Compile Data Set for Download or QSAR
Report error Found 40 with Last Name = 'liimatta' and Initial = 'mb'
LigandPNGBDBM25077(6-{[(5Z)-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-y...)
Affinity DataIC50: 1.92nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM25073(4-[2-(4-bromophenyl)ethyl]-6-{[(5Z)-4-oxo-2-sulfan...)
Affinity DataIC50: 2.34nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM25061(4-[(4-tert-butylphenyl)methyl]-6-{[(5Z)-4-oxo-2-su...)
Affinity DataIC50: 2.42nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM25066(4-[(3,4-dimethylphenyl)methyl]-6-{[(5Z)-4-oxo-2-su...)
Affinity DataIC50: 2.59nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM25068(4-[2-(3,5-dimethylphenyl)ethyl]-6-{[(5Z)-4-oxo-2-s...)
Affinity DataIC50: 2.65nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM25080(4-[2-(3-methoxyphenyl)ethyl]-6-{[(5Z)-4-oxo-2-sulf...)
Affinity DataIC50: 2.66nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM25069(4-[2-(3,5-dimethoxyphenyl)ethyl]-6-{[(5Z)-4-oxo-2-...)
Affinity DataIC50: 2.79nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM25074(4-[2-(3-chlorophenyl)ethyl]-6-{[(5Z)-4-oxo-2-sulfa...)
Affinity DataIC50: 4.27nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM25078(4-[2-(2,4-dichlorophenyl)ethyl]-6-{[(5Z)-4-oxo-2-s...)
Affinity DataIC50: 4.28nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM25075(4-[2-(3,4-dichlorophenyl)ethyl]-6-{[(5Z)-4-oxo-2-s...)
Affinity DataIC50: 4.36nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM25070(4-[2-(4-chlorophenyl)ethyl]-6-{[(5Z)-4-oxo-2-sulfa...)
Affinity DataIC50: 4.76nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM25081(4-[2-(3,4-difluorophenyl)ethyl]-6-{[(5Z)-4-oxo-2-s...)
Affinity DataIC50: 4.84nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM25079(4-[2-(3-methylphenyl)ethyl]-6-{[(5Z)-4-oxo-2-sulfa...)
Affinity DataIC50: 4.96nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM25071(4-[2-(4-methoxyphenyl)ethyl]-6-{[(5Z)-4-oxo-2-sulf...)
Affinity DataIC50: 6.57nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM25062(4-[(4-chlorophenyl)methyl]-6-{[(5Z)-4-oxo-2-sulfan...)
Affinity DataIC50: 7.16nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335377(N-Pyridazin-3-yl-4-(3-{[5-(trifluoromethyl)pyridin...)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of His-tagged human FAAH N-terminal transmembrane-deleted truncated form expressed in Escherichia coli preincubated for 60 mins before ole...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50335377(N-Pyridazin-3-yl-4-(3-{[5-(trifluoromethyl)pyridin...)
Affinity DataIC50: 7.40nMAssay Description:Irreversible inhibition of His-tagged rat FAAH N-terminal transmembrane-deleted truncated form expressed in Escherichia coli preincubated for 60 mins...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM25072(4-[2-(4-methylphenyl)ethyl]-6-{[(5Z)-4-oxo-2-sulfa...)
Affinity DataIC50: 8.83nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM15234(NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...)
Affinity DataIC50: 19nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM25059(4-benzyl-6-{[(5Z)-4-oxo-2-sulfanylidene-1,3-thiazo...)
Affinity DataIC50: 23nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM25067(6-{[(5Z)-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-y...)
Affinity DataIC50: 24.5nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM25064(6-{[(5Z)-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-y...)
Affinity DataIC50: 27.5nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM25060(4-[(4-methylphenyl)methyl]-6-{[(5Z)-4-oxo-2-sulfan...)
Affinity DataIC50: 29.5nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM25076(4-[2-(4-tert-butylphenyl)ethyl]-6-{[(5Z)-4-oxo-2-s...)
Affinity DataIC50: 33.2nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM25063(4-[(3-oxo-6-{[(5Z)-4-oxo-2-sulfanylidene-1,3-thiaz...)
Affinity DataIC50: 36.1nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM25065(4-[(3-methylphenyl)methyl]-6-{[(5Z)-4-oxo-2-sulfan...)
Affinity DataIC50: 43.7nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM25058((5Z)-5-[(3-hydroxy-5-methoxyphenyl)methylidene]-2-...)
Affinity DataIC50: 77.7nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335380(N-Pyridin-3-yl-4-(3-{[5-(trifluoromethyl)pyridin-2...)
Affinity DataIC50: 800nMAssay Description:Inhibition of CYP3A4 uisng testosterone substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335380(N-Pyridin-3-yl-4-(3-{[5-(trifluoromethyl)pyridin-2...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335379(N-(6-Methylpyridin-3-yl)-4-(3-{[5-(trifluoromethyl...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM12915(CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...)
Affinity DataIC50: 1.72E+3nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335379(N-(6-Methylpyridin-3-yl)-4-(3-{[5-(trifluoromethyl...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CYP3A4 uisng testosterone substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335380(N-Pyridin-3-yl-4-(3-{[5-(trifluoromethyl)pyridin-2...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of CYP3A4 uisng midazolam substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335379(N-(6-Methylpyridin-3-yl)-4-(3-{[5-(trifluoromethyl...)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of CYP3A4 uisng midazolam substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335377(N-Pyridazin-3-yl-4-(3-{[5-(trifluoromethyl)pyridin...)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335378(N-Pyrazin-2-yl-4-(3-{[5-(trifluoromethyl)pyridin-2...)
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of CYP3A4 uisng testosterone substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335378(N-Pyrazin-2-yl-4-(3-{[5-(trifluoromethyl)pyridin-2...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335377(N-Pyridazin-3-yl-4-(3-{[5-(trifluoromethyl)pyridin...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 uisng testosterone substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335377(N-Pyridazin-3-yl-4-(3-{[5-(trifluoromethyl)pyridin...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 uisng midazolam substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335378(N-Pyrazin-2-yl-4-(3-{[5-(trifluoromethyl)pyridin-2...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 uisng midazolam substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed