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TargetAdenosine deaminase(Bovine)
Universita Di Pisa

LigandPNGBDBM28377(2-nonyl-2H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one | ...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The activity of ADA was determined spectrophotometrically by monitoring the change in absorbance at 262 nm, due to the deamination of adenosine catal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine deaminase(Bovine)
Universita Di Pisa

LigandPNGBDBM28378(2-decyl-2H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one | ...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The activity of ADA was determined spectrophotometrically by monitoring the change in absorbance at 262 nm, due to the deamination of adenosine catal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine deaminase(Bovine)
Universita Di Pisa

LigandPNGBDBM28379(2-undecyl-2H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one ...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The activity of ADA was determined spectrophotometrically by monitoring the change in absorbance at 262 nm, due to the deamination of adenosine catal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Consiglio Nazionale Delle Ricerche

LigandPNGBDBM28759(CHEMBL191275 | (2S)-3-phenyl-2-(4-phenylphenoxy)pr...)
Affinity DataEC50:  480nMAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Consiglio Nazionale Delle Ricerche

LigandPNGBDBM28760((2R)-3-phenyl-2-(4-phenylphenoxy)propanoic acid | ...)
Affinity DataEC50:  5.93E+3nMAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Consiglio Nazionale Delle Ricerche

LigandPNGBDBM28681(cid_5281055 | [3H]rosiglitazone | CHEMBL121 | ROSI...)
Affinity DataEC50:  40nMAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Consiglio Nazionale Delle Ricerche

LigandPNGBDBM28759(CHEMBL191275 | (2S)-3-phenyl-2-(4-phenylphenoxy)pr...)
Affinity DataEC50:  220nMAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Consiglio Nazionale Delle Ricerche

LigandPNGBDBM24566(JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...)
Affinity DataEC50:  1.62E+3nMAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor alpha(Mouse)
Consiglio Nazionale Delle Ricerche

LigandPNGBDBM28759(CHEMBL191275 | (2S)-3-phenyl-2-(4-phenylphenoxy)pr...)
Affinity DataEC50:  260nMAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Mouse)
Consiglio Nazionale Delle Ricerche

LigandPNGBDBM24566(JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...)
Affinity DataEC50:  40nMAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor alpha(Human)
Consiglio Nazionale Delle Ricerche

LigandPNGBDBM28760((2R)-3-phenyl-2-(4-phenylphenoxy)propanoic acid | ...)
Affinity DataAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Mouse)
Consiglio Nazionale Delle Ricerche

LigandPNGBDBM28760((2R)-3-phenyl-2-(4-phenylphenoxy)propanoic acid | ...)
Affinity DataAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Consiglio Nazionale Delle Ricerche

LigandPNGBDBM28681(cid_5281055 | [3H]rosiglitazone | CHEMBL121 | ROSI...)
Affinity DataKd:  14.8nM EC50:  3.80nMpH: 7.5 T: 2°CAssay Description:Kd values were obtained by incubating His-PPARgamma-LBD with biotinylated peptide, europium-labeled anti-histidine antibody, and allophycocyanin-labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Consiglio Nazionale Delle Ricerche

LigandPNGBDBM28762((2R)-2-(4-{2-[1,3-benzoxazol-2-yl(heptyl)amino]eth...)
Affinity DataKd:  685nM EC50:  73.3nMpH: 7.5 T: 2°CAssay Description:Kd values were obtained by incubating His-PPARgamma-LBD with biotinylated peptide, europium-labeled anti-histidine antibody, and allophycocyanin-labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
Consiglio Nazionale Delle Ricerche

