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TargetThymidylate synthase(Human)
Pedagogical University

Curated by ChEMBL
LigandPNGBDBM50405732(CHEMBL290277)
Affinity DataKi:  0.0410nMAssay Description:Compound was tested for inhibition of human (WI-L2) thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Pedagogical University

Curated by ChEMBL
LigandPNGBDBM50405733(CHEMBL406575)
Affinity DataKi:  0.0420nMAssay Description:Compound was tested for inhibition of human (WI-L2) thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Pedagogical University

Curated by ChEMBL
LigandPNGBDBM50405731(CHEMBL295708)
Affinity DataKi:  0.0720nMAssay Description:Compound was tested for inhibition of human (WI-L2) thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50069352((1-{(R)-1-{3-[(E)-2-(7,7-Dimethyl-5,6,7,8-tetrahyd...)
Affinity DataIC50: 0.170nMAssay Description:In vitro inhibition of [3H]LTD4 binding to LTD4 receptor of guinea pig lung membrane with human serum albumin (HSA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50069356([1-((R)-3-[2-(1-Hydroxy-1-methyl-ethyl)-phenyl]-1-...)
Affinity DataIC50: 0.190nMAssay Description:In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50069352((1-{(R)-1-{3-[(E)-2-(7,7-Dimethyl-5,6,7,8-tetrahyd...)
Affinity DataIC50: 0.190nMAssay Description:In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50280701(Sodium; (R)-3-{(R)-1-[3-(7-chloro-quinolin-2-ylmet...)
Affinity DataIC50: 0.200nMAssay Description:Inhibitory concentration against [3H]Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50286261((S)-2-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vi...)
Affinity DataIC50: 0.200nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes (different expt)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1/2(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50069375((R)-2-(1-((1-(3-(2-(5,7-dihydrothieno[3,4-b]pyridi...)
Affinity DataIC50: 0.210nMAssay Description:In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Pedagogical University

