Compile Data Set for Download or QSAR
Report error Found 222 with Last Name = 'kosugi' and Initial = 'y'
TargetProtein O-GlcNAcase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50557164(CHEMBL4778870)
Affinity DataEC50:  450nMAssay Description:Inhibition of OGA in human SH-SY5Y cells assessed as increase in O-GIcNAcylated protein levels incubated for 48 hrs by in-cell Western assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataEC50:  0.0220nMAssay Description:Agonist activity at human MT1 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 30 mins by AlphaS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM103443(US8552037, 90)
Affinity DataEC50:  0.0150nMAssay Description:Agonist activity at human MT1 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 30 mins by AlphaS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMelatonin receptor type 1B(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataEC50:  0.850nMAssay Description:Agonist activity at human MT2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 30 mins by AlphaS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelatonin receptor type 1B(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM103443(US8552037, 90)
Affinity DataEC50:  0.510nMAssay Description:Agonist activity at human MT2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 30 mins by AlphaS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataEC50:  0.0260nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as decrease in forskolin-stimulated cAMP release after 30 mins by multilabel p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelatonin receptor type 1B(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50347588(CHEMBL1802025)
Affinity DataEC50:  0.530nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells assessed as decrease in forskolin-stimulated cAMP release after 30 mins by multilabel p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelatonin receptor type 1B(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataEC50:  0.820nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells assessed as decrease in forskolin-stimulated cAMP release after 30 mins by multilabel p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelatonin receptor type 1A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50347588(CHEMBL1802025)
Affinity DataEC50:  0.0210nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as decrease in forskolin-stimulated cAMP release after 30 mins by multilabel p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50447747(CHEMBL3113272)
Affinity DataIC50: 0.0250nMAssay Description:Apparent inhibition of human FAAH expressed in CHOK1 cells using AMCAA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50447748(CHEMBL3113271)
Affinity DataIC50: 0.0720nMAssay Description:Apparent inhibition of human FAAH expressed in CHOK1 cells using AMCAA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50447745(CHEMBL3113274)
Affinity DataIC50: 0.0800nMAssay Description:Apparent inhibition of human FAAH expressed in CHOK1 cells using AMCAA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50447747(CHEMBL3113272)
Affinity DataIC50: 0.170nMAssay Description:Apparent inhibition of rat FAAH using AMCAA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50447746(CHEMBL3113273)
Affinity DataIC50: 0.280nMAssay Description:Apparent inhibition of rat FAAH using AMCAA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50447745(CHEMBL3113274)
Affinity DataIC50: 0.340nMAssay Description:Apparent inhibition of rat FAAH using AMCAA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50447749(CHEMBL3113270)
Affinity DataIC50: 0.430nMAssay Description:Apparent inhibition of rat FAAH using AMCAA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50447746(CHEMBL3113273)
Affinity DataIC50: 0.720nMAssay Description:Apparent inhibition of human FAAH expressed in CHOK1 cells using AMCAA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50447749(CHEMBL3113270)
Affinity DataIC50: 1.10nMAssay Description:Apparent inhibition of human FAAH expressed in CHOK1 cells using AMCAA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50447748(CHEMBL3113271)
Affinity DataIC50: 1.20nMAssay Description:Apparent inhibition of rat FAAH using AMCAA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50425719(CHEMBL2316217)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant His-tagged cIAP1 protein BIR3 domain (250 to 350 amino acid residues) using biotinylated-Smac as substrate after over...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50447750(CHEMBL3113269)
Affinity DataIC50: 1.5nMAssay Description:Apparent inhibition of human FAAH expressed in CHOK1 cells using AMCAA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50425721(CHEMBL2311586)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human recombinant His-tagged cIAP1 protein BIR3 domain (250 to 350 amino acid residues) using biotinylated-Smac as substrate after over...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50447750(CHEMBL3113269)
Affinity DataIC50: 1.70nMAssay Description:Apparent inhibition of rat FAAH using AMCAA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50425728(CHEMBL2365533)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human recombinant His-tagged cIAP1 protein BIR3 domain (250 to 350 amino acid residues) using biotinylated-Smac as substrate after over...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50447751(CHEMBL3113268)
