Report error Found 966 with Last Name = 'lynch' and Initial = 'kr'
Affinity DataKi: 0.0900nMAssay Description:Inhibition of recombinant human Sphk2 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m...More data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Inhibition of recombinant human Sphk2 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m...More data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Inhibition of recombinant human Sphk2 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of recombinant human Sphk2 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m...More data for this Ligand-Target Pair
Affinity DataKi: 0.980nMAssay Description:Inhibition of recombinant human Sphk2 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of recombinant human Sphk2 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m...More data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Inhibition of recombinant human SphK1 expressed in baculovirus infected Sf9 cells assessed as decrease in [33P]SIP production using D-erythro-sphingo...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 3.60nMAssay Description:Inhibition of SphK1 in mouse erythrocytes using sphingosine as substrate by luminescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Inhibition of recombinant human C-terminal His-tagged SPHK1 expressed in fall armyworm sf21 cells using sphingosine as substrate after 1 hr by FITC-b...More data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Competitive-inhibition of recombinant human C-terminal His6-tagged Sphk1 expressed in baculovirus infected Sf21 insect cells using varying levels of ...More data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Inhibition of human recombinant SphK1 expressed in Sf9 cells assessed as radiolabeled products using 5 uM sphingosine and 10 uM gamma[32P]ATP by liqu...More data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:Inhibition of recombinant human Sphk1 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of recombinant human Sphk1 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m...More data for this Ligand-Target Pair
Affinity DataKi: >10nMAssay Description:Inhibition of recombinant human Sphk1 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m...More data for this Ligand-Target Pair
Affinity DataKi: >10nMAssay Description:Inhibition of recombinant human Sphk1 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m...More data for this Ligand-Target Pair
Affinity DataKi: >10nMAssay Description:Inhibition of recombinant human Sphk1 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Antagonist activity at LPAR1/LPAR3 in rat glioma C62B cells assessed as inhibition of LPA-induced reduction in isoproterenol-stimulated [3H]cAMP accu...More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Binding affinity towards Lysophosphatidic acid 1 (LPA1) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:In vitro ability to antagonize LPA-evoked [35S]-GTP-gammaS binding to lysophosphatidic acid receptor 1 in HEK293T cell linesMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Binding affinity towards Lysophosphatidic acid 1 (LPA1) receptorMore data for this Ligand-Target Pair
Affinity DataKi: >20nMAssay Description:Inhibition of recombinant human Sphk1 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m...More data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Binding affinity towards Lysophosphatidic acid 1 (LPA1) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Binding affinity towards Lysophosphatidic acid 1 (LPA1) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of [32P]S1P from human S1P1 receptor expressed in HEK293T cellsMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of [32P]S1P from human S1P1 receptor expressed in HEK293T cellsMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Human)
The Centre For Addiction and Mental Health
Curated by PDSP Ki Database
The Centre For Addiction and Mental Health
Curated by PDSP Ki Database
Affinity DataKi: 34nMAssay Description:In vitro ability to antagonize LPA-evoked [35S]-GTP-gammaS binding to lysophosphatidic acid receptor 1 in HEK293T cell linesMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Binding affinity towards Lysophosphatidic acid 1 (LPA1) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Binding affinity towards Lysophosphatidic acid 3 (LPA3) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Binding affinity towards Lysophosphatidic acid 3 (LPA3) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Inhibition of human SphK1 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Binding affinity towards Lysophosphatidic acid 3 (LPA3) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Inhibition of recombinant human SphK1 expressed in baculovirus infected Sf9 cells assessed as decrease in [33P]SIP production using D-erythro-sphingo...More data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Inhibition of human recombinant SphK1 expressed in Sf9 cells assessed as radiolabeled products using 5 uM sphingosine and 10 uM gamma[32P]ATP by liqu...More data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Competitive antagonist activity at N-terminal 3XHA-tagged human LPA3 receptor overexpressed in CHO cells assessed as inhibition of LPA-induced [35S]G...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Human)
The Centre For Addiction and Mental Health
Curated by PDSP Ki Database
The Centre For Addiction and Mental Health
Curated by PDSP Ki Database
Affinity DataKi: 64nMAssay Description:Binding affinity towards Lysophosphatidic acid 1 (LPA1) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Inhibition of human SphK1 expressed in baculovirus infected in Sf9 cells using D-erythro-sphingosine as substrate and [gamma-32P]ATP by scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 73nMAssay Description:In vitro ability to antagonize LPA-evoked [35S]-GTP-gammaS binding to lysophosphatidic acid receptor 1 in HEK293T cell linesMore data for this Ligand-Target Pair
Affinity DataKi: 75nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 75nM ΔG°: -42.3kJ/moleT: 37°CAssay Description:Sphingosine kinase activity was assessed as described previously (Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'Neill, S. L., Morris, M. A., Set...More data for this Ligand-Target Pair
Affinity DataKi: 84nMAssay Description:Competitive antagonist activity at human LPA1 receptor overexpressed in CHO cells assessed as inhibition of LPA-induced [35S]GTPgammaS binding by liq...More data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:Inhibition of recombinant human SphK2 expressed in baculovirus infected Sf9 cells assessed as decrease in [33P]S1P production using varying level of ...More data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:Inhibition of recombinant human SphK2 assessed as decrease in [33P]SIP production using sphingosine as substrate in presence of [gamma33P]-ATP by sci...More data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Inhibition of recombinant human SPHK2 at using sphingosine as substrate after 30 mins in presence of gamma-[32P]-ATP by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Inhibition of recombinant human SPHK2 at using sphingosine as substrate after 30 mins in presence of gamma-[32P]-ATP by liquid scintillation countingMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
University of Virginia
Curated by ChEMBL
University of Virginia
Curated by ChEMBL
Affinity DataKi: 94nMAssay Description:Inhibition of autotoxin assessed as choline release from LPC using lysophosphatidylcholine as substrateMore data for this Ligand-Target Pair
