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Report error Found 359 with Last Name = 'langgård' and Initial = 'm'
LigandPNGBDBM142416(US8927738, 2-[2-(2-Furan-3-yl-1H-imidazol-4-yl)-et...)
Affinity DataIC50: 0.270nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
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LigandPNGBDBM31596(substituted pyrazole, 13)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human PDE10A (amino acids 14 to 779) using [3H]-labelled cyclic nucleotide as substrate after 1 hr b beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
LigandPNGBDBM50398017(CHEMBL2180411 | US9018217, 5,8-Dimethyl-2-[2-(1-me...)
Affinity DataIC50: 0.320nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
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LigandPNGBDBM50398017(CHEMBL2180411 | US9018217, 5,8-Dimethyl-2-[2-(1-me...)
Affinity DataIC50: 0.320nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
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LigandPNGBDBM142410(US8927738, 5,8-Dimethyl-2-[2-(2-thiophen-2-yl-1H-i...)
Affinity DataIC50: 0.340nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
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LigandPNGBDBM142414(US8927738, 5,8-Dimethyl-2-[2-(2-thiophen-2-yl-1H-i...)
Affinity DataIC50: 0.400nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
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LigandPNGBDBM142412(US8927738, 2-[2-(2-Furan-2-yl-1H-imidazol-4-yl)-et...)
Affinity DataIC50: 0.620nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
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LigandPNGBDBM142415(US8927738, 5,8-Dimethyl-2-[2-(2-thiazol-2-yl-1H-im...)
Affinity DataIC50: 0.630nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
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LigandPNGBDBM142413(US8927738, 2-[2-(2-Furan-3-yl-1H-imidazol-4-yl)-et...)
Affinity DataIC50: 0.650nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
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LigandPNGBDBM47287(US9018217, 5,7-Dimethyl-2-[2-(4-phenyl-1-propyl-1H...)
Affinity DataIC50: 0.690nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
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LigandPNGBDBM47287(US9018217, 5,7-Dimethyl-2-[2-(4-phenyl-1-propyl-1H...)
Affinity DataIC50: 0.690nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
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LigandPNGBDBM142409(US8927738, 2-[2-(2-Furan-2-yl-1-methyl-1H-imidazol...)
Affinity DataIC50: 0.75nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
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LigandPNGBDBM156359(US9018217, 8-Ethyl-5-methyl-2-[2-(1-methyl-4-pheny...)
Affinity DataIC50: 0.930nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
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LigandPNGBDBM156359(US9018217, 8-Ethyl-5-methyl-2-[2-(1-methyl-4-pheny...)
Affinity DataIC50: 0.930nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
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LigandPNGBDBM142417(US8927738, 2-[2-(2-Furan-2-yl-1H-imidazol-4-yl)-et...)
Affinity DataIC50: 0.970nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
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LigandPNGBDBM50397979(US8927738, 5,8-Dimethyl-2-[2-(1-methyl-2-thiophen-...)
Affinity DataIC50: 1nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
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LigandPNGBDBM47296(US9018217, 8-Ethyl-5-methyl-2-(2-(1-methyl-4-pheny...)
Affinity DataIC50: 1.10nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
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LigandPNGBDBM142406(US8927738, 2-[2-(2-Furan-2-yl-1-methyl-1H-imidazol...)
Affinity DataIC50: 1.10nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
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LigandPNGBDBM47296(US9018217, 8-Ethyl-5-methyl-2-(2-(1-methyl-4-pheny...)
Affinity DataIC50: 1.10nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
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LigandPNGBDBM299447(US9592230, 5-Methyl-2-{2-[4-phenyl-1-(2-piperidin-...)
Affinity DataIC50: 1.30nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
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LigandPNGBDBM156347(US9018217, 2-[2-(1-Isobutyl-4-phenyl-1H-imidazol-2...)
Affinity DataIC50: 1.30nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
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LigandPNGBDBM47283(US9018217, 5-Methyl-2-(2-[4-phenyl-1-(2-piperidin-...)
Affinity DataIC50: 1.30nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
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LigandPNGBDBM156347(US9018217, 2-[2-(1-Isobutyl-4-phenyl-1H-imidazol-2...)
Affinity DataIC50: 1.30nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
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LigandPNGBDBM156350(US9018217, 5,7-Dimethyl-2-{2-[1-(2-morpholin-4-yl-...)
Affinity DataIC50: 1.40nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
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LigandPNGBDBM156350(US9018217, 5,7-Dimethyl-2-{2-[1-(2-morpholin-4-yl-...)