Affinity DataIC50: 2.20nMAssay Description:Apparent inhibition of human FAAH expressed in CHOK1 cells using AMCAA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50425722(CHEMBL2316215)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant His-tagged cIAP1 protein BIR3 domain (250 to 350 amino acid residues) using biotinylated-Smac as substrate after over...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50425725(CHEMBL2316224)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human recombinant His-tagged cIAP1 protein BIR3 domain (250 to 350 amino acid residues) using biotinylated-Smac as substrate after over...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50425730(CHEMBL2316219)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human recombinant His-tagged cIAP1 protein BIR3 domain (250 to 350 amino acid residues) using biotinylated-Smac as substrate after over...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50425724(CHEMBL2316213)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human recombinant His-tagged cIAP1 protein BIR3 domain (250 to 350 amino acid residues) using biotinylated-Smac as substrate after over...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50425723(CHEMBL2316214)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human recombinant His-tagged cIAP1 protein BIR3 domain (250 to 350 amino acid residues) using biotinylated-Smac as substrate after over...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50425727(CHEMBL2316222)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant His-tagged cIAP1 protein BIR3 domain (250 to 350 amino acid residues) using biotinylated-Smac as substrate after over...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50234480(CHEMBL4069551)
Affinity DataIC50: 4.10nMAssay Description:Displacement of ovine [125-I]-CRF from human CRF1 receptor expressed in CHO cell membranes preincubated for 1 hr followed by [125I]-CRF addition meas...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50447751(CHEMBL3113268)
Affinity DataIC50: 4.30nMAssay Description:Apparent inhibition of rat FAAH using AMCAA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50460165(CHEMBL4225254)
Affinity DataIC50: 4.40nMAssay Description:Antagonist activity at human CRF1 receptor expressed in CHO cells assessed as inhibition of human CRF-stimulated cAMP accumulation after 4 hrs by luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50425720(CHEMBL2316216)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human recombinant His-tagged cIAP1 protein BIR3 domain (250 to 350 amino acid residues) using biotinylated-Smac as substrate after over...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50460165(CHEMBL4225254)
Affinity DataIC50: 7.10nMAssay Description:Displacement of ovine [125-I]-CRF from human CRF1 receptor expressed in CHO cell membranes after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50234477(CHEMBL4087369)
Affinity DataIC50: 7.40nMAssay Description:Displacement of ovine [125-I]-CRF from human CRF1 receptor expressed in CHO cell membranes preincubated for 1 hr followed by [125I]-CRF addition meas...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50425726(CHEMBL2316223)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human recombinant His-tagged cIAP1 protein BIR3 domain (250 to 350 amino acid residues) using biotinylated-Smac as substrate after over...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50234487(CHEMBL4070898)
Affinity DataIC50: 7.90nMAssay Description:Displacement of ovine [125-I]-CRF from human CRF1 receptor expressed in CHO cell membranes after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50234482(CHEMBL4096045)
Affinity DataIC50: 8.60nMAssay Description:Displacement of ovine [125-I]-CRF from human CRF1 receptor expressed in CHO cell membranes preincubated for 1 hr followed by [125I]-CRF addition meas...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50161867(CHEMBL3793277)
Affinity DataIC50: 9.5nMAssay Description:Displacement of ovine [125-I]-CRF from human CRF1 receptor expressed in CHO cell membranes after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50161832(CHEMBL3792517)
Affinity DataIC50: 9.5nMAssay Description:Displacement of ovine [125-I]-CRF from human CRF1 receptor expressed in CHO cell membranes preincubated for 1 hr followed by [125I]-CRF addition meas...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50460180(CHEMBL4224887)
Affinity DataIC50: 11nMAssay Description:Displacement of ovine [125-I]-CRF from human CRF1 receptor expressed in CHO cell membranes after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50447753(CHEMBL3113266)
Affinity DataIC50: 12nMAssay Description:Apparent inhibition of rat FAAH using AMCAA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50447754(CHEMBL3113265)
Affinity DataIC50: 13nMAssay Description:Apparent inhibition of rat FAAH using AMCAA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50425731(CHEMBL2316218)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant His-tagged cIAP1 protein BIR3 domain (250 to 350 amino acid residues) using biotinylated-Smac as substrate after over...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50234478(CHEMBL4101653)
Affinity DataIC50: 15nMAssay Description:Displacement of ovine [125-I]-CRF from human CRF1 receptor expressed in CHO cell membranes preincubated for 1 hr followed by [125I]-CRF addition meas...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116105(3-(6-(dimethylamino)-4-methylpyridin-3-yl)-2,5-dim...)
Affinity DataIC50: 17nMAssay Description:Displacement of ovine [125-I]-CRF from human CRF1 receptor expressed in CHO cell membranes preincubated for 1 hr followed by [125I]-CRF addition meas...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50460172(CHEMBL4225516)
Affinity DataIC50: 18nMAssay Description:Displacement of ovine [125-I]-CRF from human CRF1 receptor expressed in CHO cell membranes after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein O-GlcNAcase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50557163(CHEMBL4781640)
Affinity DataIC50: 18nMAssay Description:Inhibition of full-length human OGA expressed in Expi293 (HEK293) cells using 4-methylumbelliferyl-N-acetyl-beta-D-glucosaminide dihydrate as fluorog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 222 total ) | Next | Last >>
Jump to: