Compile Data Set for Download or QSAR
Found 12880 with Last Name = 'lockhart' and Initial = 'dj'
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human cdc2/cyclin B assessed as [32P] incorporation in histone H1 from [gamma32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human cdk5/p35More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human cdk2/cyclin AMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human cdc2/cyclin B assessed as [32P] incorporation in histone H1 from [gamma32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human cdk2/cyclin EMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human cdk2/cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCdc2(Asterina pectinifera)
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50:  40nMAssay Description:Inhibition of starfish cdc2/cyclin B assessed as [32P] incorporation in histone H1 from 150 M [gamma32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCdc2(Asterina pectinifera)
University of California

Curated by ChEMBL
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50:  50nMAssay Description:Inhibition of starfish cdc2/cyclin B assessed as [32P] incorporation in histone H1 from 150 M [gamma32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human cdk2/cyclin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50:  75nMAssay Description:Inhibition of human cdk5/p35More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Saccharomyces cerevisiae)
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50:  80nMAssay Description:Inhibition of Saccharomyces cerevisiae cdc28More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCdc2(Asterina pectinifera)
University of California

Curated by ChEMBL
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50:  250nMAssay Description:Inhibition of starfish cdc2/cyclin B assessed as [32P] incorporation in histone H1 from 1.5 mM [gamma32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50113707(2,6,9-Trisubstitute purine, 2 | 2-(2-hydroxyethyla...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human cdc2/cyclin B assessed as [32P] incorporation in histone H1 from [gamma32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCdc2(Asterina pectinifera)
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50:  500nMAssay Description:Inhibition of starfish cdc2/cyclin B assessed as [32P] incorporation in histone H1 from 1.5 mM [gamma32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50:  850nMAssay Description:Inhibition of human cdk4/cyclin D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Saccharomyces cerevisiae)
University of California

Curated by ChEMBL
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of Saccharomyces cerevisiae cdc28More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent protein kinase PHO85(Saccharomyces cerevisiae)
University of California

Curated by ChEMBL
LigandPNGBDBM50113707(2,6,9-Trisubstitute purine, 2 | 2-(2-hydroxyethyla...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of yeast W303 Pho85 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human insulin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50:  3.33E+3nMAssay Description:Inhibition of human Erk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human insulin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Saccharomyces cerevisiae)
University of California

Curated by ChEMBL
LigandPNGBDBM50113707(2,6,9-Trisubstitute purine, 2 | 2-(2-hydroxyethyla...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of yeast W303 cdc28 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human Erk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human cdk4/cyclin D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C gamma type(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PKCgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PKCbeta1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PKCbeta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PKCbeta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PKCzetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PKCepsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PKCdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C gamma type(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PKCgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PKCbeta1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C eta type(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PKCetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PKCdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PKCepsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PKCzetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C eta type(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PKCetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent protein kinase PHO85(Saccharomyces cerevisiae)
University of California

Curated by ChEMBL
LigandPNGBDBM50267719(2-(6-((3-chlorophenyl)(methyl)amino)-9-isopropyl-9...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of yeast W303 Pho85 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMeiotic mRNA stability protein kinase SSN3(Saccharomyces cerevisiae)
University of California

Curated by ChEMBL
LigandPNGBDBM50113707(2,6,9-Trisubstitute purine, 2 | 2-(2-hydroxyethyla...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of yeast W303 Srb10 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase KIN28(Saccharomyces cerevisiae)
University of California

Curated by ChEMBL
LigandPNGBDBM50267719(2-(6-((3-chlorophenyl)(methyl)amino)-9-isopropyl-9...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of yeast W303 Kin28 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase CAK1(Saccharomyces cerevisiae)
University of California

Curated by ChEMBL
LigandPNGBDBM50113707(2,6,9-Trisubstitute purine, 2 | 2-(2-hydroxyethyla...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of yeast W303 Cak1 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMeiotic mRNA stability protein kinase SSN3(Saccharomyces cerevisiae)
University of California

Curated by ChEMBL
LigandPNGBDBM50267719(2-(6-((3-chlorophenyl)(methyl)amino)-9-isopropyl-9...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of yeast W303 Srb10 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Saccharomyces cerevisiae)
University of California

Curated by ChEMBL
LigandPNGBDBM50267719(2-(6-((3-chlorophenyl)(methyl)amino)-9-isopropyl-9...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of yeast W303 cdc28 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase CAK1(Saccharomyces cerevisiae)
University of California

Curated by ChEMBL
LigandPNGBDBM50267719(2-(6-((3-chlorophenyl)(methyl)amino)-9-isopropyl-9...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of yeast W303 Cak1 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase KIN28(Saccharomyces cerevisiae)
University of California

Curated by ChEMBL
LigandPNGBDBM50113707(2,6,9-Trisubstitute purine, 2 | 2-(2-hydroxyethyla...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of yeast W303 Kin28 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1 [201-500](Homo sapiens (Human))
Ambit, Inc.

LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataKd:  2nMpH: 7.4 T: 2°CAssay Description:Competition binding assay was used to measure the interaction between the phage-tagged kinase, immobilized competitive ligand, and unlinked test comp...More data for this Ligand-Target Pair
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