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Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50458532(CHEMBL4216782)
Affinity DataKi:  0.470nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50139355(2-(6-Phenylpyridin-2-ylthio)-N,N-dimethylethan-ami...)
Affinity DataKi:  0.600nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50004891(CHEMBL2164327)
Affinity DataKi:  0.600nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50055575(CHEMBL3321794)
Affinity DataKi:  0.700nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50354493(CHEMBL409662)
Affinity DataKi:  0.790nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50510971(CHEMBL4442472)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]5-HT from recombinant human 5-HT7 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50098551((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)
Affinity DataKi:  1.30nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Guinea pig)
Université

Curated by ChEMBL
LigandPNGBDBM50293279(1-Methyl-5-[(1-propylpiperidin-4-yl)methyloxy]-pyr...)
Affinity DataKi:  1.74nMAssay Description:Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50150417(CHEMBL182322 | N-[2-(4-Fluoro-phenoxy)-ethyl]-N''-...)
Affinity DataKi:  2nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50510970(CHEMBL4521657)
Affinity DataKi:  2nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50116963(2a-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)butyl)...)
Affinity DataKi:  2.10nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50458526(CHEMBL4205349 | US20240199555, Reference E55888)
Affinity DataKi:  2.5nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50395192(CHEMBL2164336)
Affinity DataKi:  2.60nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 3A(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50108392((3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-I...)
Affinity DataKi:  2.80nMAssay Description:Binding affinity at 5HT3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50150405(CHEMBL182797 | N-(2-Phenoxy-ethyl)-N''-(1-phenyl-e...)
Affinity DataKi:  3nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50151310(CHEMBL3302600)
Affinity DataKi:  3nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi:  3.20nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50510968(CHEMBL4533865)
Affinity DataKi:  3.5nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM78940(METHIOTHEPIN | MLS000859918 | Methiothepin mesylat...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]5-HT from recombinant human 5-HT7 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50510967(CHEMBL3139441)
Affinity DataKi:  4.5nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50170158(1-(2-Methoxy-phenyl)-4-(1-o-tolyl-1H-pyrrol-3-ylme...)
Affinity DataKi:  4.70nMAssay Description:Binding affinity against Human 5-HT7R expressed in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50170158(1-(2-Methoxy-phenyl)-4-(1-o-tolyl-1H-pyrrol-3-ylme...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]LSD from human 5HT7 in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM82087(2-(5-methoxy-1H-indol-3-yl)ethanamine | 5-MT | 5-M...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]5-HT from recombinant human 5-HT7 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Guinea pig)
Université

Curated by ChEMBL
LigandPNGBDBM50413548(CHEMBL512679)
Affinity DataKi:  5.37nMAssay Description:Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50170156(2-(3-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-1...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]LSD from human 5HT7 in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50170156(2-(3-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-1...)
Affinity DataKi:  5.40nMAssay Description:Binding affinity against Human 5-HT7R expressed in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50210122(CHEMBL234881 | [2-(2',6'-dimethyl-biphenyl-3-yl)-e...)
Affinity DataKi:  6.20nMAssay Description:Displacement of [3H]LSD from human 5HT7 in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM30704((phenylmethyl) N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a...)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]5-HT from recombinant human 5-HT7 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Guinea pig)
Université

Curated by ChEMBL
LigandPNGBDBM50413547(CHEMBL448702)
Affinity DataKi:  6.46nMAssay Description:Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50458523(JNJ-18038683)
Affinity DataKi:  6.5nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50220503(CHEMBL348890)
Affinity DataKi:  7.20nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50210124(2-(2'-methyl-biphenyl-3-yl)-ethylamine | CHEMBL234...)
Affinity DataKi:  7.5nMAssay Description:Displacement of [3H]LSD from human 5HT7 in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50210123(CHEMBL395870 | N,N-dimethyl-2-(2'-methylbiphenyl-3...)
Affinity DataKi:  7.60nMAssay Description:Displacement of [3H]LSD from human 5HT7 in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataKi:  7.90nMAssay Description:Displacement of [3H]5-HT from recombinant human 5-HT7 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50210126(CHEMBL232792 | [2-(2'-methoxy-biphenyl-3-yl)-ethyl...)
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H]LSD from human 5HT7 in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Guinea pig)
Université

Curated by ChEMBL
LigandPNGBDBM50413546(CHEMBL513254)
Affinity DataKi:  8.51nMAssay Description:Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50210125(CHEMBL232791 | [2-(2',6'-dimethoxy-biphenyl-3-yl)-...)
Affinity DataKi:  8.60nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50210125(CHEMBL232791 | [2-(2',6'-dimethoxy-biphenyl-3-yl)-...)
Affinity DataKi:  8.60nMAssay Description:Displacement of [3H]LSD from human 5HT7 in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Guinea pig)
Université

Curated by ChEMBL
LigandPNGBDBM50413545(CHEMBL469575)
Affinity DataKi:  8.71nMAssay Description:Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Guinea pig)
Université

Curated by ChEMBL
LigandPNGBDBM50413544(CHEMBL511794)
Affinity DataKi:  9.55nMAssay Description:Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50170158(1-(2-Methoxy-phenyl)-4-(1-o-tolyl-1H-pyrrol-3-ylme...)
Affinity DataKi:  9.90nMAssay Description:Binding affinity to rat 5HT1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50170158(1-(2-Methoxy-phenyl)-4-(1-o-tolyl-1H-pyrrol-3-ylme...)
Affinity DataKi:  9.90nMAssay Description:Binding affinity against rat 5-HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Guinea pig)
Université

Curated by ChEMBL
LigandPNGBDBM50413543(CHEMBL472481)
Affinity DataKi:  11.2nMAssay Description:Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Guinea pig)
Université

Curated by ChEMBL
LigandPNGBDBM50413542(CHEMBL469582)
Affinity DataKi:  11.8nMAssay Description:Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Guinea pig)
Université

Curated by ChEMBL
LigandPNGBDBM50413541(CHEMBL469593)
Affinity DataKi:  12.9nMAssay Description:Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50139355(2-(6-Phenylpyridin-2-ylthio)-N,N-dimethylethan-ami...)
Affinity DataKi:  16nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Guinea pig)
Université

Curated by ChEMBL
LigandPNGBDBM50413540(CHEMBL471662)
Affinity DataKi:  16.2nMAssay Description:Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Guinea pig)
Université

Curated by ChEMBL
LigandPNGBDBM50413539(CHEMBL450595)
Affinity DataKi:  16.2nMAssay Description:Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50170159(2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-p...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]LSD from human 5HT7 in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50170159(2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-p...)
Affinity DataKi:  18nMAssay Description:Binding affinity against Human 5-HT7R expressed in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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