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TargetCollagenase 3(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM32416(furan-2-carboxamide deriv., 28)
Affinity DataIC50:  2nMpH: 7.5 T: 37°CAssay Description:MMP-13 was assessed by using the EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.). This kit uses a 5-FAM/QXL 520 fluorescence resonance 10 energy tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin G(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349174(CHEMBL1807526)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM32417(furan-2-carboxamide deriv., 29)
Affinity DataIC50:  4nMpH: 7.5 T: 37°CAssay Description:MMP-13 was assessed by using the EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.). This kit uses a 5-FAM/QXL 520 fluorescence resonance 10 energy tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin G(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349176(CHEMBL1807531)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM32412(furan-2-carboxamide deriv., 24)
Affinity DataIC50:  6nMpH: 7.5 T: 37°CAssay Description:MMP-13 was assessed by using the EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.). This kit uses a 5-FAM/QXL 520 fluorescence resonance 10 energy tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM32414(furan-2-carboxamide deriv., 26)
Affinity DataIC50:  6nMpH: 7.5 T: 37°CAssay Description:MMP-13 was assessed by using the EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.). This kit uses a 5-FAM/QXL 520 fluorescence resonance 10 energy tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin G(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349173(CHEMBL1807638)
Affinity DataIC50:  7nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin G(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349183(CHEMBL1807538)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin G(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349178(CHEMBL1807535)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin G(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349190(CHEMBL1807641)
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin G(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349177(CHEMBL1807639)
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin G(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349175(CHEMBL1807637)
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin G(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349186(CHEMBL1807539)
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin G(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349184(CHEMBL1807527)
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin G(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349187(CHEMBL1807528)
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin G(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349185(CHEMBL1807529)
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin G(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349180(CHEMBL1807530)
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin G(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349188(CHEMBL1807532)
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin G(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349189(CHEMBL1807533)
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin G(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349182(CHEMBL1807534)
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin G(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349179(CHEMBL1807537)
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin G(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349181(CHEMBL1807536)
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM32402(furan-2-carboxamide deriv., 10)
Affinity DataIC50:  17nMpH: 7.5 T: 37°CAssay Description:MMP-13 was assessed by using the EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.). This kit uses a 5-FAM/QXL 520 fluorescence resonance 10 energy tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetChymase(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349191(CHEMBL1807642)
Affinity DataIC50:  22nMAssay Description:Inhibition of human chymase after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCathepsin G(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349172(CHEMBL1807640)
Affinity DataIC50:  22nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM32415(furan-2-carboxamide deriv., 27)
Affinity DataIC50:  25nMpH: 7.5 T: 37°CAssay Description:MMP-13 was assessed by using the EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.). This kit uses a 5-FAM/QXL 520 fluorescence resonance 10 energy tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetChymase(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349172(CHEMBL1807640)
Affinity DataIC50:  25nMAssay Description:Inhibition of human chymase after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM32399(furan-2-carboxamide deriv., 7)
Affinity DataIC50:  31nMpH: 7.5 T: 37°CAssay Description:MMP-13 was assessed by using the EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.). This kit uses a 5-FAM/QXL 520 fluorescence resonance 10 energy tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM32411(furan-2-carboxamide deriv., 20)
Affinity DataIC50:  32nMpH: 7.5 T: 37°CAssay Description:MMP-13 was assessed by using the EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.). This kit uses a 5-FAM/QXL 520 fluorescence resonance 10 energy tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM32413(furan-2-carboxamide deriv., 25)