Affinity DataIC50: 1.40nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
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LigandPNGBDBM156337(US9018217, 2-[2-(1-Isobutyl-4-phenyl-1H-imidazol-2...)
Affinity DataIC50: 1.60nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
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LigandPNGBDBM142411(US8927738, 5,8-Dimethyl-2-[2-(2-thiazol-2-yl-1H-im...)
Affinity DataIC50: 1.60nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
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LigandPNGBDBM156337(US9018217, 2-[2-(1-Isobutyl-4-phenyl-1H-imidazol-2...)
Affinity DataIC50: 1.60nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
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LigandPNGBDBM50398014(CHEMBL2180414 | US9018217, 5,8-Dimethyl-2-[2-(1-me...)
Affinity DataIC50: 1.80nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
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LigandPNGBDBM50398014(CHEMBL2180414 | US9018217, 5,8-Dimethyl-2-[2-(1-me...)
Affinity DataIC50: 1.80nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
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LigandPNGBDBM156352(US9018217, 8-methoxy-5-methyl-2-(2-(1-methyl-4-phe...)
Affinity DataIC50: 2.5nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
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LigandPNGBDBM156352(US9018217, 8-methoxy-5-methyl-2-(2-(1-methyl-4-phe...)
Affinity DataIC50: 2.5nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
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LigandPNGBDBM31592(PF-2545920 | substituted pyrazole, 9 | US9138494, ...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
LigandPNGBDBM156346(US9018217, 5,7-Dimethyl-2-{2-[4-phenyl-1-(2-piperi...)
Affinity DataIC50: 2.70nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
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LigandPNGBDBM156346(US9018217, 5,7-Dimethyl-2-{2-[4-phenyl-1-(2-piperi...)
Affinity DataIC50: 2.70nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
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LigandPNGBDBM156333(US9018217, 5-Methyl-2-[2-(4-phenyl-1H-imidazol-2-y...)
Affinity DataIC50: 2.80nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
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LigandPNGBDBM47278(US9018217, 1-Methyl-3-(2-[2-[2-(5-methyl-[1,2,4]tr...)
Affinity DataIC50: 2.80nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
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LigandPNGBDBM156342(US9018217, 5-Methyl-2-[2-(1-methyl-4-phenyl-1H-imi...)
Affinity DataIC50: 2.80nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
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LigandPNGBDBM47278(US9018217, 1-Methyl-3-(2-[2-[2-(5-methyl-[1,2,4]tr...)
Affinity DataIC50: 2.80nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
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LigandPNGBDBM156333(US9018217, 5-Methyl-2-[2-(4-phenyl-1H-imidazol-2-y...)
Affinity DataIC50: 2.80nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
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LigandPNGBDBM156342(US9018217, 5-Methyl-2-[2-(1-methyl-4-phenyl-1H-imi...)
Affinity DataIC50: 2.80nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
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LigandPNGBDBM142404(US8927738, 5,8-Dimethyl-2-[2-(2-thiazol-5-yl-1H-im...)
Affinity DataIC50: 3.10nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
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LigandPNGBDBM156348(US9018217, 2-[2-(1-Isopropyl-4-phenyl-1H-imidazol-...)
Affinity DataIC50: 3.40nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
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LigandPNGBDBM156348(US9018217, 2-[2-(1-Isopropyl-4-phenyl-1H-imidazol-...)
Affinity DataIC50: 3.40nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
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LigandPNGBDBM142407(US8927738, 5,8-Dimethyl-2-[2-(2-thiazol-4-yl-1H-im...)
Affinity DataIC50: 3.5nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
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LigandPNGBDBM142408(US8927738, 5,8-Dimethyl-2-[2-(2-thiazol-4-yl-1H-im...)
Affinity DataIC50: 3.5nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
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LigandPNGBDBM142418(US8927738, 5,8-Dimethyl-2-{2-[1-methyl-2-(5-methyl...)
Affinity DataIC50: 3.5nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
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LigandPNGBDBM156354(US9018217, 5-Methyl-2-[2-(1-methyl-4-phenyl-1H-imi...)
Affinity DataIC50: 3.60nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
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LigandPNGBDBM156354(US9018217, 5-Methyl-2-[2-(1-methyl-4-phenyl-1H-imi...)
Affinity DataIC50: 3.60nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
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LigandPNGBDBM156334(US9018217, 2-(1-Isobutyl-4-phenyl-1H-imidazol-2-yl...)
Affinity DataIC50: 4.20nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
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