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TargetReplicase polyprotein 1ab(BtCoV)
Pfizer

WIPO
LigandPNGBDBM420298(CVD-0006356 | PF-00835231 | PF-0835231 | US1152494...)
Affinity DataKi:  0.0300nMAssay Description:Proteolytic activity of SARS-CoV-2 Coronavirus 3CL protease is measured using a continuous fluorescence resonance energy transfer assay. The SARS-CoV...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(BtCoV)
Pfizer

WIPO
LigandPNGBDBM420298(CVD-0006356 | PF-00835231 | PF-0835231 | US1152494...)
Affinity DataKi:  0.0300nMAssay Description:Proteolytic activity of SARS-CoV-2 Coronavirus 3CL protease is measured using a continuous fluorescence resonance energy transfer assay. The SARS-CoV...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(BtCoV)
Pfizer

WIPO
LigandPNGBDBM420298(CVD-0006356 | PF-00835231 | PF-0835231 | US1152494...)
Affinity DataKi:  0.0330nMAssay Description:PF-00835231 was evaluated against 3CLpro from a variety of other coronaviruses representing alpha, beta and gamma groups of Coronaviridae, using bioc...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(BtCoV)
Pfizer

WIPO
LigandPNGBDBM420298(CVD-0006356 | PF-00835231 | PF-0835231 | US1152494...)
Affinity DataKi:  0.0340nMAssay Description:PF-00835231 was evaluated against 3CLpro from a variety of other coronaviruses representing alpha, beta and gamma groups of Coronaviridae, using bioc...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Feline coronavirus (strain FIPV WSU-79/1146) (FCoV...)
Pfizer

WIPO
LigandPNGBDBM420298(CVD-0006356 | PF-00835231 | PF-0835231 | US1152494...)
Affinity DataKi:  0.100nMAssay Description:Proteolytic activity of SARS-CoV-2 Coronavirus 3CL protease is measured using a continuous fluorescence resonance energy transfer assay. The SARS-CoV...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(Feline coronavirus (strain FIPV WSU-79/1146) (FCoV...)
Pfizer

WIPO
LigandPNGBDBM420298(CVD-0006356 | PF-00835231 | PF-0835231 | US1152494...)
Affinity DataKi:  0.120nMAssay Description:PF-00835231 was evaluated against 3CLpro from a variety of other coronaviruses representing alpha, beta and gamma groups of Coronaviridae, using bioc...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM50491017(CHEMBL2377343)
Affinity DataKi:  0.190nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM50363527(CHEMBL1945412 | US9481685, [18F]FE-PBR)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM50491024(CHEMBL2377352)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM50491021(CHEMBL2377344)
Affinity DataKi:  0.260nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

LigandPNGBDBM420298(CVD-0006356 | PF-00835231 | PF-0835231 | US1152494...)
Affinity DataKi:  0.270nMAssay Description:PF-00835231 was evaluated against 3CLpro from a variety of other coronaviruses representing alpha, beta and gamma groups of Coronaviridae, using bioc...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM253019(US9481685, 1)
Affinity DataKi:  0.290nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM50490999(CHEMBL2377340)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(PEDV)
Pfizer

LigandPNGBDBM420298(CVD-0006356 | PF-00835231 | PF-0835231 | US1152494...)
Affinity DataKi:  0.300nMAssay Description:PF-00835231 was evaluated against 3CLpro from a variety of other coronaviruses representing alpha, beta and gamma groups of Coronaviridae, using bioc...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(PEDV)
Pfizer

LigandPNGBDBM420298(CVD-0006356 | PF-00835231 | PF-0835231 | US1152494...)
Affinity DataKi:  0.300nMAssay Description:Proteolytic activity of SARS-CoV-2 Coronavirus 3CL protease is measured using a continuous fluorescence resonance energy transfer assay. The SARS-CoV...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails PubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM50490998(CHEMBL2377339)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM253021(US9481685, 4)
Affinity DataKi:  0.310nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM253022(US9481685, 5)
Affinity DataKi:  0.320nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM50491013(CHEMBL2377338)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM50491007(CHEMBL2377334)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM50491000(CHEMBL2377345)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM50491004(CHEMBL2377357)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM50491022(CHEMBL2377360)
Affinity DataKi:  0.360nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM50490997(CHEMBL2377337)
Affinity DataKi:  0.390nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM50491016(CHEMBL2377332)
Affinity DataKi:  0.390nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM253024(US9481685, 2)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM50491006(CHEMBL2377346)
Affinity DataKi:  0.470nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM50491014(CHEMBL2377347)
Affinity DataKi:  0.490nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(HCoV-OC43)
Pfizer

