BindingDB PrimarySearch_ki

Found 1579 with Last Name = 'merk' and Initial = 'd'

Cysteinyl leukotriene receptor 1(GUINEA PIG)
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50009073(4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol...)

Ki: 0.300nMAssay Description:Displacement of [3H]LTD4 from cysteinyl leukotriene receptor 1 in Hartley guinea pig parenchymal membrane after 30 mins by liquid scintillation count...More data for this Ligand-Target Pair

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3D Structure (crystal)

Cysteinyl leukotriene receptor 1(GUINEA PIG)
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50227367(CHEMBL48435)

Ki: 0.800nMAssay Description:Displacement of [3H]LTD4 from cysteinyl leukotriene receptor 1 in Hartley guinea pig parenchymal membrane after 30 mins by liquid scintillation count...More data for this Ligand-Target Pair

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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL

PNG

BDBM50518072(CHEMBL4581645)

Ki: 1.20nMAssay Description:Displacement of [3H]-Way100635 from 5HT1A (unknown origin) expressed in CHO cell membranesMore data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL

PNG

BDBM50518072(CHEMBL4581645)

Ki: 3nMAssay Description:Displacement of [3H]-N-methylspiperone from dopamine D3 receptor (unknown origin) expressed in HEK293 cell membranesMore data for this Ligand-Target Pair

PDB Reactome pathway
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D(4) dopamine receptor(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL

PNG

BDBM50518072(CHEMBL4581645)

Ki: 6.5nMAssay Description:Displacement of [3H]-N-methylspiperone from dopamine D4 receptor (unknown origin) expressed in HEK293 cell membranesMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Cysteinyl leukotriene receptor 1(GUINEA PIG)
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50015529(4-(5-Cyclopentyloxycarbonylamino-1-methyl-1H-indol...)

Ki: 157nMAssay Description:Displacement of [3H]LTD4 from cysteinyl leukotriene receptor 1 in Hartley guinea pig parenchymal membrane after 30 mins by liquid scintillation count...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50530480(CHEMBL4445524)

Ki: 4.80E+3nMAssay Description:Competitive inhibition of full length human soluble epoxide hydrolase pre-incubated for 30 mins before DiFMUP substrate addition by fluorescence base...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50530480(CHEMBL4445524)

Ki: 4.80E+3nMAssay Description:Competitive inhibition of full length human soluble epoxide hydrolase pre-incubated for 30 mins before DiFMUP substrate addition by fluorescence base...More data for this Ligand-Target Pair

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Peptidylglycine alpha-amidating monooxygenase(Rattus norvegicus)
University of South Florida

Curated by ChEMBL

PNG

BDBM50273316(CHEMBL509495 | N-dansyl-Tyr-Val-D-Ala)

Ki: 4.70E+5nMAssay Description:Inhibition of rat recombinant peptidylglycine alpha-amidating monooxygenase assessed as inhibition of N-dansyl-Tyr-Val-Gly amidationMore data for this Ligand-Target Pair

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Peptidylglycine alpha-amidating monooxygenase(Rattus norvegicus)
University of South Florida

Curated by ChEMBL

PNG

BDBM50273962(CHEMBL445286 | Phenylthioacetylglycine)

Ki: 3.80E+6nMAssay Description:Inhibition of rat recombinant peptidylglycine alpha-amidating monooxygenase assessed as inhibition of N-dansyl-Tyr-Val-Gly amidationMore data for this Ligand-Target Pair

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Cysteinyl leukotriene receptor 1(GUINEA PIG)
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50023198(8-[4-(4-phenylbutyloxy)benzoyl]amino-2-(tetrazol-5...)

IC50: 0.0440nMAssay Description:Displacement of [3H]ICI from cysteinyl leukotriene receptor 1 in Hartley guinea pig lung membrane after 30 mins by liquid scintillation counting meth...More data for this Ligand-Target Pair

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3D Structure (crystal)

Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50241116(CHEMBL4066332)

IC50: 1nMAssay Description:Inhibition of sEH in human HepG2 cells using 14(15)-EET-d11 as substrate assessed as reduction in conversion of 14(15)-EET-d11 to 14(15)-DHET-d11 pre...More data for this Ligand-Target Pair

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Bile acid receptor(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50463011(CHEMBL4241985)

IC50: 1.30nMAssay Description:Antagonist activity at full length human FXR expressed in HeLa cells co-expressing BSEP-pGL3/pSG5-hRXR after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair

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Cysteinyl leukotriene receptor 1(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50009073(4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol...)

