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Report error Found 1016 with Last Name = 'linden' and Initial = 'j'
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50508823(CHEMBL4544303)
Affinity DataEC50: <1.79E+3nMAssay Description:Induction of HIV1 His/FLAG-tagged integrase hyper-multimerization expressed in Escherichia coli BL21(DE3) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM188497(ALLINI-2 | 2-(6-bromo-4-(4-chlorophenyl)-2-methylq...)
Affinity DataEC50:  146nMAssay Description:Induction of HIV1 His/FLAG-tagged integrase hyper-multimerization expressed in Escherichia coli BL21(DE3) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50451378(CHEMBL39106)
Affinity DataEC50:  0nMAssay Description:AE maximal score at Adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50451379(CHEMBL43299)
Affinity DataEC50:  7.94E+5nMAssay Description:AE maximal score at Adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50451379(CHEMBL43299)
Affinity DataEC50:  6.31E+7nMAssay Description:AE maximal score at Adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50451380(CHEMBL39388)
Affinity DataEC50:  1.58E+7nMAssay Description:AE maximal score at Adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50451378(CHEMBL39106)
Affinity DataEC50:  1.58E+5nMAssay Description:AE maximal score at Adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50451380(CHEMBL39388)
Affinity DataEC50:  1.58E+7nMAssay Description:AE maximal score at Adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50451380(CHEMBL39388)
Affinity DataEC50:  5.01E+8nMAssay Description:AE maximal score at Adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50451379(CHEMBL43299)
Affinity DataEC50:  0.00100nMAssay Description:AE maximal score at Adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50451381(CHEMBL38779)
Affinity DataEC50:  2nMAssay Description:AE maximal score at Adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50114257(7-Cyclopentanecarbonyloxy-8H-indeno[1,2-d]thiazol-...)
Affinity DataEC50:  4.50E+3nMAssay Description:Effective concentration against Adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50114258(5,6,7-Trimethoxy-8H-indeno[1,2-d]thiazol-2-yl-ammo...)
Affinity DataEC50:  1.70E+4nMAssay Description:Effective concentration against Adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50114259(5-Methyl-8H-indeno[1,2-d]thiazol-2-yl-ammonium; io...)
Affinity DataEC50:  4.20E+3nMAssay Description:Effective concentration against Adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50114260(4,5-Dihydro-naphtho[1,2-d]thiazol-2-yl-ammonium; i...)
Affinity DataEC50:  1.70E+4nMAssay Description:Effective concentration against Adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50114261(6-Methoxy-8H-indeno[1,2-d]thiazol-2-yl-ammonium; i...)
Affinity DataEC50:  5.00E+4nMAssay Description:Effective concentration against Adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50114262(8H-Indeno[1,2-d]thiazol-2-yl-ammonium; iodide | CH...)
Affinity DataEC50:  3.80E+4nMAssay Description:Effective concentration against Adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50451381(CHEMBL38779)
Affinity DataEC50:  0nMAssay Description:AE maximal score at Adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50451378(CHEMBL39106)
Affinity DataEC50:  0nMAssay Description:AE maximal score at Adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50080550((2-amino-4,5-dimethylthien-3-yl)-[3-(trifluorometh...)
Affinity DataEC50:  8.40E+3nMAssay Description:Effective dose as dissociation of [3H]N6-cyclohexyladenosine ([3H]CHA) from CHO-K1 membrane after treatment with allosteric enhancer and (R)-PIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50127510([2-amino-5-bromo-4-(3-(trifluoromethyl)phenyl)thio...)
Affinity DataEC50:  6.36E+3nMAssay Description:Effective dose as dissociation of [3H]N6-cyclohexyladenosine ([3H]CHA) from CHO-K1 membrane after treatment with allosteric enhancer and (R)-PIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50253869(5-Amino-3,4-dihydro-4-oxo-3-phenyl-thieno[3,4-d]py...)
Affinity DataEC50:  9.80E+3nMAssay Description:Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50253836(Ethyl 5-amino-4-oxo-3-(4-(trifluoromethylsulfonylo...)
Affinity DataEC50:  4.90E+3nMAssay Description:Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50253835(Ethyl 3-(4-Acetoxyphenyl)-5-amino-4-oxo-3,4-dihydr...)
Affinity DataEC50:  2.50E+3nMAssay Description:Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50253834(Ethyl 5-Amino-3-(4-nitrophenyl)-4-oxo-3,4-dihydrot...)
Affinity DataEC50:  1.30E+4nMAssay Description:Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50253833(Ethyl 5-Amino-4-oxo-3-(4-(trifluoromethyl)phenyl)-...)
Affinity DataEC50:  8.40E+3nMAssay Description:Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50253832(Ethyl 5-amino-3-(4-iodophenyl)-4-oxo-3,4-dihydroth...)
Affinity DataEC50:  7.10E+3nMAssay Description:Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50253797(cid_719449 | CHEMBL460366 | Ethyl 5-Amino-3-(4-met...)
Affinity DataEC50:  4.30E+3nMAssay Description:Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50253796(Ethyl 5-Amino-3-(4-hydroxyphenyl)-4-oxo-3,4-dihydr...)
