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TargetPeroxisome proliferator-activated receptor alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297873(2-(4-(3-phenoxypropoxy)-phenylthio)hexanoic acid |...)
Affinity DataEC50:  290nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297874(2-(4-(3-(o-tolyloxy)propoxy)phenylthio)hexanoic ac...)
Affinity DataEC50:  250nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297875(2-(4-(3-(m-tolyloxy)propoxy)phenylthio)hexanoic ac...)
Affinity DataEC50:  90nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297876(2-(4-(3-(p-tolyloxy)propoxy)phenylthio)hexanoic ac...)
Affinity DataEC50:  85nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297877(2-(4-(3-(3,4-dimethylphenoxy)propoxy)phenylthio)he...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297878(2-(4-(3-(2,3-dimethylphenoxy)propoxy)phenylthio)he...)
Affinity DataEC50:  56nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297879((R)-2-(4-(3-(2,3-dimethylphenoxy)propoxy)phenylthi...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297880((S)-2-(4-(3-(2,3-dimethylphenoxy)propoxy)phenylthi...)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297881(2-(4-(3-(5,6,7,8-tetrahydronaphthalen-1-yloxy)prop...)
Affinity DataEC50:  190nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297882(2-(4-(3-(2-methoxyphenoxy)propoxy)phenylthio)hexan...)
Affinity DataEC50:  550nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297883(2-(4-(3-(3-methoxyphenoxy)propoxy)phenylthio)hexan...)
Affinity DataEC50:  49nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297884(2-(4-(3-(2-isopropylphenoxy)propoxy)phenylthio)hex...)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297885(2-(4-(3-(3-isopropylphenoxy)propoxy)phenylthio)hex...)
Affinity DataEC50:  150nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297886(2-(4-(3-(3-(trifluoromethyl)phenoxy)propoxy)phenyl...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297887(2-(4-(3-(4-chloro-3-(trifluoromethyl)phenoxy)propo...)
Affinity DataEC50:  390nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297888(2-(4-(3-(biphenyl-4-yloxy)propoxy)phenylthio)hexan...)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297889(2-(4-(3-(quinolin-6-yloxy)propoxy)phenylthio)hexan...)
Affinity DataEC50:  220nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297890(2-(4-(3-(2,3-dimethylphenoxy)propoxy)phenylthio)ac...)
Affinity DataEC50:  600nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297891(3-(4-(3-(2,3-dimethylphenoxy)propoxy)phenyl)propan...)
Affinity DataEC50:  1.38E+4nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297892(2-(4-(3-(2,3-dimethylphenoxy)propoxy)benzyl)hexano...)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297873(2-(4-(3-phenoxypropoxy)-phenylthio)hexanoic acid |...)
Affinity DataEC50:  2.60E+3nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297874(2-(4-(3-(o-tolyloxy)propoxy)phenylthio)hexanoic ac...)
Affinity DataEC50:  2.30E+3nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297875(2-(4-(3-(m-tolyloxy)propoxy)phenylthio)hexanoic ac...)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297876(2-(4-(3-(p-tolyloxy)propoxy)phenylthio)hexanoic ac...)
Affinity DataEC50:  930nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297877(2-(4-(3-(3,4-dimethylphenoxy)propoxy)phenylthio)he...)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297878(2-(4-(3-(2,3-dimethylphenoxy)propoxy)phenylthio)he...)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297879((R)-2-(4-(3-(2,3-dimethylphenoxy)propoxy)phenylthi...)
Affinity DataEC50:  3.90E+3nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297882(2-(4-(3-(2-methoxyphenoxy)propoxy)phenylthio)hexan...)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297883(2-(4-(3-(3-methoxyphenoxy)propoxy)phenylthio)hexan...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297884(2-(4-(3-(2-isopropylphenoxy)propoxy)phenylthio)hex...)
Affinity DataEC50:  4.10E+3nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297885(2-(4-(3-(3-isopropylphenoxy)propoxy)phenylthio)hex...)
Affinity DataEC50:  5.30E+3nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297886(2-(4-(3-(3-(trifluoromethyl)phenoxy)propoxy)phenyl...)
Affinity DataEC50:  4.60E+3nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297887(2-(4-(3-(4-chloro-3-(trifluoromethyl)phenoxy)propo...)
Affinity DataEC50:  7.80E+3nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297888(2-(4-(3-(biphenyl-4-yloxy)propoxy)phenylthio)hexan...)
Affinity DataEC50:  540nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297889(2-(4-(3-(quinolin-6-yloxy)propoxy)phenylthio)hexan...)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297890(2-(4-(3-(2,3-dimethylphenoxy)propoxy)phenylthio)ac...)
Affinity DataEC50:  3.80E+3nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297891(3-(4-(3-(2,3-dimethylphenoxy)propoxy)phenyl)propan...)
Affinity DataEC50:  1.57E+4nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297892(2-(4-(3-(2,3-dimethylphenoxy)propoxy)benzyl)hexano...)
Affinity DataEC50:  4.20E+3nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297880((S)-2-(4-(3-(2,3-dimethylphenoxy)propoxy)phenylthi...)
Affinity DataEC50:  9.90E+3nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297881(2-(4-(3-(5,6,7,8-tetrahydronaphthalen-1-yloxy)prop...)
Affinity DataEC50:  8.10E+3nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297890(2-(4-(3-(2,3-dimethylphenoxy)propoxy)phenylthio)ac...)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at human PPARbeta expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297891(3-(4-(3-(2,3-dimethylphenoxy)propoxy)phenyl)propan...)
Affinity DataEC50:  1.12E+4nMAssay Description:Agonist activity at human PPARbeta expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50006805(CHEMBL29097 | 3-(3-(tert-butylthio)-1-(4-chloroben...)
Affinity DataIC50: 90nMAssay Description:Inhibition of 5-lipoxygenase in A23187-stimulated human polymorphonuclear leukocytes using arachidonic acid as substrate incubated 15 mins prior to s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50443839(CHEMBL3094410)
Affinity DataIC50: 200nMAssay Description:Inhibition of 5-lipoxygenase in A23187-stimulated human polymorphonuclear leukocytes using arachidonic acid as substrate incubated 15 mins prior to s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50443842(CHEMBL3094426)
Affinity DataIC50: 200nMAssay Description:Inhibition of 5-lipoxygenase in A23187-stimulated human polymorphonuclear leukocytes using arachidonic acid as substrate incubated 15 mins prior to s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50443828(CHEMBL3094412)
Affinity DataIC50: 200nMAssay Description:Inhibition of 5-lipoxygenase in A23187-stimulated human polymorphonuclear leukocytes using arachidonic acid as substrate incubated 15 mins prior to s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50443831(CHEMBL3091499)
Affinity DataIC50: 200nMAssay Description:Inhibition of 5-lipoxygenase in A23187-stimulated human polymorphonuclear leukocytes using arachidonic acid as substrate incubated 15 mins prior to s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50443821(CHEMBL3094419)
Affinity DataIC50: 300nMAssay Description:Inhibition of mPGES-1 from human A549 cell microsomal membranes using PGH2 as substrate incubated 15 mins prior to substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50443826(CHEMBL3094414)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate incubated 5 to 10 mins prior to...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50443828(CHEMBL3094412)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate incubated 5 to 10 mins prior to...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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