Affinity DataIC50:  40nMpH: 7.5 T: 37°CAssay Description:MMP-13 was assessed by using the EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.). This kit uses a 5-FAM/QXL 520 fluorescence resonance 10 energy tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM32398(furan-2-carboxamide deriv., 6)
Affinity DataIC50:  57nMpH: 7.5 T: 37°CAssay Description:MMP-13 was assessed by using the EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.). This kit uses a 5-FAM/QXL 520 fluorescence resonance 10 energy tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM32397(furan-2-carboxamide deriv., 5)
Affinity DataIC50:  63nMpH: 7.5 T: 37°CAssay Description:MMP-13 was assessed by using the EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.). This kit uses a 5-FAM/QXL 520 fluorescence resonance 10 energy tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetChymase(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349173(CHEMBL1807638)
Affinity DataIC50:  65nMAssay Description:Inhibition of human chymase after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetChymase(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349174(CHEMBL1807526)
Affinity DataIC50:  70nMAssay Description:Inhibition of human chymase after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM32401(furan-2-carboxamide deriv., 9)
Affinity DataIC50:  88nMpH: 7.5 T: 37°CAssay Description:MMP-13 was assessed by using the EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.). This kit uses a 5-FAM/QXL 520 fluorescence resonance 10 energy tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetChymase(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349175(CHEMBL1807637)
Affinity DataIC50:  140nMAssay Description:Inhibition of human chymase after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetChymase(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349176(CHEMBL1807531)
Affinity DataIC50:  170nMAssay Description:Inhibition of human chymase after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM32400(furan-2-carboxamide deriv., 8)
Affinity DataIC50:  180nMpH: 7.5 T: 37°CAssay Description:MMP-13 was assessed by using the EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.). This kit uses a 5-FAM/QXL 520 fluorescence resonance 10 energy tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetChymase(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349192(CHEMBL1807643)
Affinity DataIC50:  180nMAssay Description:Inhibition of human chymase after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCollagenase 3(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM32410(furan-2-carboxamide deriv., 19)
Affinity DataIC50:  220nMpH: 7.5 T: 37°CAssay Description:MMP-13 was assessed by using the EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.). This kit uses a 5-FAM/QXL 520 fluorescence resonance 10 energy tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetChymase(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349177(CHEMBL1807639)
Affinity DataIC50:  220nMAssay Description:Inhibition of human chymase after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM32403(furan-2-carboxamide deriv., 12)
Affinity DataIC50:  245nMpH: 7.5 T: 37°CAssay Description:MMP-13 was assessed by using the EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.). This kit uses a 5-FAM/QXL 520 fluorescence resonance 10 energy tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetChymase(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349178(CHEMBL1807535)
Affinity DataIC50:  280nMAssay Description:Inhibition of human chymase after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM32408(furan-2-carboxamide deriv., 17)
Affinity DataIC50:  290nMpH: 7.5 T: 37°CAssay Description:MMP-13 was assessed by using the EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.). This kit uses a 5-FAM/QXL 520 fluorescence resonance 10 energy tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM32395(furan-2-carboxamide deriv., 1)
Affinity DataIC50:  430nMpH: 7.5 T: 37°CAssay Description:MMP-13 was assessed by using the EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.). This kit uses a 5-FAM/QXL 520 fluorescence resonance 10 energy tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetCollagenase 3(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM32406(furan-2-carboxamide deriv., 15)
Affinity DataIC50:  460nMpH: 7.5 T: 37°CAssay Description:MMP-13 was assessed by using the EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.). This kit uses a 5-FAM/QXL 520 fluorescence resonance 10 energy tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM32407(furan-2-carboxamide deriv., 16)
Affinity DataIC50:  480nMpH: 7.5 T: 37°CAssay Description:MMP-13 was assessed by using the EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.). This kit uses a 5-FAM/QXL 520 fluorescence resonance 10 energy tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetChymase(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349179(CHEMBL1807537)
Affinity DataIC50:  570nMAssay Description:Inhibition of human chymase after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetChymase(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349180(CHEMBL1807530)
Affinity DataIC50:  600nMAssay Description:Inhibition of human chymase after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM32396(furan-2-carboxamide deriv., 2)
Affinity DataIC50:  620nMpH: 7.5 T: 37°CAssay Description:MMP-13 was assessed by using the EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.). This kit uses a 5-FAM/QXL 520 fluorescence resonance 10 energy tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

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