Compile Data Set for Download or QSAR
Report error Found 608 with Last Name = 'kung' and Initial = 'hf'
TargetD(1A) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50016792(SK-83566 | 8-Bromo-3-methyl-5-phenyl-2,3,4,5-tetra...)
Affinity DataKd:  2.30nMAssay Description:In vitro binding affinity to the rat striatal homogenate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50016795(CHEMBL287504 | 3-Methyl-5-phenyl-2,3,4,5-tetrahydr...)
Affinity DataKd:  197nMAssay Description:In vitro binding affinity to the rat striatal homogenate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50016794(CHEMBL34170 | 8-Chloro-5-(4-iodo-phenyl)-3-methyl-...)
Affinity DataKd:  1.40nMAssay Description:In vitro binding affinity towards Dopamine receptor D1 by displacing [125I]FISCH radioligand in rat striatal homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50173647(4-[(E)-2-(4-Methylamino-phenyl)-vinyl]-phenol | [3...)
Affinity DataKd:  2.40nMAssay Description:Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50038276(7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro...)
Affinity DataKd:  0.480nMAssay Description:Binding affinity was tested against dopamine receptor D3 in rat striatal membrane homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50020222(CHEMBL285755 | 7-Dipropylamino-5,6,7,8-tetrahydro-...)
Affinity DataKd:  0.670nMAssay Description:Tested for binding affinity against dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50043603(7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro...)
Affinity DataKd:  0.0500nMAssay Description:Binding affinity was tested against dopamine receptor D3 in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50038276(7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro...)
Affinity DataKd:  0.130nMAssay Description:Binding affinity was tested against dopamine receptor D3 in the absence of NaClMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM86708(CHEMBL31354 | CHEMBL514874 | NSC_104911 | CAS_1467...)
Affinity DataKd:  0.100nMAssay Description:In vitro binding affinity for 5-hydroxytryptamine 1A receptor was determined by measuring specific inhibition of [125I]-binding to rat hippocampal me...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50005118(3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-h...)
Affinity DataKd:  1.10nMAssay Description:Affinity constant of compound was evaluated in rat striatum tissue preparation.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50005118(3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-h...)
Affinity DataKd:  7.10nMAssay Description:Affinity constant of compound was evaluated in human brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM11638(N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sul...)
Affinity DataKd:  1.5nMAssay Description:Affinity constant of compound was evaluated in rat striatum tissue preparation.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50020704(CHEMBL8475 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-h...)
Affinity DataKd:  0.430nMAssay Description:Affinity constant of compound was evaluated in rat striatum tissue preparation.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50004813(8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-methyl-1-phe...)
Affinity DataKd:  0.0970nMAssay Description:Affinity constant of compound was evaluated in human brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50007518(3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmet...)
Affinity DataKd:  0.170nMAssay Description:Affinity constant of compound was evaluated in rat striatum tissue preparation.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50012964(CHEMBL8945 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-h...)
Affinity DataKd:  31nMAssay Description:Affinity constant of compound was evaluated in rat striatum tissue preparation.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50004813(8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-methyl-1-phe...)
Affinity DataKd:  0.0970nMAssay Description:Evaluated in vivo for the affinity towards Dopamine receptor D2 of rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50040082(N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-methoxy-5-sulf...)
Affinity DataKd:  1.5nMAssay Description:Evaluated in vivo for the affinity towards Dopamine receptor D2 of rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50012964(CHEMBL8945 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-h...)
Affinity DataKd:  31nMAssay Description:Evaluated in vivo for the affinity towards Dopamine receptor D2 of rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50007518(3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmet...)
Affinity DataKd:  0.170nMAssay Description:Evaluated in vivo for the affinity towards Dopamine receptor D2 of rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50012961(N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo...)
Affinity DataKd:  0.430nMAssay Description:Evaluated in vivo for the affinity towards Dopamine receptor D2 of rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50012966(CHEMBL49405 | 8-[4-(4-Fluoro-2-iodo-phenyl)-4-oxo-...)
Affinity DataKd:  0.25nMAssay Description:Evaluated in vivo for the affinity towards Dopamine receptor D2 of rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50012967(N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy...)
Affinity DataKd:  3nMAssay Description:Evaluated in vivo for the affinity towards Dopamine receptor D2 of rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50012968(CHEMBL50154 | 4-Azido-N-(1-benzyl-piperidin-4-yl)-...)
Affinity DataKd:  14nMAssay Description:Evaluated in vivo for the affinity towards Dopamine receptor D2 of rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50007170(CHEMBL26533 | Adamantane-1-carboxylic acid {4-[4-(...)
Affinity DataKd:  0.400nMAssay Description:Inhibition of binding of [125I]-8-OH-PIPAT ligand to 5-hydroxytryptamine 1A receptor of rat hippocampal homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50035508(CHEMBL29027 | p-MPPI | 4-Iodo-N-{2-[4-(2-methoxy-p...)