IC50: 1.80nMAssay Description:Inhibition of cysteinyl leukotriene receptor 1 (unknown origin) expressed in HEK293 cell membranes after 45 mins by scintillation spectrometryMore data for this Ligand-Target Pair

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3D Structure (crystal)

Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50586964(CHEMBL5074984)

IC50: 2nMAssay Description:Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50586969(CHEMBL5088299)

IC50: 2nMAssay Description:Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50581277(CHEMBL5089068)

IC50: 2nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by fl...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50586961(CHEMBL5078180)

IC50: 2nMAssay Description:Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50586956(CHEMBL5075652)

IC50: 2nMAssay Description:Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...More data for this Ligand-Target Pair

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Cysteinyl leukotriene receptor 1(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50239015(CHEBI:6993 | MK-476 | Montelukast Sodium | Singula...)

IC50: 2.30nMAssay Description:Inhibition of cysteinyl leukotriene receptor 1 (unknown origin) expressed in HEK293 cell membranes after 45 mins by scintillation spectrometryMore data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50586954(CHEMBL5079563)

IC50: 3nMAssay Description:Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50586962(CHEMBL5081457)

IC50: 3nMAssay Description:Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50586945(CHEMBL5084314)

IC50: 3nMAssay Description:Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50586963(CHEMBL5090087)

IC50: 3nMAssay Description:Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50586965(CHEMBL5074074)

IC50: 3nMAssay Description:Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50581272(CHEMBL5086882)

IC50: 4nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by fl...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50586955(CHEMBL5090873)

IC50: 4nMAssay Description:Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50241116(CHEMBL4066332)

IC50: 4.10nMAssay Description:Inhibition of recombinant v-Abl tyrosine kinase.More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50241116(CHEMBL4066332)

IC50: 4.10nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by fl...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50581267(CHEMBL5092609)

IC50: 4.30nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by fl...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Cysteinyl leukotriene receptor 1(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50023198(8-[4-(4-phenylbutyloxy)benzoyl]amino-2-(tetrazol-5...)

IC50: 4.40nMAssay Description:Inhibition of cysteinyl leukotriene receptor 1 (unknown origin) expressed in HEK293 cell membranes after 45 mins by scintillation spectrometryMore data for this Ligand-Target Pair

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3D Structure (crystal)

Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50586960(CHEMBL5081013)

IC50: 5nMAssay Description:Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50586966(CHEMBL5091134)

IC50: 5nMAssay Description:Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50586944(CHEMBL5090821)

IC50: 5nMAssay Description:Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50586947(CHEMBL5087833)

IC50: 5nMAssay Description:Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50586959(CHEMBL5092964)

IC50: 6nMAssay Description:Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50586952(CHEMBL5094953)

IC50: 6nMAssay Description:Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50586949(CHEMBL5080474)

IC50: 6nMAssay Description:Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50586948(CHEMBL5087046)

IC50: 6nMAssay Description:Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50581271(CHEMBL5092029)

IC50: 6.10nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by fl...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50586943(CHEMBL5087861)

IC50: 7nMAssay Description:Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50581268(CHEMBL5093975)

IC50: 7nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by fl...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50581278(CHEMBL5081303)

IC50: 7.80nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by fl...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50586946(CHEMBL5084336)

IC50: 8nMAssay Description:Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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3D Structure (crystal)

Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50241151(CHEMBL4087681)

IC50: 8.90nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition measured for 30 mins by fluoresc...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50581284(CHEMBL5094442)

IC50: 9nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by fl...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Bile acid receptor(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50463011(CHEMBL4241985)

IC50: 9.20nMAssay Description:Antagonist activity at full length human FXR expressed in HeLa cells co-expressing BSEP-pGL3/pSG5-hRXR assessed as inhibition of GW4064-induced recep...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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KEGG PC cid PC sid

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50581285(CHEMBL5083711)

IC50: 10nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by fl...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Bifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Goethe-University

Curated by ChEMBL

PNG

BDBM50586956(CHEMBL5075652)

IC50: 10nMAssay Description:Inhibition of N-terminal His-tagged mouse sEH (2 to 554 residues) expressed in Escherichia coli Rosetta2 (DE3) assessed as reduction in 6-methoxy-2-n...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50581266(CHEMBL5080537)

