Compile Data Set for Download or QSAR
Report error Found 41 with Last Name = 'koch' and Initial = 'th'
TargetEstrogen receptor beta(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50474781(CHEMBL19195)
Affinity DataIC50: 5nMAssay Description:Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50135908(CHEMBL146858 | Cyanonilutamide | 4-(4,4-Dimethyl-2...)
Affinity DataIC50: 6nMAssay Description:Inhibition of 1.0 nM [3H]mibolerone binding to human androgen receptor of PC3/AR cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50135908(CHEMBL146858 | Cyanonilutamide | 4-(4,4-Dimethyl-2...)
Affinity DataIC50: 6nMAssay Description:Inhibition of [3H]mibolerone binding to human Androgen receptor of PC3/AR Cell LysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50135912(5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]...)
Affinity DataIC50: 9nMAssay Description:Inhibition of [3H]mibolerone binding to human Androgen receptor of PC3/AR Cell LysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50135912(5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]...)
Affinity DataIC50: 9nMAssay Description:Inhibition of 1.0 nM [3H]mibolerone binding to human androgen receptor of PC3/AR cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target7-dehydrocholesterol reductase(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50411320(CHEMBL222694)
Affinity DataIC50: 30nMAssay Description:Growth inhibition of MDA-MB-231 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
Target7-dehydrocholesterol reductase(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50411320(CHEMBL222694)
Affinity DataIC50: 30nMAssay Description:Growth inhibition of MCF7 cells expressing ER and antiestrogen binding sitesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
Target7-dehydrocholesterol reductase(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50411320(CHEMBL222694)
Affinity DataIC50: 40nMAssay Description:Growth inhibition of MDA-MB-435 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50410198(CHEMBL2113036)
Affinity DataIC50: 49nMAssay Description:Inhibition of [3H]mibolerone binding to human Androgen receptor of PC3/AR Cell LysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50135914(5-{4-[3-(4-Cyano-3-trifluoromethyl-phenyl)-5,5-dim...)
Affinity DataIC50: 49nMAssay Description:Inhibition of 1.0 nM [3H]mibolerone binding to human androgen receptor of PC3/AR cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target7-dehydrocholesterol reductase(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50411319(CHEMBL266892)
Affinity DataIC50: 50nMAssay Description:Growth inhibition of MDA-MB-435 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
Target7-dehydrocholesterol reductase(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50411320(CHEMBL222694)
Affinity DataIC50: 60nMAssay Description:Growth inhibition of multidrug resistant MCF7/Adr cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50155877(Doxorubicin-Formaldehyde Conjugate | CHEMBL386437)
Affinity DataIC50: 63nMAssay Description:Inhibition of [3H]mibolerone binding to human Androgen receptor of PC3/AR Cell LysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target7-dehydrocholesterol reductase(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50411319(CHEMBL266892)
Affinity DataIC50: 70nMAssay Description:Growth inhibition of MCF7 cells expressing ER and antiestrogen binding sitesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50135910(5-(2-{2-[3-(4-Cyano-3-trifluoromethyl-phenyl)-5,5-...)
Affinity DataIC50: 77nMAssay Description:Inhibition of 1.0 nM [3H]mibolerone binding to human androgen receptor of PC3/AR cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50410197(CHEMBL2113034)
Affinity DataIC50: 77nMAssay Description:Inhibition of [3H]mibolerone binding to human Androgen receptor of PC3/AR Cell LysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target7-dehydrocholesterol reductase(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50411319(CHEMBL266892)
Affinity DataIC50: 80nMAssay Description:Growth inhibition of MDA-MB-231 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50155875(Doxorubicin-Formaldehyde Conjugate | CHEMBL264131)
Affinity DataIC50: 90nMAssay Description:Inhibition of [3H]mibolerone binding to human Androgen receptor of PC3/AR Cell LysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50409765(CHEMBL2112885)
Affinity DataIC50: 90nMAssay Description:Inhibition of 1.0 nM [3H]mibolerone binding to human androgen receptor of PC3/AR cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50474783(CHEMBL278308)
Affinity DataIC50: 150nMAssay Description:Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target7-dehydrocholesterol reductase(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM22984(Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...)
Affinity DataIC50: 150nMAssay Description:Growth inhibition of MDA-MB-435 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50474779(CHEMBL19481)
Affinity DataIC50: 150nMAssay Description:Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50131270(2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]prop...)
Affinity DataIC50: 154nMAssay Description:Inhibition of 1.0 nM [3H]mibolerone binding to human androgen receptor of PC3/AR cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50131270(2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]prop...)
Affinity DataIC50: 154nMAssay Description:Inhibition of [3H]mibolerone binding to human Androgen receptor of PC3/AR Cell LysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50474784(CHEMBL410193)
Affinity DataIC50: 200nMAssay Description:Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target7-dehydrocholesterol reductase(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM22984(Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...)
Affinity DataIC50: 200nMAssay Description:Growth inhibition of MCF7 cells expressing ER and antiestrogen binding sitesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50474782(CHEMBL19535)
Affinity DataIC50: 300nMAssay Description:Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50474780(CHEMBL266703)
Affinity DataIC50: 300nMAssay Description:Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target7-dehydrocholesterol reductase(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM22984(Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...)
Affinity DataIC50: 300nMAssay Description:Growth inhibition of MDA-MB-231 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50474785(CHEMBL266185)
Affinity DataIC50: 300nMAssay Description:Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50410196(CHEMBL2113032)
Affinity DataIC50: 332nMAssay Description:Inhibition of [3H]mibolerone binding to human Androgen receptor of PC3/AR Cell LysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50135911(5-[2-(2-{2-[3-(4-Cyano-3-trifluoromethyl-phenyl)-5...)
Affinity DataIC50: 332nMAssay Description:Inhibition of 1.0 nM [3H]mibolerone binding to human androgen receptor of PC3/AR cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50135915(5-{2-[4-(2-{2-[3-(4-Cyano-3-trifluoromethyl-phenyl...)
Affinity DataIC50: 346nMAssay Description:Inhibition of [3H]mibolerone binding to human Androgen receptor of PC3/AR Cell LysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50135915(5-{2-[4-(2-{2-[3-(4-Cyano-3-trifluoromethyl-phenyl...)
Affinity DataIC50: 346nMAssay Description:Inhibition of 1.0 nM [3H]mibolerone binding to human androgen receptor of PC3/AR cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50056900(2-Carbamoylphenol | 2-Carboxamidophenol | 2-Hydrox...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 1.0 nM [3H]mibolerone binding to human androgen receptor of PC3/AR cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50135909(5-[2-(4-{4-[3-(4-Cyano-3-trifluoromethyl-phenyl)-5...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 1.0 nM [3H]mibolerone binding to human androgen receptor of PC3/AR cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50135909(5-[2-(4-{4-[3-(4-Cyano-3-trifluoromethyl-phenyl)-5...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]mibolerone binding to human Androgen receptor of PC3/AR Cell LysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target7-dehydrocholesterol reductase(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50411319(CHEMBL266892)
Affinity DataIC50: 2.00E+3nMAssay Description:Growth inhibition of multidrug resistant MCF7/Adr cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
Target7-dehydrocholesterol reductase(Human)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM22984(Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Growth inhibition of multidrug resistant MCF7/Adr cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed