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Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36534(D156095)
Affinity DataEC50:  104nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36535(D157554)
Affinity DataEC50:  921nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36536(D153215)
Affinity DataEC50:  243nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM50232538(D156844 | CHEMBL251429 | 5-((1-(2-fluorobenzyl)pip...)
Affinity DataIC50: 7.62nM EC50:  4nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36533(D157555)
Affinity DataIC50: 9.38nM EC50:  108nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36531(D158963)
Affinity DataIC50: 23.4nM EC50:  223nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36530(D157493)
Affinity DataIC50: 43.9nM EC50:  67nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36532(D158885)
Affinity DataIC50: 101nM EC50:  795nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMed
Targetm7GpppX diphosphatase(Human)
Decode Chemistry

LigandPNGBDBM36529(D156676)
Affinity DataIC50: 339nM EC50:  2.54E+3nMAssay Description:In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50369383(CHEMBL1788222)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]prazosin from Alpha-1A adrenergic receptor of rat submaxillary gland membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50066109(3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-2,6-...)
Affinity DataKi:  0.260nMAssay Description:Displacement of [3H]prazosin from Alpha-1A adrenergic receptor of rat submaxillary gland membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50369383(CHEMBL1788222)
Affinity DataKi:  0.420nMAssay Description:Displacement of [3H]prazosin from Alpha-1B adrenergic receptor of rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50040253(3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]prazosin from Alpha-1A adrenergic receptor of rat submaxillary gland membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50040260(2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-2,6-...)
Affinity DataKi:  0.650nMAssay Description:Displacement of [3H]prazosin from Alpha-1A adrenergic receptor of rat submaxillary gland membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50066109(3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-2,6-...)
Affinity DataKi:  0.670nMAssay Description:Displacement of [3H]prazosin from Alpha-1B adrenergic receptor of rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50040253(3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]prazosin from Alpha-1B adrenergic receptor of rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50369382(CHEMBL1788223)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]prazosin from Alpha-1B adrenergic receptor of rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50369382(CHEMBL1788223)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]prazosin from Alpha-1A adrenergic receptor of rat submaxillary gland membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50369382(CHEMBL1788223)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]prazosin from Alpha-1A adrenergic receptor of rat submaxillary gland membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50369382(CHEMBL1788223)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]prazosin from Alpha-1B adrenergic receptor of rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50040260(2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-2,6-...)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]prazosin from Alpha-1B adrenergic receptor of rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50040253(3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  16nMAssay Description:Compound is evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor using [3H]-8-OH- -DPAT in rat brain cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50040253(3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  32nMAssay Description:Compound is evaluated for binding affinity towards Dopamine receptor D2 using [3H]spiperone in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50369382(CHEMBL1788223)
Affinity DataKi: >50nMAssay Description:Compound is evaluated for binding affinity towards Histamine H1 receptor using [3H]pyrilamine in guinea pig lung at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50369382(CHEMBL1788223)
Affinity DataKi: >50nMAssay Description:Compound is evaluated for binding affinity towards recombinant human Dopamine receptor D3 using [3H]spiperone in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50040253(3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi: >50nMAssay Description:Compound is evaluated for binding affinity towards Sigma receptor using [3H]pentazocine in guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50455098(CHEMBL2092926)
Affinity DataKi:  55nMAssay Description:Displacement of [3H]prazosin from Alpha-1A adrenergic receptor of rat submaxillary gland membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAlpha-2B adrenergic receptor(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50040253(3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  56nMAssay Description:Compound is evaluated for binding affinity towards Alpha-2B adrenergic receptor using [3H]prazosinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50040253(3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  73nMAssay Description:Compound is evaluated for binding affinity towards recombinant human Dopamine receptor D3 using [3H]spiperone in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAlpha-2B adrenergic receptor(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50369383(CHEMBL1788222)
Affinity DataKi:  116nMAssay Description:Compound is evaluated for binding affinity towards Alpha-2B adrenergic receptor using [3H]prazosinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50455096(CHEMBL2092927)
Affinity DataKi:  122nMAssay Description:Displacement of [3H]prazosin from Alpha-1A adrenergic receptor of rat submaxillary gland membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50455098(CHEMBL2092926)
Affinity DataKi:  123nMAssay Description:Displacement of [3H]prazosin from Alpha-1B adrenergic receptor of rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50040253(3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  132nMAssay Description:Compound is evaluated for binding affinity towards recombinant human Dopamine receptor D2 using [3H]spiperone in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50066109(3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-2,6-...)
Affinity DataKi:  155nMAssay Description:Compound is evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor using [3H]-8-OH- -DPAT in rat brain cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50369382(CHEMBL1788223)
Affinity DataKi:  237nMAssay Description:Compound is evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor using [3H]-8-OH- -DPAT in rat brain cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50040260(2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-2,6-...)
Affinity DataKi:  238nMAssay Description:Compound is evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor using [3H]-8-OH- -DPAT in rat brain cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50066109(3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-2,6-...)
Affinity DataKi:  239nMAssay Description:Compound is evaluated for binding affinity towards recombinant human Dopamine receptor D2 using [3H]spiperone in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50066109(3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-2,6-...)
Affinity DataKi:  239nMAssay Description:Compound is evaluated for binding affinity towards recombinant human Dopamine receptor D2 using [3H]spiperone in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAlpha-2B adrenergic receptor(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50040260(2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-2,6-...)
Affinity DataKi:  253nMAssay Description:Compound is evaluated for binding affinity towards Alpha-2B adrenergic receptor using [3H]prazosinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAlpha-2B adrenergic receptor(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50369382(CHEMBL1788223)
Affinity DataKi:  376nMAssay Description:Compound is evaluated for binding affinity towards Alpha-2B adrenergic receptor using [3H]prazosinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50369383(CHEMBL1788222)
Affinity DataKi:  444nMAssay Description:Compound is evaluated for binding affinity towards Alpha-2A adrenergic receptor using [3H]prazosinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50369382(CHEMBL1788223)
Affinity DataKi:  449nMAssay Description:Compound is evaluated for binding affinity towards Dopamine receptor D2 using [3H]spiperone in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50369382(CHEMBL1788223)
Affinity DataKi:  449nMAssay Description:Compound is evaluated for binding affinity towards Dopamine receptor D2 using [3H]spiperone in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50369382(CHEMBL1788223)
Affinity DataKi:  451nMAssay Description:Compound is evaluated for binding affinity towards Sigma receptor using [3H]pentazocine in guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50040260(2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-2,6-...)
Affinity DataKi:  547nMAssay Description:Compound is evaluated for binding affinity towards Alpha-2A adrenergic receptor using [3H]prazosinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50455096(CHEMBL2092927)
Affinity DataKi:  667nMAssay Description:Displacement of [3H]prazosin from Alpha-1B adrenergic receptor of rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50040253(3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  685nMAssay Description:Compound is evaluated for binding affinity towards Histamine H1 receptor using [3H]pyrilamine in guinea pig lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50066110(2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-6H-i...)
Affinity DataKi:  743nMAssay Description:Compound is evaluated for binding affinity towards Sigma receptor using [3H]pentazocine in guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50369382(CHEMBL1788223)
Affinity DataKi:  872nMAssay Description:Compound is evaluated for binding affinity towards Alpha-2A adrenergic receptor using [3H]prazosinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50040260(2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-2,6-...)
Affinity DataKi:  961nMAssay Description:Compound is evaluated for binding affinity towards Histamine H1 receptor using [3H]pyrilamine in guinea pig lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
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