Affinity DataEC50:  7.10E+3nMAssay Description:Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50253795(Ethyl 5-Amino-4-oxo-3-(3-(trifluoromethyl)phenyl)-...)
Affinity DataEC50:  2.70E+3nMAssay Description:Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50253794(Ethyl 5-amino-3-(3-chlorophenyl)-4-oxo-3,4-dihydro...)
Affinity DataEC50:  5.70E+3nMAssay Description:Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50253793(Ethyl 5-Amino-4-oxo-3-phenyl-3,4-dihydrothieno[3,4...)
Affinity DataEC50:  1.36E+4nMAssay Description:Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50253792(ethyl 5-amino-3-(4-tert-butylphenyl)-4-oxo-3,4-dih...)
Affinity DataEC50:  9.75E+3nMAssay Description:Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50253324(5-amino-3-methyl-N2-phenylthiophene-2,4-dicarboxam...)
Affinity DataEC50:  3.95E+3nMAssay Description:Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50253751((2-amino-4,5-dimethylthiophen-3-yl)(thiophen-2-yl)...)
Affinity DataEC50:  1.12E+4nMAssay Description:Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50253870(5-Amino-3,4-dihydro-3-(4-methoxyphenyl)-4-oxo-thie...)
Affinity DataEC50:  2.60E+3nMAssay Description:Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50080550((2-amino-4,5-dimethylthien-3-yl)-[3-(trifluorometh...)
Affinity DataEC50:  1.36E+4nMAssay Description:Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50304462(2-Amino-N-(3-chlorobenzyl)-6-methyl-4,5,6,7-tetrah...)
Affinity DataEC50:  1.32E+4nMAssay Description:Allosteric modulatory activity at human adenosine A1 receptor expressed in CHOk1 cells assessed as drug level causing half maximal allosteric effect ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50304463(6-tert-Butyl 3-ethyl 2-amino-4,5-dihydrothieno[2,3...)
Affinity DataEC50:  1.32E+4nMAssay Description:Allosteric modulatory activity at human adenosine A1 receptor expressed in CHOk1 cells assessed as drug level causing half maximal allosteric effect ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50304464(2-Amino-N,6-dibenzyl-4,5,6,7-tetrahydrothieno[2,3-...)
Affinity DataEC50:  1.31E+4nMAssay Description:Allosteric modulatory activity at human adenosine A1 receptor expressed in CHOk1 cells assessed as drug level causing half maximal allosteric effect ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50304465(2-Amino-6-(tert-butoxycarbonyl)-4,5,6,7-tetrahydro...)
Affinity DataEC50:  1.21E+4nMAssay Description:Allosteric modulatory activity at human adenosine A1 receptor expressed in CHOk1 cells assessed as drug level causing half maximal allosteric effect ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50304466(2-Amino-N-benzyl-6-methyl-4,5,6,7-tetrahydrothieno...)
Affinity DataEC50:  1.20E+4nMAssay Description:Allosteric modulatory activity at human adenosine A1 receptor expressed in CHOk1 cells assessed as drug level causing half maximal allosteric effect ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50304467(Ethyl 2-amino-4,5,6,7-tetrahydrothieno[2,3-c]pyrid...)
Affinity DataEC50:  1.17E+4nMAssay Description:Allosteric modulatory activity at human adenosine A1 receptor expressed in CHOk1 cells assessed as drug level causing half maximal allosteric effect ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50304468(2-Amino-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]py...)
Affinity DataEC50:  1.16E+4nMAssay Description:Allosteric modulatory activity at human adenosine A1 receptor expressed in CHOk1 cells assessed as drug level causing half maximal allosteric effect ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50304469(2-Amino-6-methyl-N'-phenyl-4,5,6,7-tetrahydrothien...)
Affinity DataEC50:  1.15E+4nMAssay Description:Allosteric modulatory activity at human adenosine A1 receptor expressed in CHOk1 cells assessed as drug level causing half maximal allosteric effect ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50304470(Ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,...)
Affinity DataEC50:  1.03E+4nMAssay Description:Allosteric modulatory activity at human adenosine A1 receptor expressed in CHOk1 cells assessed as drug level causing half maximal allosteric effect ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50304471((R)-Ethyl 2-amino-6-(2-(tert-butoxycarbonyl(methyl...)
Affinity DataEC50:  9.10E+3nMAssay Description:Allosteric modulatory activity at human adenosine A1 receptor expressed in CHOk1 cells assessed as drug level causing half maximal allosteric effect ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50304472(2-Amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]py...)
Affinity DataEC50: >2.00E+4nMAssay Description:Allosteric modulatory activity at human adenosine A1 receptor expressed in CHOk1 cells assessed as drug level causing half maximal allosteric effect ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50304473(2-Amino-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]py...)
Affinity DataEC50: >2.00E+4nMAssay Description:Allosteric modulatory activity at human adenosine A1 receptor expressed in CHOk1 cells assessed as drug level causing half maximal allosteric effect ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50304474(2-Amino-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]py...)
Affinity DataEC50: >2.00E+4nMAssay Description:Allosteric modulatory activity at human adenosine A1 receptor expressed in CHOk1 cells assessed as drug level causing half maximal allosteric effect ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
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