IC50: 11nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by fl...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Displayed 1 to 50 (of 1579 total ) | Next | Last >>

Filter my 1579 hits

Targets 30▿
- Bile acid receptor 277
- Peroxisome proliferator-activated receptor gamma 275
- Bifunctional epoxide hydrolase 2 223
- Retinoic acid receptor RXR-alpha 162
- Retinoic acid receptor RXR-beta 137
- Peroxisome proliferator-activated receptor alpha 118
- Retinoic acid receptor RXR-gamma 116
- Peroxisome proliferator-activated receptor delta 96
- Nuclear receptor subfamily 4 group A member 2 81
- Nuclear receptor subfamily 2 group E member 1 30
- Cysteinyl leukotriene receptor 1 9
- Thyroid hormone receptor alpha 6
- Oxysterols receptor LXR-beta 6
- Oxysterols receptor LXR-alpha 6
- Protein ENL 5
- Prostaglandin G/H synthase 2 4
- Prostaglandin G/H synthase 1 4
- Thyroid hormone receptor beta 4
- Prothrombin 3
- Peptidylglycine alpha-amidating monooxygenase 3
- Retinoic acid receptor alpha 2
- Nuclear receptor subfamily 1 group I member 3 2
- Retinoic acid receptor gamma 2
- Retinoic acid receptor beta 2
- Arachidonate 5-lipoxygenase-activating protein 1
- G-protein coupled bile acid receptor 1 1
- D(4) dopamine receptor 1
- D(3) dopamine receptor 1
- Nuclear receptor subfamily 1 group I member 2 1
- 5-hydroxytryptamine receptor 1A 1
- ...
Publications 35▿
- J Med Chem 62: 2112-2126 (2019) 256
- J Med Chem 64: 5123-5136 (2021) 123
- Bioorg Med Chem 23: 499-514 (2015) 107
- J Med Chem 64: 17259-17276 (2021) 105
- ACS Med Chem Lett 10: 203-208 (2019) 87
- J Med Chem 60: 7703-7724 (2017) 81
- J Med Chem 59: 61-81 (2016) 77
- J Med Chem 64: 10393-10402 (2021) 66
- J Med Chem 62: 8443-8460 (2019) 54
- J Med Chem 63: 4555-4561 (2020) 52
- J Med Chem 60: 7199-7205 (2017) 48
- J Med Chem 64: 9525-9536 (2021) 48
- ACS Med Chem Lett 10: 1346-1352 (2019) 46
- J Med Chem 57: 8035-55 (2014) 45
- J Med Chem 63: 8369-8379 (2020) 35
- J Med Chem 64: 15126-15140 (2021) 35
- J Med Chem 63: 6727-6740 (2020) 32
- J Med Chem 65: 9548-9563 (2022) 30
- J Med Chem 61: 5442-5447 (2018) 29
- Bioorg Med Chem 27: (2019) 28
- Bioorg Med Chem 26: 4240-4253 (2018) 26
- J Med Chem 61: 5758-5764 (2018) 21
- ACS Med Chem Lett 12: 267-274 (2021) 21
- J Med Chem 64: 8727-8738 (2021) 18
- J Med Chem 64: 2659-2668 (2021) 16
- J Med Chem 63: 10908-10920 (2020) 15
- J Med Chem 60: 5235-5266 (2017) 13
- Bioorg Med Chem 22: 2447-60 (2014) 13
- J Med Chem 65: 2288-2296 (2022) 12
- Bioorg Med Chem 23: 3490-8 (2015) 12
- J Med Chem 64: 2815-2828 (2021) 9
- Bioorg Med Chem Lett 27: 1193-1198 (2017) 8
- J Med Chem 61: 10929-10934 (2018) 5
- J Med Chem 62: 420-444 (2019) 3
- Bioorg Med Chem 16: 10061-74 (2008) 3
Institutions 8▿
- Goethe-University Frankfurt 934
- Goethe University Frankfurt 440
- Goethe-University 105
- Swiss Federal Institute of Technology (ETH) 29
- Fraunhofer Institute for Molecular Biology and Applied Ecology IME 28
- Goethe University 25
- New York University 15
- University of South Florida 3
Affinity: 0.044 to 3.8E+6 nM▿
- Ki 10
- IC50 339
- Kd 46
- EC50 1184
- Affinity ≤ nM
Xtal structures: 34
Docked structures: 4
Catalog Cmpds: 136