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Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204672(CHEMBL3961059)
Affinity DataEC50:  457nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582598(CHEMBL5074880)
Affinity DataEC50:  759nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582599(CHEMBL5081379)
Affinity DataEC50:  1.18E+3nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204678(CHEMBL3931889)
Affinity DataEC50:  1.15E+3nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582603(CHEMBL5091373)
Affinity DataEC50:  72nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582604(CHEMBL5094234)
Affinity DataEC50:  182nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582605(CHEMBL5093342)
Affinity DataEC50:  1.05E+3nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582607(CHEMBL5074190)
Affinity DataEC50:  83nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582608(CHEMBL5084249)
Affinity DataEC50:  1.86E+3nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582609(CHEMBL5094493)
Affinity DataEC50:  1.38E+3nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582610(CHEMBL5077293)
Affinity DataEC50:  91nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582611(CHEMBL5083607)
Affinity DataEC50:  562nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  9.30nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458526(CHEMBL4205349 | US20240199555, Reference E55888)
Affinity DataEC50:  83nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204672(CHEMBL3961059)
Affinity DataEC50:  460nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582598(CHEMBL5074880)
Affinity DataEC50:  770nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582599(CHEMBL5081379)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204678(CHEMBL3931889)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582603(CHEMBL5091373)
Affinity DataEC50:  73nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582604(CHEMBL5094234)
Affinity DataEC50:  180nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582605(CHEMBL5093342)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582607(CHEMBL5074190)
Affinity DataEC50:  84nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582608(CHEMBL5084249)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582609(CHEMBL5094493)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582610(CHEMBL5077293)
Affinity DataEC50:  92nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582611(CHEMBL5083607)
Affinity DataEC50:  560nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  9.33nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458526(CHEMBL4205349 | US20240199555, Reference E55888)
Affinity DataEC50:  83nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204672(CHEMBL3961059)
Affinity DataEC50:  148nMAssay Description:Agonist activity at 5-HT7R (unknown origin) transfected in HEK293 cells expressing tTA-dependent luciferase reporter and beta arrestin 2-TEV fusion g...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204678(CHEMBL3931889)
Affinity DataEC50:  479nMAssay Description:Agonist activity at 5-HT7R (unknown origin) transfected in HEK293 cells expressing tTA-dependent luciferase reporter and beta arrestin 2-TEV fusion g...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582603(CHEMBL5091373)
Affinity DataEC50:  71nMAssay Description:Agonist activity at 5-HT7R (unknown origin) transfected in HEK293 cells expressing tTA-dependent luciferase reporter and beta arrestin 2-TEV fusion g...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582607(CHEMBL5074190)
Affinity DataEC50:  56nMAssay Description:Agonist activity at 5-HT7R (unknown origin) transfected in HEK293 cells expressing tTA-dependent luciferase reporter and beta arrestin 2-TEV fusion g...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582610(CHEMBL5077293)
Affinity DataEC50:  76nMAssay Description:Agonist activity at 5-HT7R (unknown origin) transfected in HEK293 cells expressing tTA-dependent luciferase reporter and beta arrestin 2-TEV fusion g...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582611(CHEMBL5083607)
Affinity DataEC50:  646nMAssay Description:Agonist activity at 5-HT7R (unknown origin) transfected in HEK293 cells expressing tTA-dependent luciferase reporter and beta arrestin 2-TEV fusion g...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  112nMAssay Description:Agonist activity at 5-HT7R (unknown origin) transfected in HEK293 cells expressing tTA-dependent luciferase reporter and beta arrestin 2-TEV fusion g...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458526(CHEMBL4205349 | US20240199555, Reference E55888)
Affinity DataEC50:  21nMAssay Description:Agonist activity at 5-HT7R (unknown origin) transfected in HEK293 cells expressing tTA-dependent luciferase reporter and beta arrestin 2-TEV fusion g...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204672(CHEMBL3961059)
Affinity DataEC50:  150nMAssay Description:Agonist activity at 5-HT7R (unknown origin) transfected in HEK293 cells expressing tTA-dependent luciferase reporter and beta arrestin 2-TEV fusion g...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204678(CHEMBL3931889)
Affinity DataEC50:  480nMAssay Description:Agonist activity at 5-HT7R (unknown origin) transfected in HEK293 cells expressing tTA-dependent luciferase reporter and beta arrestin 2-TEV fusion g...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582603(CHEMBL5091373)
Affinity DataEC50:  71nMAssay Description:Agonist activity at 5-HT7R (unknown origin) transfected in HEK293 cells expressing tTA-dependent luciferase reporter and beta arrestin 2-TEV fusion g...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582607(CHEMBL5074190)
Affinity DataEC50:  56nMAssay Description:Agonist activity at 5-HT7R (unknown origin) transfected in HEK293 cells expressing tTA-dependent luciferase reporter and beta arrestin 2-TEV fusion g...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582610(CHEMBL5077293)
Affinity DataEC50:  75nMAssay Description:Agonist activity at 5-HT7R (unknown origin) transfected in HEK293 cells expressing tTA-dependent luciferase reporter and beta arrestin 2-TEV fusion g...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582611(CHEMBL5083607)
Affinity DataEC50:  650nMAssay Description:Agonist activity at 5-HT7R (unknown origin) transfected in HEK293 cells expressing tTA-dependent luciferase reporter and beta arrestin 2-TEV fusion g...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  110nMAssay Description:Agonist activity at 5-HT7R (unknown origin) transfected in HEK293 cells expressing tTA-dependent luciferase reporter and beta arrestin 2-TEV fusion g...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458526(CHEMBL4205349 | US20240199555, Reference E55888)
Affinity DataEC50:  21nMAssay Description:Agonist activity at 5-HT7R (unknown origin) transfected in HEK293 cells expressing tTA-dependent luciferase reporter and beta arrestin 2-TEV fusion g...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50098551((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)
Affinity DataIC50: 0.930nMAssay Description:Antagonist activity at human 5-HT7 receptor expressed in HEK293 cells assessed as reduction in cAMP accumulation incubated for 30 mins by microplate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50098551((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)
Affinity DataIC50: 0.930nMAssay Description:Antagonist activity at human 5-HT7 receptor expressed in HEK293 cells assessed as reduction in cAMP accumulation incubated for 30 mins by microplate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573235(CHEMBL4877603)
Affinity DataIC50: 686nMAssay Description:Antagonist activity at human 5-HT7 receptor expressed in HEK293 cells assessed as reduction in cAMP accumulation incubated for 30 mins by microplate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573235(CHEMBL4877603)
Affinity DataIC50: 692nMAssay Description:Antagonist activity at human 5-HT7 receptor expressed in HEK293 cells assessed as reduction in cAMP accumulation incubated for 30 mins by microplate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573249(CHEMBL4858338)
Affinity DataIC50: 888nMAssay Description:Antagonist activity at human 5-HT7 receptor expressed in HEK293 cells assessed as reduction in cAMP accumulation incubated for 30 mins by microplate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573249(CHEMBL4858338)
Affinity DataIC50: 891nMAssay Description:Antagonist activity at human 5-HT7 receptor expressed in HEK293 cells assessed as reduction in cAMP accumulation incubated for 30 mins by microplate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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