Curated by ChEMBL
LigandPNGBDBM50405730(CHEMBL295681)
Affinity DataKi:  0.224nMAssay Description:Compound was tested for inhibition of human (WI-L2) thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50069356([1-((R)-3-[2-(1-Hydroxy-1-methyl-ethyl)-phenyl]-1-...)
Affinity DataIC50: 0.25nMAssay Description:In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of DMSO differentiated human U937 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50286260(4-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]...)
Affinity DataIC50: 0.300nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes (different expt)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50280701(Sodium; (R)-3-{(R)-1-[3-(7-chloro-quinolin-2-ylmet...)
Affinity DataIC50: 0.300nMAssay Description:Inhibitory concentration against [3H]Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50001273(CHEMBL124095 | 3-((2-Carbamoyl-ethylsulfanyl)-{3-[...)
Affinity DataIC50: 0.300nMAssay Description:In vitro inhibition of [3H]LTD4 binding to guinea pig lung membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50286257((2R,3R)-3-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl...)
Affinity DataIC50: 0.300nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes (different expt)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50286253((S)-3-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vi...)
Affinity DataIC50: 0.330nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes (different expt)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1/2(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50069372((1-{(R)-1-{3-[(E)-2-(6,6-Dimethyl-6,7-dihydro-5H-[...)
Affinity DataIC50: 0.340nMAssay Description:In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50069350((1-{(R)-1-{3-[(E)-2-(7,7-Dimethyl-6,7-dihydro-5H-[...)
Affinity DataIC50: 0.350nMAssay Description:In vitro inhibition of [3H]LTD4 binding to LTD4 receptor of guinea pig lung membrane with human serum albumin (HSA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50280712(Sodium; 3-{1-[3-(7-chloro-quinolin-2-ylmethoxy)-ph...)
Affinity DataIC50: 0.360nMAssay Description:Inhibitory concentration against [3H]Leukotriene D4 binding to guinea-pig lung membranes was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50285678((1-{(R)-1-{3-[(E)-2-(2,3-Dichloro-thieno[3,2-b]pyr...)
Affinity DataIC50: 0.380nMAssay Description:Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50280713(Sodium; 2-{1-[3-(7-chloro-quinolin-2-ylmethoxy)-ph...)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory concentration against [3H]Leukotriene D4 binding to guinea-pig lung membranes was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50280693(Sodium; 3-[1-[3-(7-chloro-quinolin-2-ylmethoxy)-ph...)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory concentration against [3H]Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50069352((1-{(R)-1-{3-[(E)-2-(7,7-Dimethyl-5,6,7,8-tetrahyd...)
Affinity DataIC50: 0.420nMAssay Description:In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of DMSO differentiated human U937 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50069372((1-{(R)-1-{3-[(E)-2-(6,6-Dimethyl-6,7-dihydro-5H-[...)
Affinity DataIC50: 0.430nMAssay Description:In vitro inhibition of [3H]LTD4 binding to LTD4 receptor of guinea pig lung membrane with human serum albumin (HSA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50052024(montelukast | CHEMBL787)
Affinity DataIC50: 0.430nMAssay Description:In vitro inhibition of [3H]LTD4 binding to LTD4 receptor of guinea pig lung membrane with human serum albumin (HSA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50286262(4-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]...)
Affinity DataIC50: 0.430nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes (different expt)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50069355((R)-2-(1-((1-(3-(2-(6,7-dihydro-5H-cyclopenta[b]py...)
Affinity DataIC50: 0.440nMAssay Description:In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of DMSO differentiated human U937 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50286255(3-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]...)
Affinity DataIC50: 0.440nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes (different expt)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50009073(cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...)
Affinity DataIC50: 0.440nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes (different expt)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50280687(Sodium; 2-[1-[3-(7-chloro-quinolin-2-ylmethoxy)-ph...)
Affinity DataIC50: 0.450nMAssay Description:Inhibitory concentration against [3H]Leukotriene D4 binding to guinea-pig lung membranes was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50280686(Sodium; 2-{3-(2-carbamoyl-phenyl)-1-[3-(7-chloro-q...)
Affinity DataIC50: 0.470nMAssay Description:Inhibitory concentration against [3H]Leukotriene D4 binding to guinea-pig lung membranes was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50285677((1-{(R)-1-{3-[(E)-2-(2,3-Dichloro-thieno[3,2-b]pyr...)
Affinity DataIC50: 0.470nMAssay Description:Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50069373(2-(1-(((1R)-3-(2-(2-hydroxypropan-2-yl)phenyl)-1-(...)
Affinity DataIC50: 0.470nMAssay Description:In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of DMSO differentiated human U937 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50280693(Sodium; 3-[1-[3-(7-chloro-quinolin-2-ylmethoxy)-ph...)
Affinity DataIC50: 0.490nMAssay Description:Inhibitory concentration against [3H]Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50128685(2-{5-[1-(3-Cyclobutoxy-4-difluoromethoxy-phenyl)-2...)
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibitory activity was determined against human Phosphodiesterase 4 isoform using a construct representing the common region of spliced var...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50069355((R)-2-(1-((1-(3-(2-(6,7-dihydro-5H-cyclopenta[b]py...)
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50052024(montelukast | CHEMBL787)
Affinity DataIC50: 0.5nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes (different expt)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50113417(4-{2-(3,4-Bis-difluoromethoxy-phenyl)-2-[4-(4-fluo...)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory concentration against human PDE4A isoform using a construct representing the common region of spliced variants expressed as GST-fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50069364((R)-2-(1-((1-(3-(2-(6-butyl-5-methylpyridin-2-yl)v...)
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibition of [3H]LTD4 binding to LTD4 receptor of guinea pig lung membrane with human serum albumin (HSA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50280696(Sodium; (S)-3-{(S)-1-[3-(7-chloro-quinolin-2-ylmet...)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory concentration against [3H]Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50280695(Sodium; 2-[1-{3-[2-(7-chloro-quinolin-2-yl)-ethyl]...)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory concentration against [3H]Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1/2(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50216211(CHEMBL143597)
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50069373(2-(1-(((1R)-3-(2-(2-hydroxypropan-2-yl)phenyl)-1-(...)
Affinity DataIC50: 0.510nMAssay Description:In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50280699(3-[1-[3-(7-Chloro-quinolin-2-ylmethoxy)-phenyl]-3-...)
Affinity DataIC50: 0.520nMAssay Description:Inhibitory concentration against [3H]Leukotriene D4 binding to guinea-pig lung membranes was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50285683((1-{(R)-1-{3-[(E)-2-(2,3-Dichloro-thieno[3,2-b]pyr...)
Affinity DataIC50: 0.550nMAssay Description:Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50069372((1-{(R)-1-{3-[(E)-2-(6,6-Dimethyl-6,7-dihydro-5H-[...)
Affinity DataIC50: 0.560nMAssay Description:In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of DMSO differentiated human U937 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50280698(Sodium; 3-[1-[3-(7-chloro-quinolin-2-ylmethoxy)-ph...)
Affinity DataIC50: 0.560nMAssay Description:Inhibitory concentration against [3H]Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetDihydrofolate reductase(Rat)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50006906(CHEMBL23977 | 2-{4-[(2-Amino-4-oxo-3,4-dihydro-qui...)
Affinity DataKi:  0.580nMAssay Description:Compound was evaluated for the inhibition of partially purified rat liver Dihydrofolate reductase (DHFR) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50286254(3-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]...)
Affinity DataIC50: 0.580nMAssay Description:Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes (different expt)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1/2(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50069357([1-((R)-3-[2-(1-Hydroxy-1-methyl-ethyl)-phenyl]-1-...)
Affinity DataIC50: 0.580nMAssay Description:In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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