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TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289769(US10093673, Compound 1.1)
Affinity DataEC50:  0.100nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM246811(cis-10-methoxy-11-(3-methoxypropoxy)-3,3-dimethyl-...)
Affinity DataEC50:  13nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM246810(trans-10-methoxy-11-(3-methoxypropoxy)-3,3-dimethy...)
Affinity DataEC50:  460nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289772(US10093673, Compound 3.1)
Affinity DataEC50:  0.300nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289773(US10093673, Compound 3.2)
Affinity DataEC50:  740nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289774(US10093673, Compound 4.1)
Affinity DataEC50:  0.300nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289775(US10093673, Compound 5.1)
Affinity DataEC50:  6nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289776(US10093673, Compound 5.2)
Affinity DataEC50:  0.100nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289777(US10093673, Compound 6.1 | US10093673, Compound 6....)
Affinity DataEC50:  9nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289777(US10093673, Compound 6.1 | US10093673, Compound 6....)
Affinity DataEC50:  5nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289779(US10093673, Compound 7.1)
Affinity DataEC50:  0.800nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289780(US10093673, Compound 7.2)
Affinity DataEC50:  90nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289781(US10093673, Compound 8.1)
Affinity DataEC50:  1nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289782(US10093673, Compound 9.1 | US10093673, Compound 9....)
Affinity DataEC50:  9nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetLarge envelope protein(HBV-D)
Novartis

US Patent
LigandPNGBDBM289782(US10093673, Compound 9.1 | US10093673, Compound 9....)
Affinity DataEC50:  303nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50520522(CHEMBL4568628)
Affinity DataKd:  80nMAssay Description:Binding affinity to recombinant human IDO1 assessed as equilibrium dissociation constant by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50520522(CHEMBL4568628)
Affinity DataKd:  0.00450nMAssay Description:Binding affinity to recombinant human IDO1 assessed as kinetic dissociation constant by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50520522(CHEMBL4568628)
Affinity DataKd:  530nMAssay Description:Binding affinity to STAT3 in human SKOV3 cells assessed as equilibrium dissociation constant after 200 sec by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573584(CHEMBL4845782)
Affinity DataEC50:  104nMAssay Description:Inhibition of PD1/PDL1 protein-protein interaction in human Jurkat cells overexpressing PD1 co-cultured with human Hep3B cells expressing PDL1 protei...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573585(CHEMBL4846412)
Affinity DataEC50:  775nMAssay Description:Inhibition of PD1/PDL1 protein-protein interaction in human Jurkat cells overexpressing PD1 co-cultured with human Hep3B cells expressing PDL1 protei...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573586(CHEMBL4867169)
Affinity DataEC50:  376nMAssay Description:Inhibition of PD1/PDL1 protein-protein interaction in human Jurkat cells overexpressing PD1 co-cultured with human Hep3B cells expressing PDL1 protei...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578585(CHEMBL4859591)
Affinity DataEC50:  17nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578586(CHEMBL4870623)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578587(CHEMBL4873280)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578588(CHEMBL4846631)
Affinity DataEC50:  4.5nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578589(CHEMBL4874945)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578590(CHEMBL4872480)
Affinity DataEC50:  4.30nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578591(CHEMBL4872653)
Affinity DataEC50:  78nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578592(CHEMBL4867311)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM25392(Isoproterenol,(+) | CHEMBL434 | 4-[1-hydroxy-2-(pr...)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM25771(salmeterol xinafoate | 4-(1-hydroxy-2-{[6-(4-pheny...)
Affinity DataEC50:  372nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50569861(CHEBI:82700 | Olodaterol | BI 1744 | Striverdi res...)
Affinity DataEC50:  123nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578593(CHEMBL4860764)
Affinity DataEC50:  4.60nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578594(CHEMBL4847767)
Affinity DataEC50:  4.5nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578595(CHEMBL4853372)
Affinity DataEC50:  6.30nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578596(CHEMBL4854569)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578597(CHEMBL4863282)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578598(CHEMBL4860454)
Affinity DataEC50:  45nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578599(CHEMBL4868684)
Affinity DataEC50:  3.10nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578600(CHEMBL4868763)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578601(CHEMBL4848018)
Affinity DataEC50:  6.80nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578602(CHEMBL4865833)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578603(CHEMBL4873082)
Affinity DataEC50:  4.10nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578604(CHEMBL4847536)
Affinity DataEC50:  4.5nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578605(CHEMBL4848793)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578606(CHEMBL4865514)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578607(CHEMBL4848617)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578608(CHEMBL4848775)
Affinity DataEC50:  7.80nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578609(CHEMBL4863847)
Affinity DataEC50:  7.60nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50578610(CHEMBL4857267)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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