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TargetMuscarinic acetylcholine receptor M4(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50015720((hyoscine)3-Hydroxy-2-phenyl-propionic acid 9-meth...)
Affinity DataKi:  0.140nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202918((S)-N-(2-fluoro-3-(trifluoromethyl)benzyl)-5-(4-cy...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor(Pig)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50015720((hyoscine)3-Hydroxy-2-phenyl-propionic acid 9-meth...)
Affinity DataKi:  0.210nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202900((S)-N-(3-(trifluoromethyl)benzyl)-5-(4-cyclohexylp...)
Affinity DataKi:  0.270nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202920(2(R)-[[4-(piperidin-1-yl)piperidin-1-yl]carbonylme...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Bovine)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50015720((hyoscine)3-Hydroxy-2-phenyl-propionic acid 9-meth...)
Affinity DataKi:  0.380nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202882((S)-N-(2,3-dichlorobenzyl)-5-(4-cyclohexylpiperazi...)
Affinity DataKi:  0.380nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM82423(CAS_132947 | NSC_132947 | TRIPITRAMINE)
Affinity DataKi:  0.400nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202902((S)-N-(2-fluoro-5-(trifluoromethyl)benzyl)-5-(4-cy...)
Affinity DataKi:  0.410nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202873((S)-N-(3-(trifluoromethyl)benzyl)-5-(4-(cyclohexyl...)
Affinity DataKi:  0.460nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202916((S)-N-(3-fluoro-5-(trifluoromethyl)benzyl)-5-(4-cy...)
Affinity DataKi:  0.510nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50176065(4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...)
Affinity DataKi:  0.580nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202860(2(R)-[[4-(piperidin-1-yl)piperidin-1-yl]carbonylme...)
Affinity DataKi:  0.660nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202871((S)-N-(3-chlorobenzyl)-5-(4-cyclohexylpiperazin-1-...)
Affinity DataKi:  0.660nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202877((S)-N-(3,5-difluorobenzyl)-5-(4-cyclohexylpiperazi...)
Affinity DataKi:  0.820nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202869((S)-N-(2-(trifluoromethyl)benzyl)-5-(4-cyclohexylp...)
Affinity DataKi:  0.930nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor(Pig)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM82423(CAS_132947 | NSC_132947 | TRIPITRAMINE)
Affinity DataKi:  0.970nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50064176(CHEMBL27673 | CHEMBL500996 | METHOCTRAMINE | N,N''...)
Affinity DataKi:  1.02nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202864(4-amino-1-benzyl-1-[(3S)-3-[(3S,4R)-2-oxo-3-[(4S)-...)
Affinity DataKi:  1.13nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202858(2(R)-[[4-(piperidin-1-yl)piperidin-1-yl]carbonylme...)
Affinity DataKi:  1.13nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202892((S)-N-(3-(trifluoromethyl)benzyl)-5-oxo-2-((3S,4R)...)
Affinity DataKi:  1.17nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202899(CHEMBL241826 | N-(3-(trifluoromethyl)benzyl)-3-oxo...)
Affinity DataKi:  1.17nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202851((S)-N-(3-(trifluoromethyl)benzyl)-5-oxo-2-((3S,4R)...)
Affinity DataKi:  1.19nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202910(2(R)-[[4-(piperidin-1-yl)piperidin-1-yl]carbonylme...)
Affinity DataKi:  1.27nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Bovine)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50176065(4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...)
Affinity DataKi:  1.31nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202852((S)-N-(3-(trifluoromethyl)benzyl)-5-oxo-2-((3S,4R)...)
Affinity DataKi:  1.45nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202905(2(R)-[[4-(piperidin-1-yl)piperidin-1-yl]carbonylme...)
Affinity DataKi:  1.49nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50176065(4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...)
Affinity DataKi:  1.69nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202922((S)-N-(3-(trifluoromethyl)benzyl)-4-oxo-2-((3S,4R)...)
Affinity DataKi:  1.89nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202915((S)-N-(3-(trifluoromethyl)benzyl)-5-oxo-2-((3S,4R)...)
Affinity DataKi:  1.95nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor(Pig)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50176065(4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...)
Affinity DataKi:  2.04nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Bovine)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM82423(CAS_132947 | NSC_132947 | TRIPITRAMINE)
Affinity DataKi:  2.39nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202849(CHEMBL439398 | N-(3-(trifluoromethyl)benzyl)-3-oxo...)
Affinity DataKi:  3.39nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202844((3S)-3-amino-1-benzyl-1-[(3S)-3-[(3S,4R)-2-oxo-3-[...)
Affinity DataKi:  3.60nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202842((R)-N-(3-(trifluoromethyl)benzyl)-4-oxo-2-((3S,4R)...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM81799(CAS_98299-40-2 | HHSiD | NSC_3602 | hexahydrosilad...)
Affinity DataKi:  4.16nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202909((S)-N-(3,5-bis(trifluoromethyl)benzyl)-5-(4-cycloh...)
Affinity DataKi:  4.45nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202906((S)-N-(3-(trifluoromethyl)benzyl)-4-(4-benzyl-1,4-...)
Affinity DataKi:  5.12nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202903(4-amino-1-benzyl-1-[(3R)-3-[(3S,4R)-2-oxo-3-[(4S)-...)
Affinity DataKi:  5.58nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202881((R)-N-(3-(trifluoromethyl)benzyl)-5-(4-cyclohexylp...)
Affinity DataKi:  5.84nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Bovine)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM82376(CAS_80880-90-6 | NSC_5387 | TELENZEPINE)
Affinity DataKi:  5.88nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202862(2(R)-[[4-(piperidin-1-yl)piperidin-1-yl]carbonylme...)
Affinity DataKi: >6nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50071173((3R,4R,4aS,8aR)-4-[(E)-2-((2S,6S)-1,6-Dimethyl-pip...)
Affinity DataKi:  6.02nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202914(CHEMBL395778 | N-(3-(trifluoromethyl)benzyl)-3-(4-...)
Affinity DataKi:  6.5nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202879((R)-N-(3-(trifluoromethyl)benzyl)-4-oxo-2-((3S,4R)...)
Affinity DataKi:  7.90nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202866(2(R)-[[ 4-[2-(1-piperidinyl)ethyl]piperidin-1-yl]c...)
Affinity DataKi:  8.70nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202872((S)-N1-(3-(trifluoromethyl)benzyl)-2-((3S,4R)-2-ox...)
Affinity DataKi:  9nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202843((S)-N-(3-(trifluoromethyl)benzyl)-5-oxo-2-((3S,4R)...)
Affinity DataKi:  9.90nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
Lehigh University

Curated by ChEMBL
LigandPNGBDBM50202891((R)-N-(3-(trifluoromethyl)benzyl)-5-(4-butylpipera...)
Affinity DataKi:  10.5nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor(Pig)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50071173((3R,4R,4aS,8aR)-4-[(E)-2-((2S,6S)-1,6-Dimethyl-pip...)
Affinity DataKi:  10.7nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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