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Found 296 with Last Name = 'jiménez-díaz' and Initial = 'mb'
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50603975(CHEMBL5201780)
Affinity DataIC50:  3nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50603974(CHEMBL5201904)
Affinity DataIC50:  5nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
UCB

Curated by ChEMBL
LigandPNGBDBM50591320(CHEMBL5190700)
Affinity DataIC50:  7nMAssay Description:Inhibition of PMX in Plasmodium falciparum 3D7 HA epitopeMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
UCB

Curated by ChEMBL
LigandPNGBDBM50591317(CHEMBL5191783)
Affinity DataIC50:  7nMAssay Description:Inhibition of Plasmodium falciparum recombinant C-terminal TEV cleavable 8his-tagged PMX by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
UCB

Curated by ChEMBL
LigandPNGBDBM50591320(CHEMBL5190700)
Affinity DataIC50:  7nMAssay Description:Inhibition of Plasmodium falciparum recombinant C-terminal TEV cleavable 8his-tagged PMX by FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50086051(5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-c...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50113463(CHEMBL537586)
Affinity DataIC50:  9nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
UCB

Curated by ChEMBL
LigandPNGBDBM50591318(CHEMBL5204196)
Affinity DataIC50:  9nMAssay Description:Inhibition of Plasmodium falciparum recombinant C-terminal TEV cleavable 8his-tagged PMX by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50086062(5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-c...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50086056(5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-c...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50396033(CHEMBL2169982)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50603992(CHEMBL5179988)
Affinity DataIC50:  11nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
UCB

Curated by ChEMBL
LigandPNGBDBM50591315(CHEMBL5172999)
Affinity DataIC50:  15nMAssay Description:Inhibition of Plasmodium falciparum recombinant C-terminal TEV cleavable 8his-tagged PMX by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
UCB

Curated by ChEMBL
LigandPNGBDBM50591319(CHEMBL5204856)
Affinity DataIC50:  32nMAssay Description:Inhibition of Plasmodium falciparum recombinant C-terminal TEV cleavable 8his-tagged PMX by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50603978(CHEMBL5187817)
Affinity DataIC50:  32nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
UCB

Curated by ChEMBL
LigandPNGBDBM50591316(CHEMBL5208335)
Affinity DataIC50:  37nMAssay Description:Inhibition of Plasmodium falciparum recombinant C-terminal TEV cleavable 8his-tagged PMX by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50603989(CHEMBL5192443)
Affinity DataIC50:  45nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50396034(CHEMBL586213 | TCMDC-139046)
Affinity DataIC50:  50nMAssay Description:Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
UCB

Curated by ChEMBL
LigandPNGBDBM50591315(CHEMBL5172999)
Affinity DataIC50:  58nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin D(Homo sapiens (Human))
UCB

Curated by ChEMBL
LigandPNGBDBM50591317(CHEMBL5191783)
Affinity DataIC50:  64nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50603986(CHEMBL5187610)
Affinity DataIC50:  78nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50396038(CHEMBL2169978)
Affinity DataIC50:  120nMAssay Description:Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50603988(CHEMBL5170360)
Affinity DataIC50:  140nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPlasmepsin IX(Plasmodium falciparum (isolate 3D7))
UCB

Curated by ChEMBL
LigandPNGBDBM50591320(CHEMBL5190700)
Affinity DataIC50:  142nMAssay Description:Inhibition of PMIX in Plasmodium falciparum 3D7 HA epitopeMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPlasmepsin IX(Plasmodium falciparum (isolate 3D7))
UCB

Curated by ChEMBL
LigandPNGBDBM50591320(CHEMBL5190700)
Affinity DataIC50:  142nMAssay Description:Inhibition of Plasmodium falciparum PMIX by FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
UCB

Curated by ChEMBL
LigandPNGBDBM50591317(CHEMBL5191783)
Affinity DataIC50:  180nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50396037(CHEMBL2169979)
Affinity DataIC50:  180nMAssay Description:Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50603984(CHEMBL5195201)
Affinity DataIC50:  200nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin D(Homo sapiens (Human))
UCB

Curated by ChEMBL
LigandPNGBDBM50591318(CHEMBL5204196)
Affinity DataIC50:  215nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetCytochrome P450 2C19(Homo sapiens)
Medicines for Malaria Venture

Curated by ChEMBL
LigandPNGBDBM50567995(CHEMBL4851471)
Affinity DataIC50: <250nMAssay Description:Inhibition of CYP2C19 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Medicines for Malaria Venture

Curated by ChEMBL
LigandPNGBDBM50567995(CHEMBL4851471)
Affinity DataIC50: <250nMAssay Description:Inhibition of CYP2D6 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Medicines for Malaria Venture

Curated by ChEMBL
LigandPNGBDBM50567995(CHEMBL4851471)
Affinity DataIC50: <250nMAssay Description:Inhibition of CYP2C9 (unknown origin) by UPLC-MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasmepsin IX(Plasmodium falciparum (isolate 3D7))
UCB

Curated by ChEMBL
LigandPNGBDBM50591317(CHEMBL5191783)
Affinity DataIC50:  250nMAssay Description:Inhibition of Plasmodium falciparum PMIX by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Medicines for Malaria Venture

Curated by ChEMBL
LigandPNGBDBM50567995(CHEMBL4851471)
Affinity DataIC50: <250nMAssay Description:Inhibition of CYP1A2 (unknown origin) using phenacetin O-deethylation by UPLC-MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50396032(CHEMBL2169985)
Affinity DataIC50:  390nMAssay Description:Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50030836(CHEMBL3355639)
Affinity DataIC50:  400nMAssay Description:Inhibition of human ERG potassium channel by ionworks patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50129589(CHEMBL3628223)
Affinity DataIC50:  500nMAssay Description:Inhibition of human ERG potassium channel by ionworks patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50396030(CHEMBL2169991)
Affinity DataIC50:  600nMAssay Description:Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50603985(CHEMBL5207627)
Affinity DataIC50:  690nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50603979(CHEMBL5204715)
Affinity DataIC50:  770nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50020412(CHEMBL3289811)
Affinity DataIC50:  780nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50129559(CHEMBL3234071)
Affinity DataIC50:  900nMAssay Description:Inhibition of human ERG potassium channel by ionworks patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
UCB

Curated by ChEMBL
LigandPNGBDBM50591316(CHEMBL5208335)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50090915(CHEMBL3581787)
Affinity DataIC50:  1.17E+3nMAssay Description:Inhibition of human ERG by IonWorks electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50285940(CHEMBL4163616)
Affinity DataIC50:  1.18E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
UCB

Curated by ChEMBL
LigandPNGBDBM50591316(CHEMBL5208335)
Affinity DataIC50:  1.19E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50396031(CHEMBL2169990)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50603976(CHEMBL5200247)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50603983(CHEMBL5181699)
Affinity DataIC50:  1.33E+3nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50129562(CHEMBL3628220)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human ERG potassium channel by ionworks patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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