WIPO
LigandPNGBDBM420298(CVD-0006356 | PF-00835231 | PF-0835231 | US1152494...)
Affinity DataKi:  0.5nMAssay Description:Proteolytic activity of SARS-CoV-2 Coronavirus 3CL protease is measured using a continuous fluorescence resonance energy transfer assay. The SARS-CoV...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(HCoV-OC43)
Pfizer

WIPO
LigandPNGBDBM420298(CVD-0006356 | PF-00835231 | PF-0835231 | US1152494...)
Affinity DataKi:  0.510nMAssay Description:PF-00835231 was evaluated against 3CLpro from a variety of other coronaviruses representing alpha, beta and gamma groups of Coronaviridae, using bioc...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM50491015(CHEMBL2377359)
Affinity DataKi:  0.520nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM253023(US9481685, 6)
Affinity DataKi:  0.520nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM50491012(CHEMBL2377333)
Affinity DataKi:  0.550nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(BtCoV)
Pfizer

LigandPNGBDBM420298(CVD-0006356 | PF-00835231 | PF-0835231 | US1152494...)
Affinity DataKi:  0.740nMAssay Description:PF-00835231 was evaluated against 3CLpro from a variety of other coronaviruses representing alpha, beta and gamma groups of Coronaviridae, using bioc...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM50491003(CHEMBL2377355)
Affinity DataKi:  0.760nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(HCoV-NL63)
Pfizer

LigandPNGBDBM420298(CVD-0006356 | PF-00835231 | PF-0835231 | US1152494...)
Affinity DataKi:  0.770nMAssay Description:PF-00835231 was evaluated against 3CLpro from a variety of other coronaviruses representing alpha, beta and gamma groups of Coronaviridae, using bioc...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM50490994(CHEMBL2377327)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(BtCoV)
Pfizer

LigandPNGBDBM420298(CVD-0006356 | PF-00835231 | PF-0835231 | US1152494...)
Affinity DataKi:  0.800nMAssay Description:Proteolytic activity of SARS-CoV-2 Coronavirus 3CL protease is measured using a continuous fluorescence resonance energy transfer assay. The SARS-CoV...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(HCoV-NL63)
Pfizer

LigandPNGBDBM420298(CVD-0006356 | PF-00835231 | PF-0835231 | US1152494...)
Affinity DataKi:  0.800nMAssay Description:Proteolytic activity of SARS-CoV-2 Coronavirus 3CL protease is measured using a continuous fluorescence resonance energy transfer assay. The SARS-CoV...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(HCoV-HKU1)
Pfizer

LigandPNGBDBM420298(CVD-0006356 | PF-00835231 | PF-0835231 | US1152494...)
Affinity DataKi:  0.850nMAssay Description:PF-00835231 was evaluated against 3CLpro from a variety of other coronaviruses representing alpha, beta and gamma groups of Coronaviridae, using bioc...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(HCoV-HKU1)
Pfizer

LigandPNGBDBM420298(CVD-0006356 | PF-00835231 | PF-0835231 | US1152494...)
Affinity DataKi:  0.900nMAssay Description:Proteolytic activity of SARS-CoV-2 Coronavirus 3CL protease is measured using a continuous fluorescence resonance energy transfer assay. The SARS-CoV...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails PubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM253020(US9481685, 3)
Affinity DataKi:  0.930nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM253018(US9481685, 7)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM50491008(CHEMBL2377342)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM50491020(CHEMBL2377328)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM253019(US9481685, 1)
Affinity DataKi:  1.17nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM253019(US9481685, 1)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(MHV-A59)
Pfizer

LigandPNGBDBM420298(CVD-0006356 | PF-00835231 | PF-0835231 | US1152494...)
Affinity DataKi:  1.20nMAssay Description:PF-00835231 was evaluated against 3CLpro from a variety of other coronaviruses representing alpha, beta and gamma groups of Coronaviridae, using bioc...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(MHV-A59)
Pfizer

LigandPNGBDBM420298(CVD-0006356 | PF-00835231 | PF-0835231 | US1152494...)
Affinity DataKi:  1.20nMAssay Description:Proteolytic activity of SARS-CoV-2 Coronavirus 3CL protease is measured using a continuous fluorescence resonance energy transfer assay. The SARS-CoV...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails PubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Ge Healthcare

Curated by ChEMBL
LigandPNGBDBM50490996(CHEMBL2377331)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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