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TargetAryl hydrocarbon receptor(Mouse)
Palack£

Curated by ChEMBL
LigandPNGBDBM50506039(CHEMBL1324296 | US11891386, Compound 002)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]TCDD from mouse AhR expressed in mouse Hepa1c1c7 cells cytosol incubated for 2 hrs by competitive radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Mouse)
Palack£

Curated by ChEMBL
LigandPNGBDBM50605060(CHEMBL5198290 | US11891386, Compound 004)
Affinity DataKi:  88nMAssay Description:Displacement of [3H]TCDD from mouse AhR expressed in mouse Hepa1c1c7 cells cytosol incubated for 2 hrs by competitive radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNADPH oxidase 1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190499(CHEMBL3827985)
Affinity DataKi:  350nMAssay Description:Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Mouse)
Palack£

Curated by ChEMBL
LigandPNGBDBM50605061(CHEMBL5179114)
Affinity DataKi:  800nMAssay Description:Displacement of [3H]TCDD from mouse AhR expressed in mouse Hepa1c1c7 cells cytosol incubated for 2 hrs by competitive radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNADPH oxidase 4(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190499(CHEMBL3827985)
Affinity DataKi:  840nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190343(CHEMBL3827795)
Affinity DataKi:  880nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190331(CHEMBL3828176)
Affinity DataKi:  1.02E+3nMAssay Description:Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190390(CHEMBL3828444)
Affinity DataKi:  1.45E+3nMAssay Description:Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190343(CHEMBL3827795)
Affinity DataKi:  1.95E+3nMAssay Description:Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190331(CHEMBL3828176)
Affinity DataKi:  2.33E+3nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190497(CHEMBL3827227)
Affinity DataKi:  2.36E+3nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190330(CHEMBL3828737)
Affinity DataKi:  2.39E+3nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190328(CHEMBL3827342)
Affinity DataKi:  2.63E+3nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190390(CHEMBL3828444)
Affinity DataKi:  3.12E+3nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190328(CHEMBL3827342)
Affinity DataKi:  4.39E+3nMAssay Description:Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190347(CHEMBL3827481)
Affinity DataKi:  6.35E+3nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190498(CHEMBL3827096)
Affinity DataKi:  6.58E+3nMAssay Description:Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190497(CHEMBL3827227)
Affinity DataKi:  6.63E+3nMAssay Description:Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190498(CHEMBL3827096)
Affinity DataKi:  6.83E+3nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190347(CHEMBL3827481)
Affinity DataKi:  7.39E+3nMAssay Description:Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190503(CHEMBL3827569)
Affinity DataKi:  7.65E+3nMAssay Description:Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190391(CHEMBL3826995)
Affinity DataKi:  8.04E+3nMAssay Description:Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190330(CHEMBL3828737)
Affinity DataKi:  8.40E+3nMAssay Description:Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190503(CHEMBL3827569)
Affinity DataKi:  9.31E+3nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190346(CHEMBL3827497)
Affinity DataKi:  1.23E+4nMAssay Description:Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190391(CHEMBL3826995)
Affinity DataKi:  1.31E+4nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190344(CHEMBL3828498)
Affinity DataKi:  2.40E+4nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190348(CHEMBL3827421)
Affinity DataKi:  2.60E+4nMAssay Description:Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190329(CHEMBL3827065)
Affinity DataKi:  2.64E+4nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190341(CHEMBL3827688)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190342(CHEMBL3828713)
Affinity DataKi:  2.71E+4nMAssay Description:Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190345(CHEMBL3827574)
Affinity DataKi:  2.77E+4nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190329(CHEMBL3827065)
Affinity DataKi:  2.79E+4nMAssay Description:Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190345(CHEMBL3827574)
Affinity DataKi:  3.38E+4nMAssay Description:Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190327(CHEMBL3828285)
Affinity DataKi:  3.38E+4nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190327(CHEMBL3828285)
Affinity DataKi:  3.45E+4nMAssay Description:Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190342(CHEMBL3828713)
Affinity DataKi:  3.46E+4nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190346(CHEMBL3827497)
Affinity DataKi:  3.56E+4nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190348(CHEMBL3827421)
Affinity DataKi:  3.76E+4nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190344(CHEMBL3828498)
Affinity DataKi:  4.97E+4nMAssay Description:Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190341(CHEMBL3827688)
Affinity DataKi:  5.03E+4nMAssay Description:Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Human)
Incheon University Industry Academic Cooperation Foundation

US Patent
LigandPNGBDBM473585(US10844062, Example 21)
Affinity DataIC50:  4.10nMAssay Description:The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo™ kinase assay kit com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Lg Chem

US Patent
LigandPNGBDBM624845(US20230322706, Example 29)
Affinity DataIC50:  6.70nMAssay Description:1. Preparation of DGAT2 Expression Vector. In order to prepare the pBacPAK9-DGAT2, which is DGAT2 expression vector, the human DGAT2 gene amplified b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Lg Chem

US Patent
LigandPNGBDBM624843(US20230322706, Example 27 | US20230322706, Example...)
Affinity DataIC50:  7.40nMAssay Description:1. Preparation of DGAT2 Expression Vector. In order to prepare the pBacPAK9-DGAT2, which is DGAT2 expression vector, the human DGAT2 gene amplified b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170264(CHEMBL361931 | N-{4-[3-(4-tert-Butyl-benzyl)-thiou...)
Affinity DataIC50:  8.40nMAssay Description:Inhibitory effect on capsaicin (0.5 uM)-induced calcium uptake in rat DRG neurons upon incubation at RT for 10 minutesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Human)
Incheon University Industry Academic Cooperation Foundation

US Patent
LigandPNGBDBM473613(US10844062, Example 49)
Affinity DataIC50:  10nMAssay Description:The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo™ kinase assay kit com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
Lg Chem

US Patent
LigandPNGBDBM624819(US20230322706, Example 5)
Affinity DataIC50:  11nMAssay Description:1. Preparation of DGAT2 Expression Vector. In order to prepare the pBacPAK9-DGAT2, which is DGAT2 expression vector, the human DGAT2 gene amplified b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Incheon University Industry Academic Cooperation Foundation

US Patent
LigandPNGBDBM473190(US10844062, Example 1)
Affinity DataIC50:  11nMAssay Description:The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo™ kinase assay kit com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Incheon University Industry Academic Cooperation Foundation

US Patent
LigandPNGBDBM473640(US10844062, Example 76)
Affinity DataIC50:  11nMAssay Description:The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo™ kinase assay kit com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Incheon University Industry Academic Cooperation Foundation

US Patent
LigandPNGBDBM473594(US10844062, Example 30)
Affinity DataIC50:  11nMAssay Description:The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo™ kinase assay kit com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

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