Affinity DataKd:  0.300nMAssay Description:The binding of [125I]MPPI ligand to 5-hydroxytryptamine 1A receptor of rat hippocampal homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50386904(CHEMBL2048526)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to DATMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50544832(CHEMBL4636677)
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]MIP-1095 from PSMA in human PC3-PIP cells after 1 hr by gamma counter analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 2nMAssay Description:In vitro inhibition of azido-[125I]-IPAPP (0.25 nM) binding to 5-HT1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 2nMAssay Description:In vitro inhibition of [125I]IPAPP (0.25 nM) binding to 5-HT1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50544834(CHEMBL4636963)
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]MIP-1095 from PSMA in human PC3-PIP cells after 1 hr by gamma counter analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM86708(CHEMBL31354 | CHEMBL514874 | NSC_104911 | CAS_1467...)
Affinity DataIC50: 2.20nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1A receptor of rat hippocampal homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM86708(CHEMBL31354 | CHEMBL514874 | NSC_104911 | CAS_1467...)
Affinity DataIC50: 2.20nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor using [125I](R)-(+)-trans-8-OH-PIPAT as radioligand in rat hippocampal homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50020582(CHEMBL284820 | Dipropyl-(1,2,3,4-tetrahydro-naphth...)
Affinity DataIC50: 2.40nMAssay Description:In vitro inhibition of [125I]IPAPP (2.5 nM) binding to 5-hydroxytryptamine 1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50544835(CHEMBL4649277)
Affinity DataIC50: 2.60nMAssay Description:Displacement of [125I]MIP-1095 from PSMA in human PC3-PIP cells after 1 hr by gamma counter analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50265783((S)-2-(3-((S)-1-Carboxy-5-(3-(4-iodophenyl)ureido)...)
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]MIP-1095 from PSMA in human PC3-PIP cells after 1 hr by gamma counter analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50020580(CHEMBL359124 | 1-[2-(3-Azido-phenyl)-ethyl]-4-(3-t...)
Affinity DataIC50: 3.10nMAssay Description:In vitro inhibition of [3H]5-HT (2 nM) binding to 5-hydroxytryptamine 1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50544836(CHEMBL4639640)
Affinity DataIC50: 3.5nMAssay Description:Displacement of [125I]MIP-1095 from PSMA in human PC3-PIP cells after 1 hr by gamma counter analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50544837(CHEMBL4648379)
Affinity DataIC50: 4.70nMAssay Description:Displacement of [125I]MIP-1095 from PSMA in human PC3-PIP cells after 1 hr by gamma counter analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50020580(CHEMBL359124 | 1-[2-(3-Azido-phenyl)-ethyl]-4-(3-t...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibition of [3H]5-HT (2 nM) binding to 5-HT1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 5.60nMAssay Description:In vitro inhibition of [3H]5-HT (2 nM) binding to 5-HT1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 6nMAssay Description:In vitro inhibition of [3H]5-HT (2 nM) binding to 5-hydroxytryptamine 1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50020579(CHEMBL423045 | 3-{2-[4-(3-Trifluoromethyl-phenyl)-...)
Affinity DataIC50: 8.10nMAssay Description:In vitro inhibition of [3H]5-HT (2 nM) binding to 5-HT1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50020579(CHEMBL423045 | 3-{2-[4-(3-Trifluoromethyl-phenyl)-...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of [3H]5-HT (2 nM) binding to 5-hydroxytryptamine 1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50544833(Vipivotide tetraxetan | PSMA-617)
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]MIP-1095 from PSMA in human PC3-PIP cells after 1 hr by gamma counter analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50544838(CHEMBL4635514)
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]MIP-1095 from PSMA in human PC3-PIP cells after 1 hr by gamma counter analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50047471(N-tert-Butyl-3-[4-(2-methoxy-phenyl)-piperazin-1-y...)
Affinity DataIC50: 15nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor using [125I](R)-(+)-trans-8-OH-PIPAT as radioligand in rat hippocampal homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50020578(CHEMBL155615 | 1-[2-(4-Azido-3-iodo-phenyl)-ethyl]...)
Affinity DataIC50: 35nMAssay Description:In vitro inhibition of [3H]5-HT (2 nM) binding to 5-HT1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50020581(CHEMBL153174 | 2-Iodo-4-{2-[4-(3-trifluoromethyl-p...)
Affinity DataIC50: 38nMAssay Description:In vitro inhibition of [3H]DPAT (1 nM) binding to 5-HT1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50020581(CHEMBL153174 | 2-Iodo-4-{2-[4-(3-trifluoromethyl-p...)
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of [3H]5-HT (2 nM) binding to 5-hydroxytryptamine 1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 608 total ) | Next | Last >>
Jump to: