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TargetAdenosine deaminase(Bovine)
Universita Di Pisa

LigandPNGBDBM28377(2-nonyl-2H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one | ...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The activity of ADA was determined spectrophotometrically by monitoring the change in absorbance at 262 nm, due to the deamination of adenosine catal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
TargetAdenosine deaminase(Bovine)
Universita Di Pisa

LigandPNGBDBM28378(2-decyl-2H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one | ...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The activity of ADA was determined spectrophotometrically by monitoring the change in absorbance at 262 nm, due to the deamination of adenosine catal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
TargetAdenosine deaminase(Bovine)
Universita Di Pisa

LigandPNGBDBM28379(2-undecyl-2H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one ...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The activity of ADA was determined spectrophotometrically by monitoring the change in absorbance at 262 nm, due to the deamination of adenosine catal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50316600(N,N-Dipropyl-[5-isothiocyanato-2-phenylindol-3-yl)...)
Affinity DataKd:  3.17nMAssay Description:Irreversible binding affinity to TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50316601(N,N-Dihexyl-[5-isothiocyanato-2-phenylindol-3-yl)g...)
Affinity DataKd:  5.07nMAssay Description:Irreversible binding affinity to TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50316602(N-(5-Isothiocyanato-2-phenylindol-3-ylglyoxyl)-N'-...)
Affinity DataKd:  8.31nMAssay Description:Irreversible binding affinity to TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50175548(N-Hydroxy-2-(4-phenoxy-benzenesulfonylamino)-aceta...)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of human recombinant MMP2 using Mca-Lys-Pro- Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50318267(4-methoxy-N-(2-methyl-6-phenyl-2H-pyrazolo[3,4-d]p...)
Affinity DataIC50: 0.0610nMAssay Description:Antagonist activity at adenosine A3 receptor in human U87MG cells assessed as inhibition of Cl-IB-MECA-mediated ERK1/2 phosphorylation after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM3032(CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...)
Affinity DataIC50: 0.0950nMAssay Description:Inhibition of recombinant human EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate measured after 15 mins by LANCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50175548(N-Hydroxy-2-(4-phenoxy-benzenesulfonylamino)-aceta...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human recombinant MMP13 using Mca-Lys-Pro- Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50429816(CHEMBL2337697)
Affinity DataIC50: 0.430nMAssay Description:Inhibition of human recombinant MMP2 using Mca-Lys-Pro- Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50224352(4-methoxy-N-(1-oxo-2-p-tolyl-1H-3,3,5,9b-tetraaza-...)
Affinity DataIC50: 0.580nMAssay Description:Antagonist activity at human adenosine A3 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50429816(CHEMBL2337697)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of human recombinant MMP13 using Mca-Lys-Pro- Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50318268(N-(2-methyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4...)
Affinity DataIC50: 0.740nMAssay Description:Antagonist activity at adenosine A3 receptor in human U87MG cells assessed as inhibition of Cl-IB-MECA-mediated ERK1/2 phosphorylation after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50083922(CHEMBL7113 | 3-Phenyl-10H-benzo[4,5]imidazo[2,1-c]...)
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at human A2B receptor expressed in CHO cells assessed as inhibition of NECA-mediated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50429819(CHEMBL2337690)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant MMP2 using Mca-Lys-Pro- Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50429819(CHEMBL2337690)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant MMP13 using Mca-Lys-Pro- Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50318268(N-(2-methyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4...)
Affinity DataIC50: 1.90nMAssay Description:Antagonist activity human recombinant adenosine A3 receptor expressed in CHO cells assessed as blockade of NECA-mediated inhibition of forskolin-stim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50383006(CHEMBL2030704)
Affinity DataIC50: 2.11nMAssay Description:Antagonist activity at human A2B receptor expressed in CHO cells assessed as inhibition of NECA-mediated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50318267(4-methoxy-N-(2-methyl-6-phenyl-2H-pyrazolo[3,4-d]p...)
Affinity DataIC50: 2.40nMAssay Description:Antagonist activity human recombinant adenosine A3 receptor expressed in CHO cells assessed as blockade of NECA-mediated inhibition of forskolin-stim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50383007(CHEMBL2030703)
Affinity DataIC50: 2.42nMAssay Description:Antagonist activity at human A2B receptor expressed in CHO cells assessed as inhibition of NECA-mediated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50383005(CHEMBL2030705)
