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TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614895(US20230271937, Example A7-54 | US20230271937, Exam...)
Affinity DataEC50:  0.600nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614836(US20230271937, Example A7-16 | US20230271937, Exam...)
Affinity DataEC50:  25nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614876(US20230271937, Example A7-35 | A7-35 2-(4-(((6-(cy...)
Affinity DataEC50:  310nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614893(US20230271937, Example A7-52 | A7-52 2-(4-(((6-(cy...)
Affinity DataEC50:  42nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50526408(CHEMBL4586446)
Affinity DataEC50:  306nMAssay Description:Agonist activity at human RXFP3 expressed in human CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 1.5 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614818(US20230271937, Example A7-6-1 | US20230271937, Exa...)
Affinity DataEC50:  49nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614836(US20230271937, Example A7-16 | US20230271937, Exam...)
Affinity DataEC50:  19nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCannabinoid receptor 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50132717(Isopropyl dodecylfluorophosphonate | isopropyl dod...)
Affinity DataEC50:  500nMAssay Description:Agonist activity at CB1 receptor in mouse brain membrane assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614880(US20230271937, Example A7-39 | US20230271937, Exam...)
Affinity DataEC50:  37nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614887(US20230271937, Example A7-46 | A7-46 2-(4-(((6-((4...)
Affinity DataEC50: >1.00E+3nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614958(US20230271937, Example E6-1 | Synthesis of 2-(4-am...)
Affinity DataEC50:  150nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614877(US20230271937, Example A7-36 | US20230271937, Exam...)
Affinity DataEC50:  670nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614881(US20230271937, Example A7-40 | A7-40 rac-2-((3R,4R...)
Affinity DataEC50:  5.5nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614832(US20230271937, Example A7-14-2 | A7-14-2)
Affinity DataEC50:  21nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614960(US20230271937, Example F2-06)
Affinity DataEC50:  350nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50580995(CHEMBL5087582)
Affinity DataEC50:  7.69E+3nMAssay Description:Agonist activity at human RXFP3 expressed in human CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 1.5 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614936(US20230271937, Example B4-2-1-1 | B4-2-1-1 2-(4-((...)
Affinity DataEC50:  7.5nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614809(US20230271937, Example A7-1 | US20230271937, Examp...)
Affinity DataEC50:  1.30nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614908(US20230271937, Example A7-65 | A7-65 rac-2-((3R,4R...)
Affinity DataEC50:  5.80nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614910(US20230271937, Example A7-66-2 | A7-66-2)
Affinity DataEC50:  88nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614942(US20230271937, Example D5-2-1-1 | D5-2-1-1 rel-2-(...)
Affinity DataEC50:  1.20nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCannabinoid receptor 1(Human)
University of Aberdeen

Curated by ChEMBL
LigandPNGBDBM50513131(CHEMBL4582487)
Affinity DataEC50:  342nMAssay Description:Positive allosteric modulation of human CB1 receptor expressed in CHOK1 cells assessed as increase in CP55940-induced beta-arrestin recruitment prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614833(US20230271937, Example A7-15 | A7-15 rac-2-((3R,4R...)
Affinity DataEC50:  160nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614911(US20230271937, Example A7-67)
Affinity DataEC50:  43nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50581003(CHEMBL5084431)
Affinity DataEC50:  70nMAssay Description:Agonist activity at human RXFP3 expressed in human CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 1.5 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614813(US20230271937, Example A7-3-1 | A7-3-1 rel-(R)-2-(...)
Affinity DataEC50:  44nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614931(US20230271937, Example A7-87 | A7-87 2-(4-(1-((6-(...)
Affinity DataEC50:  181nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAdenosine receptor A3(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50088428((1R,2R,3S,4R,5S)-4-[2-Chloro-6-(3-iodo-benzylamino...)
Affinity DataEC50:  0.670nMAssay Description:Stimulation of [35S]GTP-gamma-S, against human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50580997(CHEMBL5093979)
Affinity DataEC50:  3.95E+3nMAssay Description:Agonist activity at human RXFP3 expressed in human CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 1.5 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614874(US20230271937, Example A7-32 | A7-32 rac-2-((3R,4R...)
Affinity DataEC50:  34nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614917(US20230271937, Example A7-73 | A7-73 rac-2-((3R,4R...)
Affinity DataEC50:  99nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50580992(CHEMBL5077014)
Affinity DataEC50:  253nMAssay Description:Agonist activity at human RXFP3 expressed in human CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 1.5 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50581006(CHEMBL5076246)
Affinity DataEC50:  56nMAssay Description:Agonist activity at human RXFP3 expressed in human CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 1.5 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614850(US20230271937, Example A7-21 | A7-21 rac-2-((3R,4R...)
Affinity DataEC50:  9.30nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614938(US20230271937, Example C4-1-1 | C4-1-1 2-(4-(((6-(...)
Affinity DataEC50:  5.30nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614855(US20230271937, Example A7-22-2 | A7-22-2)
Affinity DataEC50:  3.40nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614875(US20230271937, Example A7-34 | A7-34 2-(4-(((6-(cy...)
Affinity DataEC50:  90nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614918(US20230271937, Example A7-74 | A7-74 rac-2-((3R,4R...)
Affinity DataEC50:  12nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCannabinoid receptor 1(Human)
University of Aberdeen

Curated by ChEMBL
LigandPNGBDBM50513124(CHEMBL4483556)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human CB1 receptor expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 30 mins by PathHunt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50581010(CHEMBL5072593)
Affinity DataEC50:  7.70nMAssay Description:Agonist activity at human RXFP3 expressed in human CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 1.5 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50581008(CHEMBL5078386)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human RXFP3 expressed in human CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 1.5 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Aberdeen

Curated by ChEMBL
LigandPNGBDBM50513132(CHEMBL4435270)
Affinity DataEC50:  301nMAssay Description:Positive allosteric modulation of human CB1 receptor expressed in CHOK1 cells assessed as increase in CP55940-induced beta-arrestin recruitment prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50580999(CHEMBL5089400)
Affinity DataEC50:  224nMAssay Description:Agonist activity at human RXFP3 expressed in human CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 1.5 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50581017(CHEMBL5081158)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human RXFP3 expressed in human CHO-K1 cells assessed as beta arrestin-2 recruitment measured after 4 hrs by beta-galactosidase ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614867(US20230271937, Example A7-28 | A7-28 rac-2-((3R,4R...)
Affinity DataEC50:  42nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50581009(CHEMBL5094670)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human RXFP3 expressed in human CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 1.5 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614847(US20230271937, Example A7-20 | A7-20 rac-2-((3R,4R...)
Affinity DataEC50:  26nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614867(US20230271937, Example A7-28 | A7-28 rac-2-((3R,4R...)
Affinity DataEC50:  20.5nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50581015(CHEMBL5094396)
Affinity DataEC50:  53nMAssay Description:Agonist activity at human RXFP3 expressed in human CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 1.5 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614877(US20230271937, Example A7-36 | US20230271937, Exam...)
Affinity DataEC50:  860nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

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