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TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566781(CHEMBL4867273)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNicotinamide N-methyltransferase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566781(CHEMBL4867273)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of human recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50593249(CHEMBL5199870)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of HIV-1 protease using EDANS-RESGIFLETSKR-DABCYL as substrate preincubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50593251(CHEMBL5199920)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of HIV-1 protease using EDANS-RESGIFLETSKR-DABCYL as substrate preincubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50593248(CHEMBL5208859)
Affinity DataIC50:  0.290nMAssay Description:Inhibition of HIV-1 protease using EDANS-RESGIFLETSKR-DABCYL as substrate preincubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50593250(CHEMBL5180391)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of HIV-1 protease using EDANS-RESGIFLETSKR-DABCYL as substrate preincubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNicotinamide N-methyltransferase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566783(CHEMBL4859806)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50593258(CHEMBL5175402)
Affinity DataIC50:  0.440nMAssay Description:Inhibition of HIV-1 protease using EDANS-RESGIFLETSKR-DABCYL as substrate preincubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50593247(CHEMBL5194642)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of HIV-1 protease using EDANS-RESGIFLETSKR-DABCYL as substrate preincubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNicotinamide N-methyltransferase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566776(CHEMBL4847740)
Affinity DataIC50:  0.470nMAssay Description:Inhibition of human recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50593255(CHEMBL5201455)
Affinity DataIC50:  0.620nMAssay Description:Inhibition of HIV-1 protease using EDANS-RESGIFLETSKR-DABCYL as substrate preincubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566783(CHEMBL4859806)
Affinity DataIC50:  0.620nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50593245(CHEMBL5195759)
Affinity DataIC50:  0.680nMAssay Description:Inhibition of HIV-1 protease using EDANS-RESGIFLETSKR-DABCYL as substrate preincubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50593246(CHEMBL5183416)
Affinity DataIC50:  0.780nMAssay Description:Inhibition of HIV-1 protease using EDANS-RESGIFLETSKR-DABCYL as substrate preincubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNicotinamide N-methyltransferase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566782(CHEMBL4857394)
Affinity DataIC50:  0.930nMAssay Description:Inhibition of human recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566782(CHEMBL4857394)
Affinity DataIC50:  0.950nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50593257(CHEMBL5203523)
Affinity DataIC50:  0.990nMAssay Description:Inhibition of HIV-1 protease using EDANS-RESGIFLETSKR-DABCYL as substrate preincubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNicotinamide N-methyltransferase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566772(CHEMBL4878738)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566776(CHEMBL4847740)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566772(CHEMBL4878738)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNicotinamide N-methyltransferase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566784(CHEMBL4872872)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNicotinamide N-methyltransferase(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566784(CHEMBL4872872)
Affinity DataIC50:  2nMAssay Description:Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50593252(CHEMBL5205912)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of HIV-1 protease using EDANS-RESGIFLETSKR-DABCYL as substrate preincubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50593253(CHEMBL5189547)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of HIV-1 protease using EDANS-RESGIFLETSKR-DABCYL as substrate preincubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

LigandPNGBDBM346986(US10202379, Reference Example 730)
Affinity DataIC50:  2.52nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM346979(US10202379, Reference Example 719)
Affinity DataIC50:  2.60nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM346964(US10202379, Reference Example 666)
Affinity DataIC50:  3.36nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50593256(CHEMBL5186053)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of HIV-1 protease using EDANS-RESGIFLETSKR-DABCYL as substrate preincubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM346968(US10202379, Reference Example 691)
Affinity DataIC50:  3.67nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM346984(US10202379, Reference Example 726)
Affinity DataIC50:  3.74nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM346923(US10202379, Reference Example 602)
Affinity DataIC50:  5nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM346931(US10202379, Reference Example 619)
Affinity DataIC50:  5nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM346983(US10202379, Reference Example 724)
Affinity DataIC50:  5.07nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM346995(US10202379, Reference Example 772)
Affinity DataIC50:  5.22nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM346978(US10202379, Reference Example 716)
Affinity DataIC50:  5.54nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM346976(US10202379, Reference Example 711)
Affinity DataIC50:  5.57nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM346987(US10202379, Reference Example 731)
Affinity DataIC50:  5.76nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetNicotinamide N-methyltransferase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566775(CHEMBL4856854)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of human recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

LigandPNGBDBM346994(US10202379, Reference Example 771)
Affinity DataIC50:  5.89nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM346932(US10202379, Reference Example 621)
Affinity DataIC50:  6nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM346980(US10202379, Reference Example 720 | US10202379, Re...)
Affinity DataIC50:  6.96nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM346821(US10202379, Reference Example 446)
Affinity DataIC50:  7nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50593244(CHEMBL5201205)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of HIV-1 protease using EDANS-RESGIFLETSKR-DABCYL as substrate preincubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

LigandPNGBDBM346956(US10202379, Reference Example 654)
Affinity DataIC50:  8nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM346840(US10202379, Reference Example 470)
Affinity DataIC50:  8nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50593243(CHEMBL5204991)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of HIV-1 protease using EDANS-RESGIFLETSKR-DABCYL as substrate preincubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

LigandPNGBDBM346917(US10202379, Reference Example 594)
Affinity DataIC50:  11nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM346970(US10202379, Reference Example 704)
Affinity DataIC50:  11.1nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetNicotinamide N-methyltransferase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50566786(CHEMBL4866114)
Affinity DataIC50:  12nMAssay Description:Inhibition of human recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

LigandPNGBDBM346837(US10202379, Reference Example 463)
Affinity DataIC50:  12nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


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