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at human A2B receptor expressed in CHO cells assessed as inhibition of NECA-mediated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50104963(2-(Cyclopropylmethyl-amino)-N*1*-hydroxy-3-(3-hydr...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant ADAMTS4 expressed in HEk293 cells using FAM-AEwLQGRPISIAK-TAMRA as substrate measured for 15 mins by fluorometric ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50383004(CHEMBL2030707)
Affinity DataIC50: 3.10nMAssay Description:Antagonist activity at human A2B receptor expressed in CHO cells assessed as inhibition of NECA-mediated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50224355(N-(8-chloro-1-oxo-2-phenyl-1H-3,3a,5,9b-tetraaza-c...)
Affinity DataIC50: 3.14nMAssay Description:Antagonist activity at human adenosine A3 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human recombinant MMP1 using Mca-Lys-Pro- Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50175535(2-(4-Butoxy-benzenesulfonylamino)-N-hydroxy-acetam...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human recombinant MMP2 using Mca-Lys-Pro- Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50429818(CHEMBL2337691)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human recombinant MMP2 using Mca-Lys-Pro- Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50175548(N-Hydroxy-2-(4-phenoxy-benzenesulfonylamino)-aceta...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain using Mca-Lys-Pro- Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human PDGFRbeta by kinase inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of recombinant human PDGFRbeta using Ulight-Poly GAT[EAY(1:1:1)]n as substrate measured after 30 mins by LANCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain using Mca-Lys-Pro- Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human CDK1 by kinase inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human recombinant MMP13 using Mca-Lys-Pro- Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50383010(CHEMBL2030706)
Affinity DataIC50: 5.34nMAssay Description:Antagonist activity at human A2B receptor expressed in CHO cells assessed as inhibition of NECA-mediated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50318272(1-(2-benzyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4...)
Affinity DataIC50: 5.70nMAssay Description:Antagonist activity human recombinant adenosine A3 receptor expressed in CHO cells assessed as blockade of NECA-mediated inhibition of forskolin-stim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50175535(2-(4-Butoxy-benzenesulfonylamino)-N-hydroxy-acetam...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant MMP13 using Mca-Lys-Pro- Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50318271(N-(2-benzyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4...)
Affinity DataIC50: 7.60nMAssay Description:Antagonist activity human recombinant adenosine A3 receptor expressed in CHO cells assessed as blockade of NECA-mediated inhibition of forskolin-stim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50318269(1-(2-benzyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4...)
Affinity DataIC50: 8.20nMAssay Description:Antagonist activity human recombinant adenosine A3 receptor expressed in CHO cells assessed as blockade of NECA-mediated inhibition of forskolin-stim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of recombinant human Src using Ulight-Poly GAT[EAY(1:1:1)]n as substrate measured after 10 mins by LANCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of human Src kinase by kinase inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50102286(10-benzyl-3-furan-2-yl-10H-benzo[4,5]imidazo[2,1-c...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human A2B receptor expressed in CHO cells assessed as inhibition of NECA-mediated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylc...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MMP2 using Mca-Lys-Pro- Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50429817(CHEMBL2337696)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MMP2 using Mca-Lys-Pro- Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human AurA kinase by kinase inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50224351(N-(8-chloro-1-oxo-2-p-tolyl-1H-3,3a,5,9b-tetraaza-...)
Affinity DataIC50: 11.6nMAssay Description:Antagonist activity at human adenosine A3 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50165335(2-(4-Chloro-phenyl)-5H-3,3a,5,9b-tetraaza-cyclopen...)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at human adenosine A3 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human Akt1 by kinase inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50102282(3,10-Diphenyl-10H-benzo[4,5]imidazo[2,1-c][1,2,4]t...)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human A2B receptor expressed in CHO cells assessed as inhibition of NECA-mediated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50383008(CHEMBL225154)
Affinity DataIC50: 15.3nMAssay Description:Antagonist activity at human A2B receptor expressed in CHO cells assessed as inhibition of NECA-mediated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
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