Compile Data Set for Download or QSAR
Report error Found 19 with Last Name = 'mapelli' and Initial = 'm'
TargetCyclin-dependent kinase 5 activator 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50132003((Z)-1H,1''H-[2,3'']Biindolylidene-3,2''-dione 3-ox...)
Affinity DataIC50: 100nMAssay Description:Inhibition of cyclin-dependent kinase 5/p25More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM7377(CHEMBL75680 | aloisine A | 7-n-Butyl-6-(4-hydroxyp...)
Affinity DataIC50: 200nMAssay Description:Inhibition of cyclin-dependent kinase 5/p25; range 0.16-0.2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 200nMAssay Description:Inhibition of cyclin-dependent kinase 5/p25; range 0.1-0.2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Harvard Medical School

LigandPNGBDBM59195(4-aminothiazole, 2.1)
Affinity DataIC50: 700nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Harvard Medical School

LigandPNGBDBM50155420(Xanthen-9-one, 1.1 | 1,5,8-Trihydroxy-3-methoxy-xa...)
Affinity DataIC50: 700nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Harvard Medical School

LigandPNGBDBM59201(2,3-dihydro-1H-4-oxa-2,5-diazaphenanthrenes, 3.2)
Affinity DataIC50: 2.30E+3nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Harvard Medical School

LigandPNGBDBM59200(2,3-dihydro-1H-4-oxa-2,5-diazaphenanthrenes, 3.1)
Affinity DataIC50: 6.70E+3nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Harvard Medical School

LigandPNGBDBM59199(2,3-dihydro-1H-4-oxa-2,5-diazaphenanthrenes, 3.0)
Affinity DataIC50: 1.70E+4nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Harvard Medical School

LigandPNGBDBM50155436(Xanthen-9-one, 1.4 | CHEMBL365234 | 1,3,5-Trihydro...)
Affinity DataIC50: 2.60E+4nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Harvard Medical School

LigandPNGBDBM59196(4-aminothiazole, 2.2)
Affinity DataIC50: 3.80E+4nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Harvard Medical School

LigandPNGBDBM59197(4-aminothiazole, 2.3)
Affinity DataIC50: 6.60E+4nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Harvard Medical School

LigandPNGBDBM59198(4-aminothiazole, 2.4)
Affinity DataIC50: 1.00E+5nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Harvard Medical School

LigandPNGBDBM59192(Xanthen-9-one, 1.3)
Affinity DataIC50: 2.47E+5nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Harvard Medical School

LigandPNGBDBM59191(Xanthen-9-one, 1.2)
Affinity DataIC50: 5.33E+5nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Harvard Medical School

LigandPNGBDBM59193(Xanthen-9-one, 1.5)
Affinity DataIC50: 1.00E+6nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Harvard Medical School

LigandPNGBDBM50155426(Xanthen-9-one, 1.0 | 1,3,5,8-Tetrahydroxy-xanthen-...)
Affinity DataKi:  140nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Harvard Medical School

LigandPNGBDBM50155426(Xanthen-9-one, 1.0 | 1,3,5,8-Tetrahydroxy-xanthen-...)
Affinity DataKi:  200nM IC50: 200nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Harvard Medical School

LigandPNGBDBM59194(4-aminothiazole, 2.0)
Affinity DataKi:  660nM IC50: 2.00E+3nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 5(Human)
Harvard Medical School

LigandPNGBDBM59194(4-aminothiazole, 2.0)
Affinity DataKi:  690nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)