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TargetGlutamate receptor 1(Mouse)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50107595(2-Amino-3-(2,4-dioxo-2,3,4,5,6,7-hexahydro-cyclope...)
Affinity DataEC50:  2.49E+4nMAssay Description:The potency at recombinant rat AMPA-R was measured on GluR1 receptor expressed in Xenopus Laevis oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 2(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50107595(2-Amino-3-(2,4-dioxo-2,3,4,5,6,7-hexahydro-cyclope...)
Affinity DataEC50:  1.39E+4nMAssay Description:The potency at recombinant rat AMPA-R was measured on receptor Ionotropic glutamate receptor AMPA 2 expressed in Xenopus Laevis oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 3(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50107595(2-Amino-3-(2,4-dioxo-2,3,4,5,6,7-hexahydro-cyclope...)
Affinity DataEC50:  2.24E+5nMAssay Description:The potency at recombinant rat AMPA-R was measured on Ionotropic glutamate receptor AMPA 3 expressed in Xenopus Laevis oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 4(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50107595(2-Amino-3-(2,4-dioxo-2,3,4,5,6,7-hexahydro-cyclope...)
Affinity DataEC50:  3.43E+4nMAssay Description:The potency at recombinant rat AMPA-R was measured on GluR4 receptor expressed in Xenopus Laevis oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 3(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50017244(CHEMBL73698 | 2-Amino-3-(4-bromo-3-hydroxy-isoxazo...)
Affinity DataEC50:  2.00E+5nMAssay Description:Effective concentration of compound was determined for electrophysiological properties on Ionotropic glutamate receptor AMPA 3 (GluR3) using rat cort...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 4(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50017244(CHEMBL73698 | 2-Amino-3-(4-bromo-3-hydroxy-isoxazo...)
Affinity DataEC50:  3.80E+4nMAssay Description:Effective concentration of compound was determined for electrophysiological properties on Ionotropic glutamate receptor AMPA 4 (GluR4) using rat cort...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Mouse)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50002370((RS)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)-p...)
Affinity DataEC50:  8.70E+3nMAssay Description:Effective concentration of compound was determined for electrophysiological properties on Metabotropic glutamate receptor 1 using rat cortical slice ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 2(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50017244(CHEMBL73698 | 2-Amino-3-(4-bromo-3-hydroxy-isoxazo...)
Affinity DataEC50:  5.40E+3nMAssay Description:Effective concentration of compound was determined for electrophysiological properties on Ionotropic glutamate receptor AMPA 2 (GluR2) using rat cort...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Mouse)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataEC50:  4.70E+3nMAssay Description:Effective concentration of compound was determined for electrophysiological properties on Ionotropic glutamate receptor AMPA 1 (GluR1) using rat cort...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Mouse)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50017244(CHEMBL73698 | 2-Amino-3-(4-bromo-3-hydroxy-isoxazo...)
Affinity DataEC50:  1.40E+4nMAssay Description:Effective concentration of compound was determined for electrophysiological properties on Metabotropic glutamate receptor 1 using rat cortical slice ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 3(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50002370((RS)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)-p...)
Affinity DataEC50:  1.40E+3nMAssay Description:Effective concentration of compound was determined for electrophysiological properties on Ionotropic glutamate receptor AMPA 3 (GluR3) using rat cort...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 2(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataEC50:  1.70E+3nMAssay Description:Effective concentration of compound was determined for electrophysiological properties on Ionotropic glutamate receptor AMPA 2 (GluR2) using rat cort...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 4(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataEC50:  1.30E+6nMAssay Description:Effective concentration of compound was determined for electrophysiological properties on Ionotropic glutamate receptor AMPA 4 (GluR4) using rat cort...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 3(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataEC50:  2.70E+6nMAssay Description:Effective concentration of compound was determined for electrophysiological properties on Ionotropic glutamate receptor AMPA 3 (GluR3) using rat cort...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | cid_119 | Gamma-A...)
Affinity DataEC50:  4.30E+4nMAssay Description:Agonist activity at GABA alpha-1-beta-2-gamma-2 receptor expressed in HEK293 cells by Whole-cell patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50218536(4(5)-(carboxymethyl)-5(4)-methylimidazole | CHEMBL...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at GABA alpha-1-beta-2-gamma-2 receptor expressed in HEK293 cells by Whole-cell patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM85712(1H-imidazol-4-ylacetic acid | NSC_96215 | CAS_645-...)
Affinity DataEC50:  1.38E+5nMAssay Description:Agonist activity at GABA alpha-1-beta-2-gamma-2 receptor expressed in HEK293 cells by Whole-cell patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM10759(2-acetoxyethyl(trimethyl)ammonium;perchlorate | 2-...)
Affinity DataEC50:  1.90E+4nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254538(3-(dimethylamino)butyl methylcarbamate | CHEMBL466...)
Affinity DataEC50:  1.70E+5nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254539(5-(dimethylamino)-N,N-dimethylhexanamide | CHEMBL4...)
Affinity DataEC50:  1.00E+6nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254540(5-(dimethylamino)-N-methylhex-2-enamide | CHEMBL50...)
Affinity DataEC50:  1.58E+5nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254541(5-(dimethylamino)-N,N-dimethylhex-2-enamide | CHEM...)
Affinity DataEC50:  1.00E+5nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254542(O-3-(dimethylamino)butyl dimethylcarbamothioate | ...)
Affinity DataEC50:  5.01E+4nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254597(S-3-(dimethylamino)butyl dimethylcarbamothioate | ...)
Affinity DataEC50:  3.98E+5nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254598(3-(3-(dimethylamino)butyl)-1,1-dimethylurea | CHEM...)
Affinity DataEC50: >3.00E+6nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254599(1-(3-(dimethylamino)butyl)-3-phenylurea | CHEMBL44...)
Affinity DataEC50: >3.00E+6nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254600(3-(dimethylamino)-4-hydroxybutyl dimethylcarbamate...)
Affinity DataEC50: >3.00E+6nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254601(3-cyclopropyl-3-(dimethylamino)propyl dimethylcarb...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254602(3-(dimethylamino)-3-(thiophen-3-yl)propyl dimethyl...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254603(3-(dimethylamino)-3-phenylpropyl dimethylcarbamate...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254604(3-(dimethylamino)butyl 2-hydroxyethyl(methyl)carba...)
Affinity DataEC50:  1.60E+5nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254605(3-(dimethylamino)butyl methyl(phenyl)carbamate | C...)
Affinity DataEC50:  5.10E+4nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254480(3-(dimethylamino)butyl 4-chlorophenyl(methyl)carba...)
Affinity DataEC50:  2.80E+4nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254481(3-(dimethylamino)butyl 4-cyanophenyl(methyl)carbam...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254482(3-(dimethylamino)butyl benzyl(methyl)carbamate | C...)
Affinity DataEC50:  6.70E+3nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254483(3-(dimethylamino)butyl carbamate | CHEMBL449334)
Affinity DataEC50:  5.70E+4nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254484(3-(dimethylamino)butyl ethylcarbamate | CHEMBL4516...)
Affinity DataEC50:  5.01E+4nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254485(3-(dimethylamino)butyl propylcarbamate | CHEMBL466...)
Affinity DataEC50:  9.50E+4nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254486(3-(dimethylamino)butyl 2-hydroxyethylcarbamate | C...)
Affinity DataEC50:  3.00E+5nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254543(3-(dimethylamino)butyl 3-phenylpropylcarbamate | C...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at alpha3beta4 nAChR expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenylate cyclase type 5(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50010714(CHEMBL68922 | 1-p-Tolyl-2,3,4,5-tetrahydro-1H-benz...)
Affinity DataEC50:  210nMAssay Description:Effective concentration required to stimulate Adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetAdenylate cyclase type 5(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004822(CHEMBL24077 | SKF 38393 (+) | SK-383933 | R(+)SKF ...)
Affinity DataEC50:  80nMAssay Description:Effective concentration required to stimulate Adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
University of Lund

Curated by ChEMBL
LigandPNGBDBM50004822(CHEMBL24077 | SKF 38393 (+) | SK-383933 | R(+)SKF ...)
Affinity DataEC50:  71nMAssay Description:Compound was tested for the adenylate cyclase stimulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
University of Lund

Curated by ChEMBL
LigandPNGBDBM50004821(SK-39315A | 2,3,4,5-Tetrahydro-1H-benzo[d]azepine-...)
Affinity DataEC50:  5.20E+3nMAssay Description:Compound was tested for the adenylate cyclase stimulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
University of Lund

Curated by ChEMBL
LigandPNGBDBM50230364(CHEMBL146629)
Affinity DataEC50: >1.00E+4nMAssay Description:Compound was tested for the adenylate cyclase stimulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM10759(2-acetoxyethyl(trimethyl)ammonium;perchlorate | 2-...)
Affinity DataEC50:  4.43E+5nMAssay Description:Effective concentration against Nicotinic acetylcholine receptor alpha3-beta2 expressed in xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataEC50:  1.32E+5nMAssay Description:Effective concentration against Nicotinic acetylcholine receptor alpha3-beta2 expressed in xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-4(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50052593(Altinicline | 3-Ethynyl-5-((S)-1-methyl-pyrrolidin...)
Affinity DataEC50:  3.20E+3nMAssay Description:Effective concentration against Nicotinic acetylcholine receptor alpha2-beta4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50240856(7-Methyl-2-pyridazin-4-yl-7-aza-bicyclo[2.2.1]hept...)
Affinity DataEC50:  2.50E+4nMAssay Description:Effective concentration against Nicotinic acetylcholine receptor alpha 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50052593(Altinicline | 3-Ethynyl-5-((S)-1-methyl-pyrrolidin...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration against Nicotinic acetylcholine receptor alpha 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
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