LigandPNGBDBM28763((2S)-2-(4-{2-[1,3-benzoxazol-2-yl(heptyl)amino]eth...)
Affinity DataKd:  1.98E+3nM EC50:  593nMpH: 7.5 T: 2°CAssay Description:Kd values were obtained by incubating His-PPARgamma-LBD with biotinylated peptide, europium-labeled anti-histidine antibody, and allophycocyanin-labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50247454(CHEMBL4088238)
Affinity DataEC50:  541nMAssay Description:Agonist activity at recombinant human adenosine A1 receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity in p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50247449(CHEMBL4068787)
Affinity DataEC50:  134nMAssay Description:Agonist activity at recombinant human adenosine A1 receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity in p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50247446(CHEMBL4078360)
Affinity DataEC50:  5.57E+3nMAssay Description:Agonist activity at recombinant human adenosine A1 receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity in p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50247453(CHEMBL4103712)
Affinity DataEC50:  54nMAssay Description:Agonist activity at recombinant human adenosine A1 receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity in p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50247455(CHEMBL4098408)
Affinity DataEC50:  56nMAssay Description:Agonist activity at recombinant human adenosine A1 receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity in p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50247457(CHEMBL4079464)
Affinity DataEC50:  1.28E+4nMAssay Description:Agonist activity at recombinant human adenosine A2B receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity in ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50247455(CHEMBL4098408)
Affinity DataEC50:  3.74E+3nMAssay Description:Agonist activity at recombinant human adenosine A2B receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity in ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50247452(CHEMBL4080383)
Affinity DataEC50: >6.00E+4nMAssay Description:Agonist activity at recombinant human adenosine A2B receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity in ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50247454(CHEMBL4088238)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at recombinant human adenosine A2B receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity in ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50247450(CHEMBL4095344)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at recombinant human adenosine A2B receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity in ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50247449(CHEMBL4068787)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at recombinant human adenosine A2B receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity in ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50247458(CHEMBL4067452)
Affinity DataEC50: >6.00E+4nMAssay Description:Agonist activity at recombinant human adenosine A2B receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity in ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50247447(CHEMBL4102630)
Affinity DataEC50: >6.00E+4nMAssay Description:Agonist activity at recombinant human adenosine A2B receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity in ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50247456(CHEMBL4079314)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at recombinant human adenosine A2B receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity in ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50247445(CHEMBL4097343)
Affinity DataEC50: >6.00E+4nMAssay Description:Agonist activity at recombinant human adenosine A2B receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity in ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50247444(CHEMBL4087198)
Affinity DataEC50: >6.00E+4nMAssay Description:Agonist activity at recombinant human adenosine A2B receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity in ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50247456(CHEMBL4079314)
Affinity DataEC50:  577nMAssay Description:Agonist activity at recombinant human adenosine A1 receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity in p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50247457(CHEMBL4079464)
Affinity DataEC50:  140nMAssay Description:Agonist activity at recombinant human adenosine A1 receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity in p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50247453(CHEMBL4103712)
Affinity DataEC50:  2.00E+4nMAssay Description:Agonist activity at recombinant human adenosine A2B receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity in ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50247451(CHEMBL4059994)
Affinity DataEC50: >6.00E+4nMAssay Description:Agonist activity at recombinant human adenosine A2B receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity in ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50247448(CHEMBL4094884)
Affinity DataEC50: >6.00E+4nMAssay Description:Agonist activity at recombinant human adenosine A2B receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity in ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50247446(CHEMBL4078360)
Affinity DataEC50: >6.00E+4nMAssay Description:Agonist activity at recombinant human adenosine A2B receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity in ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50247443(CHEMBL4105044)
Affinity DataEC50: >6.00E+4nMAssay Description:Agonist activity at recombinant human adenosine A2B receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity in ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50078426(CHEMBL3414940)
Affinity DataEC50:  7.70nMAssay Description:Agonist activity at recombinant human adenosine A1 receptor expressed in CHO cell membranes assessed as inhibition of forskolin-stimulated adenylyl c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50078427(CHEMBL3414941)
Affinity DataEC50:  7.20nMAssay Description:Agonist activity at recombinant human adenosine A1 receptor expressed in CHO cell membranes assessed as inhibition of forskolin-stimulated adenylyl c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50266662(CHEMBL4087306)
Affinity DataEC50:  7.70nMAssay Description:Agonist activity at recombinant human adenosine A1 receptor expressed in CHO cell membranes assessed as inhibition of forskolin-stimulated adenylyl c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50266644(CHEMBL4076003)
Affinity DataEC50:  552nMAssay Description:Agonist activity at recombinant human adenosine A1 receptor expressed in CHO cell membranes assessed as inhibition of forskolin-stimulated adenylyl c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50266645(CHEMBL4086325)
Affinity DataEC50:  341nMAssay Description:Agonist activity at recombinant human adenosine A1 receptor expressed in CHO cell membranes assessed as inhibition of forskolin-stimulated adenylyl c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50266646(CHEMBL4089741)
Affinity DataEC50:  208nMAssay Description:Agonist activity at recombinant human adenosine A1 receptor expressed in CHO cell membranes assessed as inhibition of forskolin-stimulated adenylyl c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50266648(CHEMBL4097468)
Affinity DataEC50:  147nMAssay Description:Agonist activity at recombinant human adenosine A1 receptor expressed in CHO cell membranes assessed as inhibition of forskolin-stimulated adenylyl c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50266663(CHEMBL4079433)
Affinity DataEC50:  239nMAssay Description:Agonist activity at recombinant human adenosine A1 receptor expressed in CHO cell membranes assessed as inhibition of forskolin-stimulated adenylyl c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50266650(CHEMBL4098377)
Affinity DataEC50:  116nMAssay Description:Agonist activity at recombinant human adenosine A1 receptor expressed in CHO cell membranes assessed as inhibition of forskolin-stimulated adenylyl c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50266651(CHEMBL4081876)
Affinity DataEC50:  45nMAssay Description:Agonist activity at recombinant human adenosine A1 receptor expressed in CHO cell membranes assessed as inhibition of forskolin-stimulated adenylyl c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50266664(CHEMBL4059961)
Affinity DataEC50:  73nMAssay Description:Agonist activity at recombinant human adenosine A1 receptor expressed in CHO cell membranes assessed as inhibition of forskolin-stimulated adenylyl c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50266653(CHEMBL4102750)
Affinity DataEC50:  230nMAssay Description:Agonist activity at recombinant human adenosine A1 receptor expressed in CHO cell membranes assessed as inhibition of forskolin-stimulated adenylyl c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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