity at recombinant human adenosine A3 receptor expressed in CHO cells assessed as stimulation of forskolin-induced intracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50496309(CHEMBL3125719)
Affinity DataEC50:  19nMAssay Description:Partial agonist activity at recombinant human adenosine A3 receptor expressed in CHO cells assessed as stimulation of forskolin-induced intracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM21221(2-Cl-IB-MECA | CHEMBL431733 | C-IBzA-MU | 2-chloro...)
Affinity DataEC50:  2.98E+4nMAssay Description:Antagonist at PPARdelta LBD (unknown origin) assessed as increase in recruitment of coactivator peptide C33 cotreated with PPARdelta agonist GW501516...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(ZIKV)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50515219(CHEMBL4456225)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
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