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Found 379 with Last Name = 'liu' and Initial = 'jy'
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100528(CHEMBL3327081)
Affinity DataKi: <0.0200nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100535(CHEMBL3327073)
Affinity DataKi:  0.0200nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100521(CHEMBL3327078 | US10377744, Compound No. 2696)
Affinity DataKi:  0.190nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100519(CHEMBL3327067 | US10377744, Compound No. 2391)
Affinity DataKi:  0.220nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100531(CHEMBL3325465)
Affinity DataKi:  0.230nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100520(CHEMBL3327077 | US10377744, Compound No. 2422 | US...)
Affinity DataKi:  0.310nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100534(CHEMBL3327074)
Affinity DataKi:  0.360nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100541(CHEMBL3327066)
Affinity DataKi:  0.370nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100539(CHEMBL3327069)
Affinity DataKi:  0.430nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100522(CHEMBL3327087)
Affinity DataKi:  0.440nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100542(CHEMBL3327065)
Affinity DataKi:  0.490nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100540(CHEMBL3327068)
Affinity DataKi:  0.490nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50327846(1-(1-(Cyclopropanecarbonyl)piperidin-4-yl)-3-(4-(t...)
Affinity DataKi:  0.550nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100518(CHEMBL3327064 | US10377744, Compound No. 2389)
Affinity DataKi:  0.660nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50327809(1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluorometho...)
Affinity DataKi:  0.910nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100523(CHEMBL3327086)
Affinity DataKi:  0.980nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100532(CHEMBL3327076)
Affinity DataKi:  0.990nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100538(CHEMBL3327070)
Affinity DataKi:  1.20nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100525(CHEMBL3327084)
Affinity DataKi:  1.20nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100537(CHEMBL3327071)
Affinity DataKi:  1.20nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50335967(1-(1-(isopropylsulfonyl)piperidin-4-yl)-3-(4-(trif...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100533(CHEMBL3327075)
Affinity DataKi:  1.20nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100526(CHEMBL3327083)
Affinity DataKi:  1.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100527(CHEMBL3327082)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100524(CHEMBL3327085)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100543(CHEMBL3327063)
Affinity DataKi:  2.20nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100536(CHEMBL3327072)
Affinity DataKi:  2.40nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50327814(1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethy...)
Affinity DataKi:  3nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50335968(1-(1-(methylsulfonyl)piperidin-4-yl)-3-(4-(trifluo...)
Affinity DataKi:  7.20nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100529(CHEMBL3327080)
Affinity DataKi:  11nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50335972(1-(1-acetylpiperidin-4-yl)-3-(4-(trifluoromethyl)p...)
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50100530(CHEMBL3327079)
Affinity DataKi:  111nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50070208(A-65006 | AG-1749 | CHEBI:6375 | Lansoprazole | Pr...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of human FASN enoyl reductase activity using crotonyl CoA as substrate assessed as inhibition of substrate hydrolysis measured every 1 min...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetFatty acid synthase(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50241343((RS)-6-methoxy-2-((4-methoxy-3,5-dimethylpyridin-2...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of purified recombinant FASN TE activity (unknown origin) using 4-MUH as substrate preincubated for 30 mins before substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50241342(5-(difluoromethoxy)-2-((3,4-dimethoxypyridin-2-yl)...)
Affinity DataKi:  4.10E+3nMAssay Description:Inhibition of purified recombinant FASN TE activity (unknown origin) using 4-MUH as substrate preincubated for 30 mins before substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50070208(A-65006 | AG-1749 | CHEBI:6375 | Lansoprazole | Pr...)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibition of purified recombinant FASN TE activity (unknown origin) using 4-MUH as substrate preincubated for 30 mins before substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50070209(Aciphex | CHEBI:8768 | LY-307640 | Rabeprazole)
Affinity DataKi:  5.90E+3nMAssay Description:Inhibition of purified recombinant FASN TE activity (unknown origin) using 4-MUH as substrate preincubated for 30 mins before substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Department of Entomology and University of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM50327850(1-(1-Tosylpiperidin-4-yl)-3-(4-(trifluoromethoxy)p...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Department of Entomology and University of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM50327849(1-(1-(Phenylsulfonyl)piperidin-4-yl)-3-(4-(trifluo...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50327848(1-(1-(Ethylsulfonyl)piperidin-4-yl)-3-(4-(trifluor...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Department of Entomology and University of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM50327847(1-(1-(Trifluoroacetyl)piperidin-4-yl)-3-(4-(triflu...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50327847(1-(1-(Trifluoroacetyl)piperidin-4-yl)-3-(4-(triflu...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Department of Entomology and University of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM50327846(1-(1-(Cyclopropanecarbonyl)piperidin-4-yl)-3-(4-(t...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50327846(1-(1-(Cyclopropanecarbonyl)piperidin-4-yl)-3-(4-(t...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50327845(1-(4-Perfluoroisopropylphenyl)-3-(1-propionylpiper...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50327844(1-(3,5-Dichlorophenyl)-3-(1-propionylpiperidin-4-y...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Department of Entomology and University of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM50327843(1-(4-Phenoxyphenyl)-3-(1-propionylpiperidin-4-yl)u...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Department of Entomology and University of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM50327842(1-Octyl-3-(1-propionylpiperidin-4-yl)urea | CHEMBL...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50327850(1-(1-Tosylpiperidin-4-yl)-3-(4-(trifluoromethoxy)p...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50327851(1-(1-((4-Acetylpiperazin-1-yl)acetyl)piperidin-4-y...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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