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TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  0.0558nMAssay Description:Displacement of [3H]epibatidine from human recombinant alpha4beta2 nAChR in HEK293 cells by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50194072(syn-7-(6-chloro-pyridin-3-yl)-2-azabicyclo[2.2.1]h...)
Affinity DataKi:  0.0785nMAssay Description:Displacement of [3H]epibatidine from human recombinant alpha4beta2 nAChR in HEK293 cells by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50194070(CHEMBL94427 | 6-(6-Chloro-pyridin-3-yl)-8-aza-bicy...)
Affinity DataKi:  0.343nMAssay Description:Displacement of [3H]epibatidine from human recombinant alpha4beta2 nAChR in HEK293 cells by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50194070(CHEMBL94427 | 6-(6-Chloro-pyridin-3-yl)-8-aza-bicy...)
Affinity DataKi:  0.343nMAssay Description:Displacement of [3H]epibatidine from human recombinant alpha4beta2 nAChR in HEK293 cells by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50194068(7-(3-methylisoxazol-5-yl)-6-aza-bicyclo[2.2.1]hept...)
Affinity DataKi:  0.763nMAssay Description:Displacement of [3H]epibatidine from human recombinant alpha4beta2 nAChR in HEK293 cells by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50194069(6-(6-Chloro-pyridin-3-yl)-2-aza-bicyclo[2.2.1]hept...)
Affinity DataKi:  0.771nMAssay Description:Displacement of [3H]epibatidine from human recombinant alpha4beta2 nAChR in HEK293 cells by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50194071(3-(6-chloropyridin-3-yl)-6-aza-bicyclo[2.2.1]hepta...)
Affinity DataKi:  1.23nMAssay Description:Displacement of [3H]epibatidine from human recombinant alpha4beta2 nAChR in HEK293 cells by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50194071(3-(6-chloropyridin-3-yl)-6-aza-bicyclo[2.2.1]hepta...)
Affinity DataKi:  1.23nMAssay Description:Displacement of [3H]epibatidine from human recombinant alpha4beta2 nAChR in HEK293 cells by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50143282((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...)
Affinity DataKi:  2.59nMAssay Description:Displacement of [3H]epibatidine from human recombinant alpha4beta2 nAChR in HEK293 cells by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50143320(2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]hept...)
Affinity DataKi:  4.90nMAssay Description:Displacement of [125I-alpha]-Bungarotoxin from alpha-7 nAChR in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50194074(3-(6-chloropyridin-3-yl)-6-aza-bicyclo[2.2.1]hepta...)
Affinity DataKi:  6.30nMAssay Description:Displacement of [125I-alpha]-Bungarotoxin from alpha-7 nAChR in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50143314(CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...)
Affinity DataKi:  7nMAssay Description:Displacement of [125I-alpha]-Bungarotoxin from alpha-7 nAChR in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50194073(homoepibatidine | CHEMBL535389)
Affinity DataKi:  13nMAssay Description:Displacement of [125I-alpha]-Bungarotoxin from alpha-7 nAChR in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50194069(6-(6-Chloro-pyridin-3-yl)-2-aza-bicyclo[2.2.1]hept...)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [125I-alpha]-Bungarotoxin from alpha-7 nAChR in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50194069(6-(6-Chloro-pyridin-3-yl)-2-aza-bicyclo[2.2.1]hept...)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [125I-alpha]-Bungarotoxin from alpha-7 nAChR in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50194071(3-(6-chloropyridin-3-yl)-6-aza-bicyclo[2.2.1]hepta...)
Affinity DataKi:  3.30E+3nMAssay Description:Displacement of [125I-alpha]-Bungarotoxin from alpha-7 nAChR in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed